Curcumin-loaded albumin nanoparticles synthesis, characterization and in-vitro evaluation of cytotoxic effects against U-87 MG cells

Masoumeh Keshavarz; Navid Ahmadi Nasab; Maryam Saeidifar; Sara Nikoofal; Omid Safa

Volume 7, Issue 3 , July 2022, , Pages 245-253

  Objective(s): Curcumin (Cur) as a natural bioactive compound has shown potential capability to fight a variety of malignancies. In this study, bovine serum albumin nanoparticles (BSA NPs) were applied to improve bioavailability and increase the effectiveness of the hydrophobic curcumin against human ...  Read More

Exosome-loaded Paclitaxel: Preparation and toxicity evaluation on two glioblastoma cell lines

Soodeh Salarpour; Abbas Pardakhty; Meysam Ahmadi-Zeidabadi; Mostafa Pournamdari; Hamid Forootanfar; Marzie Esmaeeli; Sepehr Afsharipour

Volume 4, Issue 4 , December 2019, , Pages 239-246

  Objective(s): Exosomes are endogenous nanovesicles act as intercellular communication tools which have been considered to utilize as drug delivery systems. As transporting therapeutic molecules into brain has obstacles, preparing exosomes which have the potential to pass through its barriers is great ...  Read More