drug delivery
Structural and morphological investigation of polycaprolactone multi-component scaffold containing collagen microsphere/bioglass nanoparticles

Hamed Sahrapeyma; Azadeh Asefnejad; Mahmoud Azami; Esmaeil Sadroddiny

Volume 7, Issue 4 , October 2022, , Pages 338-349


  Bioglass nano-ceramic containing cerium (Ce) with various amounts of Ce were synthesized by sol-gel method for enhanacement polycaprolactone (PCL) fiber scaffolds for tissue engineering approaches. The prepared scaffold was analysize using scanning electron microscopy (SEM) and X-ray diffraction (XRD) ...  Read More

drug delivery
Cancer stem cells (CSCs): the blockage of metastatic and stemness properties by metal nanoparticles

Samin Shokravi; Farnoosh Ebrahimzadeh; Farnoosh Farahbod; Aref Nooraei

Volume 6, Issue 4 , November 2021, , Pages 304-326


  Cancer stem cells (CSCs) are comprised of hierarchically-organized subpopulations of cells with  distinguished phenotypes and tumorigenic capabilities that concrete to metastasis and cancer recurrence. According to related studies, their presence stands as the main reason of cancer associated fatalities. ...  Read More

drug delivery
Preparation and Characterization of PLGA Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle Via Oil in Water Emulsion Evaporation Technique

Emmellie Laura Albert; Che Azurahanim Che Abdullah; Ghazaleh Bahmanrokh; Yuki Shirosaki; Toshiki Miyazaki; Siti Norzulfikaini Yaacob

Volume 6, Issue 4 , November 2021, , Pages 337-346


  Current research had successfully encapsulated magnetic nanoparticles (MNP) with selective estrogen receptor drug tamoxifen citrate (TAM) using Poly (d,l-lactice-co-glycolide acid) (PLGA 75:25) via oil in water emulsion technique. TAM is a good example of a drug that is difficult to dissolve. TAM is ...  Read More

drug delivery
Design and evaluation of sesamol loaded hyaluronic acid functionalized phospholipid nanovesicles: DPPH radical scavenging potential assay

Manish Kumar Gupta; Vipul A Sansare; Birendra Shrivastava; Santosh Jadhav; Prashant Gurav

Volume 6, Issue 4 , November 2021, , Pages 347-351


  Objective(s): The unfavorable physicochemical properties of well recognized antioxidant phytoactive sesamol limits its oral bioavailability as well as use as an effective therapeutic agent. Thus present study was started with aim to fabricate sesamol loaded hyaluronic acid anchored phospholipid nanovesicles ...  Read More

drug delivery
In vitro release kinetics study of Diallyl Disulphide entrapped into mesoporous silica matrix & evaluation of its antimicrobial activity

Pritha Pal; Rajib Dey; Satadal Das; Mahua Ghosh Chaudhuri

Volume 6, Issue 2 , April 2021, , Pages 148-157


  Diallyl disulphide (DADS) is one of the major constituents of garlic which has antimicrobial activity as well as many other advantages for human health. Sulphur present in DADS is main the reactive one to deal with the microbes. Mesoporous silica nanomaterial (MSNs) is evaluated as a potential drug carrier ...  Read More

drug delivery
Overcoming the antibiotic resistance of Acinetobacter baumannii by using nanofluid containing functionalized carbon nanotubes

Mohammad Reza Yazdani; Mojgan Sheikhpour; Seyed Davar Siadat; Parvaneh Safarian

Volume 6, Issue 2 , April 2021, , Pages 179-187


  Objective: Acinetobacter baumannii is critical for healthcare-associated infections with significant regional differences in the resistance rate, but its risk factors and infection trends have not been well studied. Carbon nanotubes are substantially cylindrical molecules made entirely of carbon atoms ...  Read More