drug delivery
Design and evaluation of sesamol loaded hyaluronic acid functionalized phospholipid nanovesicles: DPPH radical scavenging potential assay

Manish Kumar Gupta; Vipul A Sansare; Birendra Shrivastava; Santosh Jadhav; Prashant Gurav

Volume 6, Issue 4 , November 2021, , Pages 347-351


  Objective(s): The unfavorable physicochemical properties of well recognized antioxidant phytoactive sesamol limits its oral bioavailability as well as use as an effective therapeutic agent. Thus present study was started with aim to fabricate sesamol loaded hyaluronic acid anchored phospholipid nanovesicles ...  Read More

Design, fabrication, and characterization of sesamol loaded polymeric nanoparticles: In vivo hepatoprotective potential in Wistar rats

Vipul A Sansare; Manish Kumar Gupta; Birendra Shrivastava; Santosh Jadhav

Volume 6, Issue 3 , September 2021, , Pages 296-303


  Objective(s): Liver diseases affect millions of people worldwide, which are difficult to treat with conventional drug delivery. Numerous drugs have been investigated for treatment of diseases associated with liver however correct drug delivery system need to be find for delivery of drugs. Sesamol is ...  Read More

Chemometric approach for developing nanostructured self-emulsifying drug delivery systems of rosuvastatin calcium containing a dietary lipid with improved biopharmaceutical performance

Jagdish Kumar Arun; Rajeshwar Vodeti; Birendra Shrivastava; Vasudha Bakshi

Volume 5, Issue 3 , September 2020, , Pages 245-255


  Objective(s): The present work deals with the development of nanostructured self-emulsifying delivery system of rosuvastatin calcium containing a dietary lipid by chemometry principles for improving the biopharmaceutical performance of the drug. Excipient screening was performed on the basis of solubility ...  Read More