Chitosan/PVA nanofibers for implantable drug delivery systems

Fatemeh Madani; Basil Mujokoro; Shima Mohammadi; Masood Khosravani; Mahdi Adabi

Volume 7, Issue 2 , April 2022, , Pages 150-155

  In this study, we prepared methotrexate (MTX) loaded chitosan/polyvinyl alcohol (PVA) nanofibers using electrospinning method. The prepared nanofiber mats were soaked into the glutaraldehyde solution for crosslinking. The ratio of chitosan/PVA was 1:9 and 1:7, and the crosslinking time was 24 hrs and ...  Read More

Preparation of Methotrexate loaded PLGA nanoparticles coated with PVA and Poloxamer188

Fatemeh Madani; Arash Goodarzi; Mansoureh Hashemi; Basil Mujokoro; Masood Khosravani; Mahdi Adabi

Volume 3, Issue 1 , January 2018, , Pages 19-24

  Objective(s): Nanoparticles offer an attractive platform for drug delivery through a wide variety of the body's physiological barriers. Furthermore, modification of nanoparticle surface with moeites such as Poloxamer188 can enhance their accumulation and localization at disease site. In this work, ...  Read More