Curcumin-loaded albumin nanoparticles synthesis, characterization and in-vitro evaluation of cytotoxic effects against U-87 MG cells

Masoumeh Keshavarz; Navid Ahmadi Nasab; Maryam Saeidifar; Sara Nikoofal; Omid Safa

Volume 7, Issue 3 , July 2022, , Pages 245-253

https://doi.org/10.22034/nmrj.2022.03.004

Abstract
  Objective(s): Curcumin (Cur) as a natural bioactive compound has shown potential capability to fight a variety of malignancies. In this study, bovine serum albumin nanoparticles (BSA NPs) were applied to improve bioavailability and increase the effectiveness of the hydrophobic curcumin against human ...  Read More

Preparation and characterization of bovine serum albumin nanocarrier conjugated to exosome to sustained release of 5-flurouracil: Release and antitumoral evaluation

Ghazaleh Rahimi; Maryam Saeidifar; Monireh Ganjali; Esmaeil Salahi

Volume 7, Issue 1 , January 2022, , Pages 73-82

https://doi.org/10.22034/nmrj.2022.01.007

Abstract
  One of the new strategies for improving of chemotherapy in cancer treatment is the use of nanocarriers for sustained release of anticancer drugs. The present study aims to investigate the bovine serum albumin nanoparticles (BSANP) with exosomes (Exo) for prolonged release of 5-Flurouracil (5FU) as an ...  Read More