ORIGINAL_ARTICLE
Synthesis and Charactrization of Au Nanocomposits by Green Capping Agent: Pomegranate juice For Antibacterial Activity
Objective(s): In this work, pomegranate juice was used as a capping agent for self- assembly to form particles-like Au nanostructures in the presence of AuHCl4.3H2O as aurate source. Besides, to investigate the concentration effect of pomegranate juice as the green capping agent on the morphology and particle size of final products several experiments were performed. Methods: The as-synthesized products were characterized by X-ray diffraction (XRD), scanning electron microscope (SEM), transmission electron microscope (TEM), Fourier transformation infrared (FT-IR). Au nanostructures exhibited stronger antibacterial properties against Gram-negative bacteria (Salmonella typhi and Escherichia coli) than against Gram-positive bacteria (Staphyloccocus aureus and Staphyloccocus epidermidis). Results: Microwave irradiation provides a rapid and green method for the synthesis of AuNP. It favors the formation of small and uniform nanoparticles through a fast and homogeneous nucleation and crystallization. Both AuNPs nanocomposites showed antibacterial activity that is stronger against Gram-negative bacteria (E. coli and S. typhi) than against Gram-positive bacteria, (S. aureus and S. epidermidis) Conclusions: This rapid method of microwave radiation as compared to the classical synthesis, showed promising results in terms of size distribution, surface area, pore diameter and pore volume.
https://www.nanomedicine-rj.com/article_24908_d1fc9f887f6a3bfb3b11f3c264f57465.pdf
2017-04-01
73
77
10.22034/nmrj.2017.53588.1049
Nanostructure, Green Synthesis
Antibacterial properties
Au Nanoporous
Peyman
Rajaei
rajaei.iauk@gmail.com
1
Department of Biology, Kerman Branch, Islamic Azad University Kerman, Iran
LEAD_AUTHOR
Mehdi
Ranjbar
mehdi.ranjbar@outlook.com
2
Young Researchers and Elite Club, Kerman Branch, Islamic Azad University, Kerman, Iran
LEAD_AUTHOR
1.Ng EYK, Chua LT. Mesh-independent prediction of skin burns injury. J Med Eng Technol. 2000;24(6): 255-61.
1
2.Gidding CEM, Kellie SJ, Kamps WA, de Graaf SSN. Vincristine revisited. Crit Rev Oncol Hematol. 1999;29(3):267-87.
2
3.Coimbra P, Alves P, Valente TAM, Santos R, Correia IJ, Ferreira P. Sodium hyaluronate/chitosan polyelectrolyte complex scaffolds for dental pulp regeneration: Synthesis and characterization. Int J Biol Macromol. 2011;49(4):573-9.
3
4. Yu L, Lu Y, Man N, Yu SH, Wen P. Rare earth oxide nanocrystals induce autophagy in HeLa cells. Small. 2009; 5(24): 2784- 2787.
4
5.Yu W, France DM, Routbort JL, Choi SUS. Review and comparison of nanofluid thermal conductivity and heat transfer enhancements. Heat Transfer Eng. 2008;29(5):432- 60.
5
6.Chon CH, Kihm KD, Lee SP, Choi SUS. Empirical correlation finding the role of temperature and particle size for nanofluid (Al2O3) thermal conductivity enhancement. Appl Phys Lett. 2005;87(15):3107.
6
7.Das SK, Putra N, Thiesen P, Roetzel W. Temperature dependence of thermal conductivity enhancement for nanofluids. J Heat Transfer. 2003;125(4):567-74.
7
8.Li CH, Peterson G. Experimental investigation of temperature and volume fraction variations on the effective thermal conductivity of nanoparticle suspensions (nanofluids). J Appl Phys. 2006;99(8):84-94.
8
9.Wu C, Chang J, Wang J, Ni S, Zhai W. Preparation and characteristics of a calcium magnesium silicate (bredigite) bioactive ceramic. Biomaterials. 2005;26(2):2925–2931
9
10.Patlolla A, McGinnis B, Tchounwou P. Biochemical and histopathological evaluation of functionalized single‐walled carbon nanotubes in Swiss–Webster mice. J Appl Toxicol. 2011;31(1):75-83.
10
11.Chen R, Zhang L, Ge C, Tseng MT, Bai R, Qu Y, Subchronic toxicity and cardiovascular responses in spontaneously hypertensive rats after exposure to multiwalled carbon nanotubes by intratracheal instillation. Chem Res Toxicol. 2015;28(3):440-50.
11
12.Warheit DB, Laurence BR, Reed KL, Roach DH, Reynolds GAM, Webb TR. Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol Sci. 2004;77(1):117-25.
12
13.Yang S-T, Wang X, Jia G, Gu Y, Wang T, Nie H, Longterm accumulation and low toxicity of single-walled carbon nanotubes in intravenously exposed mice. Toxicol Lett. 2008;181(3):182-9.
13
14.Walker VG, Li Z, Hulderman T, Schwegler-Berry D, Kashon ML, Simeonova PP. Potential in vitro effects of carbon nanotubes on human aortic endothelial cells. Toxicol Appl Pharmacol. 2009;236(3):319-28.
14
15.Jin H-J, Fridrikh SV, Rutledge GC, Kaplan DL. Electrospinning Bombyx mori Silk with Poly(ethylene oxide). Biomacromolecules. 2002;3(6):1233-9
15
16.Rossoni G, Manfredi B, Civelli M, Berti F, Razzetti R. Combined simvastatin–manidipine protect against ischemia–reperfusion injury in isolated hearts from normocholesterolemic rats. Eur J Pharmacol. 2008;587(1):224-30.
16
17.Brown EE, Laborie M-PG. Bioengineering Bacterial Cellulose/Poly(ethylene oxide) Nanocomposites. Biomacromolecules. 2007;8(10):3074-81.
17
18. Daghrir R, Drogui P. Tetracycline antibiotics in the environment: a review. Environ chem lett. 2013;11(3):209- 27.
18
19.Teo WE, Ramakrishna S. A review on electrospinning design and nanofibre assemblies. Nanotechnology. 2006;17(14):89-106.
19
20.Borase HP, Salunke BK, Salunkhe RB, Patil CD, Hallsworth JE, Kim BS, Plant extract: a promising biomatrix for ecofriendly, controlled synthesis of silver nanoparticles. Appl Biochem Biotechnol. 2014;173(1):1-29
20
21.Mukherjee P, Ahmad A, Mandal D, senapati S, Sainkar S, Khan M, Fungus-mediated synthesis of silver nanoparticles and their immobilization in the mycelial matrix: a novel biological approach to nanoparticle synthesis. Nano Lett. 2001;1(10):5-9
21
22.Sharma NC, Sahi SV, Nath S, Parsons JG, Gardea-Torresde JL, Pal T. Synthesis of plant-mediated gold nanoparticles and catalytic role of biomatrix-embedded nanomaterials. Environ Sci Technol. 2007;41(14):37-42.
22
23.Korbekandi H, Iravani S, Abbasi S. Production of nanoparticles using organisms production of nanoparticles using organisms. Crit Rev Biotechnol. 2009;29(4):279-306.
23
24.Kotthaus S, Gunther B, Haug R, Schafer H. Study of isotropically conductive bondings filled with aggregates of nano-sized Ag-particles. IEEE Trans Compon Packag Manuf Technol A. 1997;20(1):15-20.
24
25.Singh D, Jain D, Upadhyay MK, Khandelwal N, Verma HN. Green synthesis of silver nanoparticles using Argemone mexicana leaf extract and evaluation of their antimicrobial activities. Dig J Nanomater and Biostruct. 2010;5(2):3-9.
25
26.Mohanty S, Jena P, Mehta R, Pati R, Banerjee B, Patil S, et al. Cationic antimicrobial peptides and biogenic silver nanoparticles kill mycobacteria without eliciting DNA damage and cytotoxicity in mouse macrophages. Antimicrob Agents Chemother. 2013;57(8):88-98.
26
ORIGINAL_ARTICLE
CuO-NiO Nano composites: Synthesis, Characterization, and Cytotoxicity evaluation
Objective(s): In this work, CuO- NiO nano-composites were synthesized via free-surfactant co-precipitation method and then their physiochemical properties, as well as cytotoxicity and antifungal effects, were studied. Methods: The structural and optical properties of CuO-NiO nanostructures were analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM), Atomic force microscope (AFM), UV–Vis absorption, and vibrating sample magnetometer (VSM) techniques. MTT assay was used to evaluate the cytotoxicity of nanostructures. Results: The cubical structure of CuO- NiO nano-composites was confirmed by the XRD technique. The optical study of the samples by UV-Vis indicted a blue shift in absorption wavelength with decreasing particle size due to quantum size effect. The super magnetic behavior of CuO-NiO nano composites after calcination was confirmed by magnetic characterization instrument. Finally, the results of cytotoxicity evaluation of CuO-NiO nano-composites at the lower concentrations on Breast cancer MDA cell lines demonstrate no significant toxicity. Minimum inhibitory concentration range and Minimum fungicidal concentration of nanoparticle were determined 0.97-15.62, 7.81µg/ml and for fluconazole were 1.75-25 µg/ml and 12.58 µg/ml, respectively. Conclusions: The study result of antimicrobialof CuO-NiO nano composites indicated an MIC90 antifungal activity with a concentration of 3.90µg/ml against vaginal isolates of C. albicans. The results of cytotoxicity study of nano-composites at concentration of 50µg/ml and 10µg/ml on the cell line of Breast cancer MDA was equivalent to %60 and %80, respectively.
https://www.nanomedicine-rj.com/article_24936_7ad37434d60d7bb3a13ce2e14b03b81b.pdf
2017-04-01
78
86
10.22034/nmrj.2017.56956.1057
Nano-composites
Cytotoxicity
Antifungal
Abbas
Rahdar
a.rahdar@uoz.ac.ir
1
Departments of Physics, Faculty of Science, University of Zabol, Zabol, Iran P.O.Box: 98155-987, Iran
LEAD_AUTHOR
Mousa
Aliahmad
m.aliahnad@usb.ac.ir
2
Department of Physics, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran
LEAD_AUTHOR
Yahya
Azizi
m.heidarimokarrar@gmail.com
3
Department of Physics, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran
AUTHOR
Nasser
Keikha
nasserkeikha@yahoo.com
4
Infectious Disease and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
AUTHOR
Mahdiyeh
Moudi
mahdiyehmodi@yahoo.com
5
Infectious Disease and Tropical Medicine Research Center, Zahedan University of Medical Sciences, Zahedan, Iran
AUTHOR
Farshid
Keshavarzi
kashavarzifarshid@gmail.com
6
Department of Clinical Biochemistry, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
AUTHOR
1.Singh N, Manshian B, Jenkins GJ, Griffiths SM, Williams PM, Maffeis TG, Wright CJ, Doak SH. NanoGenotoxicology: the DNA damaging potential of engineered nanomaterials. Biomaterials. 2009;30:3891-914.
1
2.Pei L, Zhang X, Zhang L, Zhang Y, Xu Y. Solvent influence on the morphology and supercapacitor performance of the nickel oxide. Mater. Lett. 2016;162:238-41.
2
3.Mahato TH, Singh B, Srivastava AK, Prasad GK, Srivastava AR, Ganesan K, Vijayaraghavan R. Effect of calcinations temperature of CuO nanoparticle on the kinetics of decontamination and decontamination products of sulphur mustard. J. Hazard. Mater. 2011;192:1890-5.
3
4.Gajendiran J, Rajendran V. Synthesis and characterization of coupled semiconductor metal oxide (ZnO/CuO) nanocomposite. Mater. Lett. 2014;116:311-3.
4
5.Gajendiran J, Ramamoorthy C, Sankar KP, Kingsly TR, Kamalakannan V, Krishnamoorthy T. Optical and Luminescent Properties of NiO-CuO Nanocomposite by The Precipitation Method. J.Advanc Chem Sci, 2016;227-9.
5
6. Solanki PR, Kaushik A, Agrawal VV, Malhotra BD. Nanostructured metal oxide-based biosensors. NPG Asia Mater. 2011;3:17-24.
6
7.Ghanbari K, Babaei Z. Fabrication and characterization of non-enzymatic glucose sensor based on ternary NiO/CuO/polyaniline nanocomposite. Anal. Biochem. 2016;498:37-46.
7
8.Hassanpour M, Safardoust H, Ghanbari D, Salavati-Niasari M. Microwave synthesis of CuO/NiO magnetic nanocomposites and its application in photo-degradation of methyl orange. J. Mater. Sci-Mater. El. 2016;27:2718-27.
8
9.Said AE, El-Wahab MM, Soliman SA, Goda MN. Synthesis and Characterization of Nano CuO-NiO Mixed Oxides. Nanosci. Nanotechnol. 2014;2:17-28.
9
10.Lenggoro IW, Itoh Y, Iida N, Okuyama K. Control of size and morphology in NiO particles prepared by a low-pressure spray pyrolysis. Mater Res. Bull. 2003;38:1819-27.
10
11.Ma CL, Sun XD. Preparation of nanocrystalline metal oxide powders with the surfactant-mediated method. Inorg Chem. Commun. 2002;5:751-5.
11
12.Wang CB, Gau GY, Gau SJ, Tang CW, Bi JL. Preparation and characterization of nanosized nickel oxide. Catal. Lett. 2005;101:241-7.
12
13.Tao D, Wei F. New procedure towards size-homogeneous and well-dispersed nickel oxide nanoparticles of 30 nm. Mater. Lett. 2004;58:3226-8.
13
14.Wang Y, Ke JJ. Preparation of nickel oxide powder by decomposition of basic nickel carbonate in microwave field with nickel oxide seed as a microwave absorbing additive. Mater. Res. Bull. 1996;31:55-61.
14
15.Illy-Cherrey S, Tillement O, Dubois JM, Massicot F, Fort Y, Ghanbaja J, Bégin-Colin S. Synthesis and characterization of nano-sized nickel (II), copper (I) and zinc (II) oxide nanoparticles. Mater. Sci Eng.A . 2002;338:70-5.
15
16.Li C, Zhang D, Liu X, Han S, Tang T, Han J, Zhou C. Chemical capping synthesis of nickel oxide nanoparticles and their characterizations studies. Appl Phys Lett .2003;82: 1613.
16
17.Theivasanthi T, Venkadamanickam G, Palanivelu M, Alagar M. Nano sized Powder of Jackfruit Seed: Spectroscopic and Anti-microbial Investigative Approach. Nano Biomed Eng. 2011;3:1-6.
17
18.Rahdar A, Aliahmad M, Asnaashari H. Effect of Different Capping Agents on the Undoped ZnS Semiconductor Nanocrystals: Synthesis and Optical and Structural Characterization. Adv. Sci. Lett. 2013;19:547-9.
18
19.Rahdar A, Aliahmad M, Azizi Y. NiO Nanoparticles: Synthesis and Characterization. J. Nanostruct. 2015;5:145-51.
19
20.Pankhurst QA, Connolly J, Jones SK, Dobson JJ. Applications of magnetic nanoparticles in biomedicine. J. Phys. D: Appl. Phys. 2003;36:R167.
20
21.Tauc J. Optical Properties of Solids, New York: Academic Press Inc;1966.
21
22.Rahdar A, Aliahmad M, Azizi Y. Synthesis of Cu Doped NiO Nanoparticles by Chemical Method. J Nanostruct. 2014;4:145-52.
22
23.Hartley PA, Parfitt GD, Pollack LB. The role of the van der Waals force in the agglomeration of powders containing submicron particles. Power Tech. 1985;42:35-46.
23
24.Kumar S, Kim YJ, Koo BH, Lee CG. Structural and magnetic properties of Ni doped CeO2 nanoparticles. J Nanosci Nanotechnol. 2010;10:7204-7.
24
25.Aliahmad M, Rahdar A, Sadeghfar F, Bagheri S, Hajinezhad MR. Synthesis and Biochemical effects of magnetite nanoparticle by surfactant-free electrochemical method in an aqueous system: The current density effect. Nanomed Res J. 2016;1:39-46.
25
26.Hwang JH, Dravid VP, Teng MH, Host JJ, Elliott BR, Johnson DL, Mason TO. Magnetic properties of graphitically encapsulated nickel nanocrystals. J. Mater. Res. 1997;12:1076-82.
26
27.Stockert JC, Blázquez-Castro A, Cañete M, Horobin RW, Villanueva Á. MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets. Acta histochemica. 2012;114:785-96.
27
28.Marshall NJ, Goodwin CJ, Holt SJ. A critical assessment of the use of microculture tetrazolium assays to measure cell growth and function. Growth Regul, 1995;5:69-84.
28
29.Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983;65:55-63.
29
30.Pfaller MA, Chaturvedi V, Espinel-Ingroff A, Ghannoum MA, Gosey LL, Odds FC, Rex JH, Rinaldi MG, Sheehan DJ, Walsh TJ, Warnock DW. National Committee for Clinical Laboratory Standards, reference method for broth dilution antifungal susceptibility testing of yeasts. NCCLS Document M27eMA2 NCCLS. Pennsylvania, USA. 2002.
30
31.Saadat E, Amini M, Dinarvand R, Dorkoosh FA. Polymeric micelles based on hyaluronic acid and phospholipids: Design, characterization, and cytotoxicity. Inc. J. Appl. Polym. Sci. 2014;131.
31
32.Khoshnevisan K, Barkhi M, Ghasemzadeh A, Tahami HV, Pourmand S. Fabrication of Coated/Uncoated Magnetic Nanoparticles to Determine Their Surface Properties. Mater. Manuf. Process. 2016;31:1206-15.
32
33.Moses SL, Edwards VM, Brantley E. Cytotoxicity in MCF-7 and MDA-MB-231 Breast Cancer Cells, without Harming MCF-10A Healthy Cells. J Nanomed Nanotechnol. 2016;7: 2.
33
34.Ghahremanloo A, Rajabi O, Ghazvini K, Mirmortazavi A, MOTEVALI HM. Antifungal effect of silver nanoparticles in acrylic resins. Antifungal Effect of Silver Nanoparticles in Acrylic Resins. J Mash Dent Sch. 2013; 37:239-248.
34
35.Alipoor J, Madani M, Naghsh N, Bayat M. Investigation of the Effect of Gold Nanoparticles on Vital Factors of Isolated Candida albicans in Patients with Vulvovaginal Candidiasis In Vitro. J.Ardabil.Univ.Med.Sci. 2015;15:179-88.
35
36.Mahmoodi NM, Hosseinabadi-Farahani Z, Bagherpour F, Khoshrou MR, Chamani H, Forouzeshfar F. Synthesis of CuO–NiO nanocomposite and dye adsorption modeling using artificial neural network. Desalin.Water Treat. 2016;57:17220-9.
36
37.Devadathan D, Raveendran R. Polyindole based nickel-zinc oxide nanocomposite-characterization and antifungal studies. Int J Chem Eng Appl. 2014;5:240.
37
38.Alijanian Z, Talebian N, Doudi M. Bactericidal Activity of Copper Oxide Nanocomposite/Bioglass for in Vitro Clindamycin Release in Implant Infections Due to Staphylococcus aureus. Avicenna j. med. biochem. 2016;4:1-10.
38
39.KS US, Govindaraju K, Kumar G, Prabhu D, Arulvasu C, Karthick V, Changmai N. Anti-proliferative effect of biogenic gold nanoparticles against breast cancer cell lines (MDA-MB-231 & MCF-7). Appl. Surf. Sci. 2016;371:415-24.
39
40.Abbasalipourkabirreh R, Salehzadeh A, Abdullah R. Cytotoxicity effect of solid lipid nanoparticle on human breast cancer cell lines. Biotechnology. 2011;10:528-33.
40
41.Hemmati M, Ghasemzadeh A, Haji Malek-kheili M, Khoshnevisan K, Koohi MK. Investigation of acute dermal irritation/corrosion, acute inhalation toxicity and cytotoxicity tests for Nanobiocide®. Nanomed Res J. 2016;1:23-9.
41
ORIGINAL_ARTICLE
Electrospinning of Polyacrylonitrile Nanofibers and Simulation of Electric Field via Finite Element method
Objective(s): Since the electric field is the main driving force in electrospinning systems, the modeling and analysis of electric field distribution are critical to the nanofibers production. The aim of this study was modeling of the electric field and investigating the various parameters on polyacrylonitrile (PAN) nanofibers morphology and diameter. Methods: The electric field profile at the nozzle and electrospinning zone was evaluated by Finite Element Method. The morphology and diameter of nanofibers were examined by Scanning electron microscopy (SEM). Results: The results of the electric field analysis indicated that the electric field was concentrated at the tip of the nozzle. Moreover, in the spinning direction, the electric field was concentrated at the surface of the spinneret and decayed rapidly toward the surface of the collector. Increasing polymer solution concentration from 7 to 11wt.% led to increasing nanofibers diameter form 77.76 ± 19.44 to 202.42 ± 36.85. Conclusions: Base on our results, it could be concluded that concentration of the electric field at the tip of the nozzle is high and initiates jet and nanofibers formation. PAN nanofibers can be transformed to carbon nanofibers which have various applications in biomedicine.
https://www.nanomedicine-rj.com/article_25014_35fb120a050074e149432447bdd5e52c.pdf
2017-04-01
87
92
10.22034/nmrj.2017.57231.1060
Polyacrylonitrile Nanofibers
Electrospinning
Electric field profile
finite element method
Hadi
Samadian
h30samadiyan@gmail.com
1
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
AUTHOR
Hamid
Mobasheri
h.mobasheri@ut.ac.ir
2
Laboratory of Membrane Biophysics and Macromolecules, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.
AUTHOR
Saeed
Hasanpour
s.hasanpour66@yahoo.com
3
Laser and Plasma Research Institute, University of ShahidBeheshti, Tehran, Iran.
AUTHOR
Reza
Faridi Majidi
refaridi@sina.tums.ac.ir
4
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences (TUMS), Tehran, Iran.
LEAD_AUTHOR
1.Garcia-Gomez NA, Garcia-Gutierrez DI, Sepulveda-Guzman S, Sanchez EM. Enhancement of electrochemical properties on TiO2/carbon nanofibers by electrospinning process. J. Mater. Sci. - Mater. Electron.. 2013;24(10):3976-84.
1
2.Adabi M, Saber R, Naghibzadeh M, Faridbod F, Faridi-Majidi R. Parameters affecting carbon nanofiber electrodes for measurement of cathodic current in electrochemical sensors: an investigation using artificial neural network. RSC Adv. 2015;5(99):81243-52.
2
3.Sadri M, Mohammadi A, Hosseini H. Drug release rate and kinetic investigation of composite polymeric nanofibers. Nanomed Res J. 2016;1(2):112-21.
3
4.Boroumand S, Hosseini S, Salehi M, Faridi Majidi R. Drug-loaded electrospun nanofibrous sheets as barriers against postsurgical adhesions in mice model. Nanomed Res J. 2017;2(1):64-72.
4
5.Fang J, Niu H, Lin T, Wang X. Applications of electrospun nanofibers. Chin. Sci. Bull. 2008;53(15):2265.
5
6.Rajzer I, Menaszek E, Castano O. Electrospun polymer scaffolds modified with drugs for tissue engineering. Mater. Sci. Eng., C. 2017.
6
7.Chalco-Sandoval W, Fabra MJ, López-Rubio A, Lagaron JM. Use of phase change materials to develop electrospun coatings of interest in food packaging applications. J. Food Eng. 2017;192:122-8.
7
8.Li H, Williams GR, Wu J, Lv Y, Sun X, Wu H, et al. Thermosensitive nanofibers loaded with ciprofloxacin as antibacterial wound dressing materials. Int. J. Pharm. 2017;517(1):135-47.
8
9.Mano F, Martins M, Sá-Nogueira I, Barreiros S, Borges JP, Reis RL, et al. Production of Electrospun Fast-Dissolving Drug Delivery Systems with Therapeutic Eutectic Systems Encapsulated in Gelatin. AAPS PharmSciTech. 2017:1-7.
9
10.Alkhalaf S, Ranaweera C, Kahol P, Siam K, Adhikari H, Mishra S, et al. Electrochemical energy storage performance of electrospun CoMn 2 O 4 nanofibers. J. Alloys Compd. 2017;692:59-66.
10
11.Piacentini E, Yan M, Giorno L. Development of enzyme-loaded PVA microspheres by membrane emulsification. J. Membr. Sci. 2017;524:79-86.
11
12.Ramakrishna S, Fujihara K, Teo W-E, Yong T, Ma Z, Ramaseshan R. Electrospun nanofibers: solving global issues. Mater. Today. 2006;9(3):40-50.
12
13.McCann JT, Li D, Xia Y. Electrospinning of nanofibers with core-sheath, hollow, or porous structures. J. Mater. Chem. 2005;15(7):735-8.
13
14.Shim WG, Kim C, Lee JW, Yun JJ, Jeong YI, Moon H, et al. Adsorption characteristics of benzene on electrospun‐derived porous carbon nanofibers. J. Appl. Polym. Sci. 2006;102(3):2454-62.
14
15.Madhugiri S, Sun B, Smirniotis PG, Ferraris JP, Balkus KJ. Electrospun mesoporous titanium dioxide fibers. Microporous Mesoporous Mater. 2004;69(1):77-83.
15
16.Sun Z, Zussman E, Yarin AL, Wendorff JH, Greiner A. Compound core–shell polymer nanofibers by co‐electrospinning. Adv. Mater. 2003;15(22):1929-32.
16
17.Ketabchi N, Naghibzadeh M, Adabi M, Esnaashari SS, Faridi-Majidi R. Preparation and optimization of chitosan/polyethylene oxide nanofiber diameter using artificial neural networks. NEURAL. COMPUT. APPL. 2016:1-13.
17
18.Gheibi A, Khoshnevisan K, Ketabchi N, Derakhshan MA, Babadi AA. Application of Electrospun Nanofibrous PHBV Scaffold in Neural Graft and Regeneration: A Mini-Review. Nanomed Res J. 2016;1(2):107-11.
18
19.Deitzel JM, Kleinmeyer J, Harris D, Tan NB. The effect of processing variables on the morphology of electrospun nanofibers and textiles. Polym. J. 2001;42(1):261-72.
19
20.Eda G, Shivkumar S. Bead‐to‐fiber transition in electrospun polystyrene. J. Appl. Polym. Sci. 2007;106(1):475-87.
20
21.Yang Q, Li Z, Hong Y, Zhao Y, Qiu S, Wang C, et al. Influence of solvents on the formation of ultrathin uniform poly (vinyl pyrrolidone) nanofibers with electrospinning. J. Polym. Sci., Part B: Polym. Phys. 2004;42(20):3721-6.
21
22.Yuan X, Zhang Y, Dong C, Sheng J. Morphology of ultrafine polysulfone fibers prepared by electrospinning. Polym. Int. 2004;53(11):1704-10.
22
23.Ki CS, Baek DH, Gang KD, Lee KH, Um IC, Park YH. Characterization of gelatin nanofiber prepared from gelatin–formic acid solution. Polym. J. 2005;46(14):5094-102.
23
24.Adabi M, Saber R, Faridi-Majidi R, Faridbod F. Performance of electrodes synthesized with polyacrylonitrile-based carbon nanofibers for application in electrochemical sensors and biosensors. Mater. Sci. Eng., C 2015;48:673-8.
24
25.Mirzaei E, Amani A, Sarkar S, Saber R, Mohammadyani D, Faridi‐Majidi R. Artificial neural networks modeling of electrospinning of polyethylene oxide from aqueous acid acetic solution. J. Appl. Polym. Sci.2012;125(3):1910-21.
25
26.Esnaashari SS, Rezaei S, Mirzaei E, Afshari H, Rezayat SM, Faridi-Majidi R. Preparation and characterization of kefiran electrospun nanofibers. Int. J. Biol. Macromol. 2014;70:50-6.
26
27.Thompson C, Chase G, Yarin A, Reneker D. Effects of parameters on nanofiber diameter determined from electrospinning model. Polym. J.2007;48(23):6913-22.
27
28.Gibson P, Schreuder‐Gibson H, Rivin D. Electrospun fiber mats: transport properties. AlChE J. 1999;45(1):190-5.
28
29.Ziabari M, Mottaghitalab V, Haghi AK. A new approach for optimization of electrospun nanofiber formation process. Korean J. Chem. Eng. 2010;27(1):340-54.
29
30.Zhao S, Wu X, Wang L, Huang Y. Electrospinning of ethyl–cyanoethyl cellulose/tetrahydrofuran solutions. J. Appl. Polym. Sci. 2004;91(1):242-6.
30
ORIGINAL_ARTICLE
Investigation of hematotoxic effect of nano ZnO, nano Fe3O4 and nano SiO2 in vitro
Objective(s): Evaluation of nanomaterials interaction with blood ingredients is a part of preclinical risk assessment of newly-synthesized materials, especially for nano-sized pharmaceuticals which are intravenously administrated. The red blood cells (RBCs) are susceptible to oxidative stress damage. This study was designed to evaluate induced oxidative hematotoxic effect of nano ZnO, Fe3O4, and nano SiO2 on human red blood cells in vitro. Methods: Blood samples were collected from healthy male volunteers. RBCs were exposed to different concentrations (50, 100, 250mg/ml) of nano ZnO, nano Fe3O4, and nano SiO2 at 4°C for 24hours. Lipid peroxidation and intracellular Glutathione (GSH) level were studied as the biomarkers of oxidative stress. Results: The results showed that the lipid peroxidation had significantly increased. However, after exposure to nanoparticles, the GSH level of RBCs considerably decreased compared to the controls (p
https://www.nanomedicine-rj.com/article_25344_0707765de87c69eb6d1fb2b01aed5e17.pdf
2017-04-01
93
99
10.22034/nmrj.2017.61955.1064
Hematotoxic
Nano ZnO
Nano Fe3O4
Cristobalit
Red blood cells
Mohammad Kazem
Koohi
mkkoohi@ut.ac.ir
1
Department of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran.
AUTHOR
Marzie
Hejazy
mhejazy@ut.ac.ir
2
Basic Science Department, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
LEAD_AUTHOR
Davood
Najafi
d.najafi405@gmail.com
3
Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
AUTHOR
Seyed Mehdi
Sajadi
sajadimehdi9@gmail.com
4
Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
AUTHOR
1.Dobrovolskaia MA, Clogston JD, Neun BW, Hall JB, Patri AK, McNeil SE. Method for analysis of nanoparticle hemolytic properties in vitro. Nano let. 2008; 8(8):2180.
1
2.Xia T, Kovochich M, Brant J, Hotze M, Sempf J, Oberley T, Sioutas C, Yeh JI, Wiesner MR, Nel AE. Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm. Nano let. 2006; 9;6(8):1794-807.
2
3.Neun BW, Dobrovolskaia MA. Method for analysis of nanoparticle hemolytic properties in vitro. Characterization of Nanoparticles Intended for Drug Delivery. 2011;215-24.
3
4.Finaud J, Lac G, Filaire E. Oxidative stress. Sport med. 2006; 1:36(4):327-58.
4
5.Salar-Amoli J, Hejazy M, Esfahani TA. Comparison between some oxidative Stress Biomarkers values in serum and plasma of clinically healthy adult camels (Camelus dromedarius) in Iran. Vet res com. 2009; 1;33(8):849.
5
6.Ghezzi P, Bonetto V, Fratelli M. Thiol–disulfide balance: from the concept of oxidative stress to that of redox regulation. Antioxid Redox Signal. 2005; 1;7(7-8):964-72.
6
7.Joy G. Mohanty, Enika Nagababu, and Joseph M. Rifkind. Red blood cell oxidative stress impairs oxygen delivery and induces red blood cell aging. 2014; 5: 84.
7
8.Mansour SA, Mossa AT. Lipid peroxidation and oxidative stress in rat erythrocytes induced by chlorpyrifos and the protective effect of zinc. Pesticide Biochem Physiol. 2009; 31;93(1):34-9.
8
9.Ruiz A, Morais PC, De Azevedo RB, Lacava ZG, Villanueva A, del Puerto Morales M. Magnetic nanoparticles coated with dimercaptosuccinic acid: development, characterization, and application in biomedicine. J Nanopart Res. 2014; 1;16(11):2589.
9
10.Zhu MT, Feng WY, Wang B, Wang TC, Gu YQ, Wang M, Wang Y, Ouyang H, Zhao YL, Chai ZF. Comparative study of pulmonary responses to nano-and submicron-sized ferric oxide in rats. Toxicol. 2008; 21;247(2):102-11.
10
11.Ali L, Gutiérrez M, Cornudella R, Moreno JA, Piñol R, Gabilondo L, Millán A, Palacio F. Hemostasis disorders caused by polymer coated iron oxide nanoparticles. J biomed nanotech. 2013 ; 1;9(7):1272-85.
11
12.Mayer A, Vadon M, Rinner B, Novak A, Wintersteiger R, Fröhlich E. The role of nanoparticle size in hemocompatibility. Toxicol. 2009; 28;258(2):139-47.
12
13.Wang G, Inturi S, Serkova NJ, Merkulov S, McCrae K, Russek SE, Banda NK, Simberg D. High-relaxivity superparamagnetic iron oxide nanoworms with decreased immune recognition and long-circulating properties. ACS nano. 2014; 23;8(12):12437.
13
14.Ruiz A, Ali LM, Cáceres-Vélez PR, Cornudella R, Gutiérrez M, Moreno JA, Piñol R, Palacio F, Fascineli ML, de Azevedo RB, Morales MP. Hematotoxicity of magnetite nanoparticles coated with polyethylene glycol: in vitro and in vivo studies. Toxicol Res. 2015;4(6):1555-64.
14
15.Vandebriel RJ, De Jong WH. A review of mammalian toxicity of ZnO nanoparticles. Nanotechnol Sci Appl. 2012; 15;5:61-71.
15
16.Zhang, F.F., Wan, Q., Li, C.X., Wang, X.L., Zhu, Z.Q., Xian, Y.Z., Jin, L.T.,Yamamoto, K. Simultaneous assay of glucose, lactate, L –glutamate and hypoxanthine levels in a rat striatum using enzyme electrodes based on neutral red-doped silica nanoparticles. Anal. Bioanal. Chem. 2004;380,637–642.
16
17.Trillaud H, Grenier N, Degreze P, Louail C, Chambon C, Franconi JM. First-pass evaluation of renal perfusion with TurboFLASH MR imaging and superparamagnetic iron oxide particles. J Magn Reson Imaging. 1993; 3: 83–91
17
18.Wang F, Gao F, Lan M, Yuan H, Huang Y, Liu J. Oxidative stress contributes to silica nanoparticle-induced cytotoxicity in human embryonic kidney cells. Toxicology in vitro. 2009;31;23(5):808-15.
18
19.Sharma V, Singh P, Pandey AK, Dhawan A. Induction of oxidative stress, DNA damage and apoptosis in mouse liver after sub-acute oral exposure to zinc oxide nanoparticles. Mut Res/Genetic Toxicol Environ Mut. 2012; 14;745(1):84-91.
19
20.Ye Y, Liu J, Xu J, Sun L, Chen M, Lan M. Nano-SiO 2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cell line. Toxicol in Vitro. 2010;30;24(3):751-8.
20
21.Becker S, Soukup JM, Gallagher JE. Differential particulate air pollution induced oxidant stress in human granulocytes, monocytes and alveolar macrophages. Toxicol in vitro. 2002;30;16(3):209-18.
21
22.Peters K, Unger RE, Gatti AM, Sabbioni E, Tsaryk R, Kirkpatrick CJ. Metallic nanoparticles exhibit paradoxical effects on oxidative stress and pro-inflammatory response in endothelial cells in vitro. Int J Immunopathol Pharmacol. 2007; 20(4):685-95.
22
23.Pulskamp K, Diabaté S, Krug HF. Carbon nanotubes show no sign of acute toxicity but induce intracellular reactive oxygen species in dependence on contaminants. Toxicol let. 2007; 10;168(1):58-74.
23
24.Park EJ, Park K. Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro. Toxicol lett. 2009; 10;184(1):18-25.
24
25.Trillaud H, Grenier N, Degreze P, Louail C, Chambon C, Franconi JM. First-pass evaluation of renal perfusion with TurboFLASH MR imaging and superparamagnetic iron oxide particles. J Magn Reson Imaging. 1993; 3: 83–91
25
26.Lin XL, Zhao SH, Zhang L, Hu GQ, Sun ZW, Yang WS. Dose-dependent cytotoxicity and oxidative stress induced by “naked” Fe3O4 Nanoparticles in human hepatocyte. Chem Res Chin Univ. 2012; 28:114-8.
26
27.Watanabe M, Yoneda M, Morohashi A, Hori Y, Okamoto D, Sato A, Kurioka D, Nittami T, Hirokawa Y, Shiraishi T, Kawai K. Effects of Fe3O4 magnetic nanoparticles on A549 cells. Int J mol sci. 2013; 25;14(8):15546-60.
27
28.Lin BL, Shen XD, Cui S. Application of nanosized Fe3O4 in anticancer drug carriers with target-orientation and sustained-release properties. Biomed Mater. 2007; 3;2(2):132.
28
29.Ahamed M, A Alhadlaq H, Alam J, Khan M, Ali D, Alarafi S. Iron oxide nanoparticle-induced oxidative stress and genotoxicity in human skin epithelial and lung epithelial cell lines. Curr pharm des. 2013; 1;19(37):6681-90.
29
30.Lin W, Huang YW, Zhou XD, Ma Y. In vitro toxicity of silica nanoparticles in human lung cancer cells. Toxicol appl pharmacol. 2006; 15;217(3):252-9.
30
31.Chang JS, Chang KL, Hwang DF, Kong ZL. In vitro cytotoxicitiy of silica nanoparticles at high concentrations strongly depends on the metabolic activity type of the cell line. Environ Sci Tech. 2007 ; 15;41(6):2064-8.
31
32.Zhang Y, R Nayak T, Hong H, Cai W. Biomedical applications of zinc oxide nanomaterials. Curr mol med. 2013; 1;13(10):1633-45.
32
33.Ahamed M, Akhtar MJ, Raja M, Ahmad I, Siddiqui MK, AlSalhi MS, Alrokayan SA. ZnO nanorod-induced apoptosis in human alveolar adenocarcinoma cells via p53, survivin and bax/bcl-2 pathways: role of oxidative stress. Nanomedicine: Nanotech, Biol Med. 2011; 31;7(6):904-13.
33
34.Huang CC, Aronstam RS, Chen DR, Huang YW. Oxidative stress, calcium homeostasis, and altered gene expression in human lung epithelial cells exposed to ZnO nanoparticles. Toxicol in vitro. 2010;28;24(1):45-55.
34
35.Osmond MJ, Mccall MJ. Zinc oxide nanoparticles in modern sunscreens: an analysis of potential exposure and hazard. Nanotoxicol. 2010; 1;4(1):15-41.
35
36.Kim, Y. H., Fazlollahi, F., Kennedy, I. M., Yacobi, N. R., Hamm-Alvarez, S. F., Borok, Z., & Crandall, E. D. Alveolar epithelial cell injury due to zinc oxide nanoparticle exposure. Am J Respir&crit care med. 2010;182(11), 1398-1409.
36
37.Şentürk ÜK, Gündüz F, Kuru O, Aktekin MR, Kipmen D, Yalçin Ö, Bor-Küçükatay M, Yeşilkaya A, Başkurt OK. Exercise-induced oxidative stress affects erythrocytes in sedentary rats but not exercise-trained rats. J Appl Physiol. 2001; 1;91(5):1999-2004.
37
38.Hoffer LJ, Levine M, Assouline S, Melnychuk D, Padayatty SJ, Rosadiuk K, Rousseau C, Robitaille L, Miller WH. Phase I clinical trial of iv ascorbic acid in advanced malignancy. Ann Oncol. 2008; mdn377.
38
ORIGINAL_ARTICLE
Preparation and characterization of CS/ PEO/ cefazolin nanofibers with in vitro and in vivo testing
Objective(S): Electrospinning of chitosan/polyethylene oxide (CS/PEO) nanofibers with the addition of cefazolin to create nanofibers with antimicrobial properties were examined. Methods: Polymeric nanofibers including CS/PEO and CS/PEO /cefazolin, were produced by electrospinning method. The range of nanofiber was 60-100 nm in diameter and measured with ImageJ software. The morphology of electrospun nanofibers was studied with use of scanning electron microscopy (SEM). Moreover, the chemical structures of the nanofibers were evaluated by FT-IR. The drug release of nanofibers was also investigated by UV-Vis spectrophotometry. The antibacterial activity of scaffolds was tested by two type bacteria including Escherichia coli and Staphylococcus aureus. The healing ability of nanofibers was studied on the rat’s wound. Results: The SEM images indicated that the addition of cefazolin as much as 1wt% brings about the best nanofiber. Also, the morphology of electrospun nanofiber is dependent on the viscosity of the solution and the ratio of CS /PEO/cefazolin. According to the results of cefazolin releasing from nanofibers, the best results were obtained in the presence of CS /PEO/1wt%cefazolin nanofibers as healing sample. In animal studies, the effect of nanofibers was studied in the burn wound healing of rats and improvement of the wound was observed by nanofibers containing 1%wt cefazolin. Conclusions: According to these results, it seems that CS /PEO/1wt% cefazolin nanofiber is a good choice as a wound covering agent and hold more moisture in its structure thus the surface of wound remain wet during the healing process that prevent from nanofiber sticking to the wound surface.
https://www.nanomedicine-rj.com/article_25345_b25ceba5ce7602f95cdc25bb317a0265.pdf
2017-04-01
100
110
10.22034/nmrj.2017.59850.1061
Chitosan
Polymer composites
Biocompatible polymers
Cefazolin
Nanofibers
Minoo
Sadri
mnsadri@yahoo.com
1
Department of Biochemistry and Biophysics, Education and Research Center of Science and Biotechnology, Malek Ashtar University of Technology, Tehran, Iran
LEAD_AUTHOR
Saede
Arab Sorkhi
arabsaede@yahoo.com
2
Department of Biochemistry and Biophysics, Education and Research Center of Science and Biotechnology, Malek Ashtar University of Technology, Tehran, Iran
AUTHOR
1.Reneker DH, Yarin AL, Fong H, Koombhongse S. Bending instability of electrically charged liquid jets of polymer solutions in electrospinning. J Appl Phys. 2000;87:4531– 47.
1
2.Kumar MN. A review of chitin and chitosan applications. React Funct Polym. 2000;46:1-27.
2
3.Matthews JA, Wnek GE, Simpson DG, Bowlin GL. Electrospinning of collagen nanofibers. Biomacromolecules. 2002; 3: 232–8.
3
4.Hirano S, Itakura C, Seino H, Akiyama Y, Nonaka I, Kanbara N, Kawakami T.Chitosan as an ingredient for domestic animal feeds. J Agric Food Chem. 1990; 38:1214–7.
4
5.Aiedehe K, Gianasii E, Orienti I, Zecchi V. Chitosan microcapsules as controlled release systems for insulin. J Microencapsul. 1997;14: 567–76.
5
6.Berger J, Reist M, Mayer JM, Felt O, Gurny R. Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications. Eur J Pharm Biopharm. 2004; 57:35–52.
6
7.Michibayashi N, Kurikawa N, Nakashima Y, Mizoguchi T, Harada A, Higashiyama S, Muranaka H, Kawase M.Effectiveness of fructose-modified chitosan as a scaffold for hepatocyte attachment. Biol Pharm Bull. 1997; 20:1290–4.
7
8.Zhang Y, Zhang M. Synthesis and characterization of macroporous chitosan/calcium phosphate composite scaffolds for tissue engineering. J Biomed Mater Res. 2001;55 :304–12.
8
9.Park YJ, Lee YM, Park SN, Sheen SY, Chung CP, Lee SJ. Platelet derived growth factor releasing chitosan sponge for periodontal bone regeneration. Biomaterials. 2000; 21:153–9.
9
10.Gutowska A, Jeong B, Jasionowski M. Injectable gels for tissue engineering. Anat Rec. 2001; 263:342–9.
10
11.Klokkevold PR, Vandemark L, Kenney EB, Bernard GW. Osteogenesis enhanced by chitosan (poly-N-acetyl glucosaminoglycan) in vitro. J Periodontol. 1996; 67:1170–5.
11
12.Malette WG, Quigley Jr HJ, Adickes ED. Chitosan effect in vascular surgery, tissue culture and tissue regeneration. In ‘Chitin in Nature and Technology’ (eds. Muzzarelli R, Jeuniaux C , Gooday G W ) Plenum Press, New York, 1986;435–442.
12
13.Ohkawa K, Cha D, Kim H, Nishida A, Yamamoto H. Electrospinning of Chitosan. Macromolecul Rapid Commun. 2004; 25:1600–5.
13
14.Duan B, Dong C, Yuan X, Yao K. Electrospinning of chitosan solutions in acetic acid with poly (ethylene oxide). J Biomater Sci Polym Ed. 2004;15:797–811.
14
15.Huang ZM, Zhang YZ, Kotaki M, Ramakrishna S. A review on polymer nanofibers by electrospinning and their applications in nanocomposites. Compos Sci Technol. 2003; 63:2223–53.
15
16.Jiang H, Fang D, Hsiao BS, Chu B, Chen W. Optimization and characterization of dextran membranes prepared by electrospinning. Biomacromolecules. 2004; 5:326–33.
16
17.Khil MS, Cha DI, Kim HY, Kim IS, Bhattarai N. Electrospun nanofibrous polyurethane membrane as wound dressing. J Biomed Mater Res. 2003;67:675–9.
17
18.Costa KD, Lee EJ, Holmes JW. Creating alignment and anisotropy in engineered heart tissue: role of boundary conditions in a model three-dimensional culture system. Tissue Eng. 2003;9: 567–77.
18
19.No HK, Park NY, Lee SH, Meyers SP. Antibacterial activity of chitosans and chitosan oligomers with different molecular weights. Int J Food Microbiol. 2002;74:65-72.
19
20.Bhattarai N, Edmondson D, Veiseh O, Matsen FA, Zhang M. Electrospun chitosan-based nanofibers and their cellular compatibility. Biomaterials. 2005; 26:6176-84.
20
21.Brown G, Chamberlain R, Goulding J, Clarke A. Ceftriaxone versus cefazolin with probenecid for severe skin and soft tissue infections. J Emerg Med. 1996; 14: 547-51.
21
22.Fazli Y, Shariatinia Z. Controlled release of cefazolin sodium antibiotic drug from electrospun chitosan-polyethylene oxide nanofibrous. Mats Mater Sci and Eng C. 2017; 71: 641–52.
22
ORIGINAL_ARTICLE
Magnetic/pH-sensitive nanocomposite hydrogel based carboxymethyl cellulose –g- polyacrylamide/montmorillonite for colon targeted drug delivery
Objective(s): The main aim of current research was to develop a novel magnetically responsive hydrogel by radical polymerization of carboxymethyl cellulose (CMC) on acryl amide (Am) using N,N'-methylene bis acrylamide (MBA) as a crosslinking agent, potassium persulfate (KPS) as a free radical initiator, and magnetic montmorillonite ( mMT) nanoclay as nano-filler. Methods: The new product (CMC-g-Am/mMT) was characterized by FT-IR, XRD, TEM, SEM, and VSM techniques. Drug loading and release efficiency were evaluated by Diclofenac Sodium (DS) as a model drug. Results:SEM results demonstrated that magnetic nanoclay (mMT) can cause a rough morphology. Transmission electron microscopy (TEM) indicated the formation of MNPs into the montmorillonite clay structure with the final average particle size of around 100 nm. Furthermore, according to the in vitro drug release profiles, the maximum cumulative release was around 79% at pH=7.4 under applied magnetic field. Conclusions: The results indicate that the prepared CMC-g-Am/mMT platform can be used for delivery of drugs to the colon by applying an external magnetic field.
https://www.nanomedicine-rj.com/article_25441_04c6cf8aa46f00754b18152d12efe98a.pdf
2017-04-01
111
122
10.22034/nmrj.2017.58964.1058
Carboxymethyl cellulose
Magnetic montmorillonite
Drug release
swelling
Diclofenac sodium
Gholam Reza
Mahdavinia
grmnia@maragheh.ac.ir
1
Labratory for Polymer Research, Department of Chemistry, Faculty of Science, University of Maragheh, Maragheh, Iran
AUTHOR
Ali
Afzali
ali.afzali@yahoo.com
2
Department of Chemistry, University of Payame Noor, West Azerbaijan, Miandoab, Iran
AUTHOR
Hossein
Etemadi
hosseinetemadi39@yahoo.com
3
Labratory for Polymer Research, Department of Chemistry, Faculty of Science, University of Maragheh, Maragheh, Iran
LEAD_AUTHOR
Hossein
Hoseinzadeh
h_hoseinzadeh@pnu.ac.ir
4
Department of Chemistry, University of Payame Noor, West Azerbaijan, Miandoab, Iran
AUTHOR
1.Kozlovskaya V, Zavgorodnya O, Wang Y F, Ankner J, Kharlampieva E. Tailoring Architecture of Nanothin Hydrogels: Effect of layering on pH-triggered swelling. ACS Macro Lett. 2013; (2):226−229.
1
2.Kozlovskaya V, Chen J, Tedjo C, Liang X, Campos-Gomez J, Oh J, Saeed M, Lunguc TC, Kharlampieva E. pH-Responsive Hydrogel Cubes for Release of Doxorubicin in Cancer Cells. J. Mater. Chem. B. 2014; (2): 2494-2507.
2
3.Kumar C S R, Mohammad F. Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery. Adv. Drug Delivery Rev. 2011; (63): 789-808.
3
4.Mahdavinia GR, Etemadi H, Soleymani F. Magnetic/pH-responsive beads based on caboxymethyl chitosan and κ-carrageenan and controlled drug release. Carbohydr Polym. 2015; (128): 112-121.
4
5.Anderson SA, Rader RK, Westlin WF, Null C, Jackson D, Lanza C.M, Wickline SA, Kotyk, JJ. Magnetic resonance contrast enhancement of neovasculature with αvβ3-targeted nanoparticles. Magn Reson Med. 2000; 44 (3): 433–439.
5
6.Mahmoudi M, Sant S, Ben W, Laurent S, Tapas S. Superparamagnetic iron oxide nanoparticles (SPIONs): development, surface modification and applications in chemotherapy. Adv. Drug Delivery Rev. 2011; 63(1-2): 24 -46.
6
7.Zhang J, Misra R D K. Magnetic drug-targeting carrier encapsulated with thermosensitive smart polymer: core-shell nanoparticle carrier and drug release response. Acta Biomater. 2007; 3(6): 838-50.
7
8.Galbiati A, Tabolacci C, Morozzo B, Rocca D, Mattioli P, Beninati S, Paradossi G, Desideri A. Targeting Tumor Cells through Chitosan-Folate Modified Microcapsules Loaded with Camptothecin. Bioconjugate Chem. 2011; 22 (6): 1066–1072.
8
9.Hezaveh H, Muhamad I I. Controlled drug release via minimization of burst release in pH-response kappa-carrageenan/polyvinyl alcohol hydrogels. Chem eng res des. 2013; (91):508-519. 10.Choubey Y, BajpaiA. K. Investigation on magnetically controlled delivery of doxorubicin from superparamagnetic nanocarriers of gelatin crossllinked with genipin. J Mater Sci: Mater Med. 2010; (21): 51573–1586.
9
11.Zhu, K.; Yea, T.; Liua J, Peng Z, Xu S, Lei J H D, Li B. Nanogels fabricated by lysozyme and sodium carboxymethyl cellulose for 5-fluorouracil controlled release. Int. J. Pharm. 2013; 441(1): 721-727.
10
12.Lei H, Hongshan L, Liufeng L, Bin L. Green-step assembly of low density lipoprotein/sodium carboxymethyl cellulose nanogels for facile loading and pH-dependent release of doxorubicin. Colloids Surf B Biointerfaces. 2015; (126C): 288-296.
11
13.Butun S, Ince F G, Erdugan H, Sahinera N, One-step fabrication of biocompatible carboxymethyl cellulose polymeric particles for drug delivery systems. Carbohydr Polym. 20112; (86): 636–643.
12
14.Tas C, Ozkan C K, Savaser A, Ozkan Y, Tasdemir U, Altunay H. Nasal administration of metoclopramide from different dosage forms: in vitro, ex vivo, and in vivo evaluation. Drug Deliv. 2009; 16 (3): 167-75.
13
15.Anirudhan T S, Sandeep S, Divya P L. Synthesis and characterization of maleated cyclodextrin-grafted-silylated montmorillonite for the controlled release and colon specific delivery of tetracycline hydrochloride. RSC Adv. 2012; (2): 9555-9564.
14
16. Wen-fu L, Chen Y C. Superabsorbent polymeric materials. XII. Effect of montmorillonite on water absorbency for poly (sodium acrylate) and montmorillonite nanocomposite superabsorbents, J. Appl. Polym. Sci. 2004; 92(5): 3422-3429.
15
17.Farshi Azhar F, Olad A A. study on sustained release formulations for oral delivery of 5-fluorouracil based on alginate–chitosan/montmorillonite nanocomposite systems. Appl clay sci. 2014; (101): 288–296.
16
18.Depan D, Kumar A P, Singh R P, Cell proliferation and controlled drug release studies of nanohybrids based on chitosan-g-lactic acid and montmorillonite. Acta Biomater. 2009; 5 (1): 93-100.
17
19.Lee YH, Kuo T F, Chen BY, Feng YK, Wen Y R, Lin W C, Lin F H. Toxicity assessment of montmorillonite as a drug carrier for pharmaceutical applications: yeast and rats model. Biomed. Eng. Appl. Basis Commun. 2005; 17(2): 12.
18
20.Park J K, Choy Y B, Oh J M, Kim J Y, Hwang S J, Choy J H. Controlled release of donepezil intercalated in smectite clays. Int. J. Pharm. 2008; 359(1-2): 198-204.
19
21.Lin FH, Lee YH, Jian C. H, Wong J. M, Shieh M J, Wang C Y A. study of purified montmorillonite intercalated with 5-fluorouracil as drug carrier, Biomaterials. 2002; 23(9): 1981-7.
20
22.Zheng J P, Luan L, Wang H Y, Xi L F, Yao K D. Study on ibuprofen/montmorillonite intercalation composites as drug release system Appl. Clay Sci. 2007; 36(4): 297–301.
21
23. Mahdavinia G R, Hasanpour S, Leila B, Sheykhloie Hossein. Study on adsorption of Cu(II) on magnetic starch‐g‐ polyamidoxime/montmorillonite/Fe3O4 nanocomposite hydrogelas novel chelating ligands. Starch/Starke. 2016; 68 (3-4):188–199.
22
24.Wu D, Zheng P, Chang P R, Ma X. Preparation and characterization of magnetic rectorite/iron oxide nanocomposite hydrogeland its application for the removal of the dyes. Chem. Eng J. 2011; 174 (1): 489-494.
23
25.Mohapatra DK and Swagatika M. 5-Fluoro Uracil for colon specific drug delivery of a Poly (CarboxyMethyl Cellulose-co-Acryl Amide)/MBA Nano Sized Hydrogel. IJCPS 2012;1 (1) :250-262
24
26.Zhang D, Karki AB, Rutman D, Young D P, Wang A, Cocke D, Ho T. H, Guo Z. Electrospun polyacrylonitrile nanocomposite fibers reinforced with Fe3O4 nanoparticles: Fabrication and property analysis. Polymers. 2009; 50(17):4189–4198.
25
27.Tzitzios V, Basina G, Bakandritsos A, Hadjipanayis C G, Mao H, Niarchos D, Tucek J, Zboril R. Immobilization of magnetic iron oxide nanoparticles on laponite discs-an easy way to iocompatible ferrofluids and ferrogels. J. Mater. Chem. B. 2010; (20): 5418-5428.
26
28.Zixian X, Fengzhu L, Yihe Z, Liling F. Synthesis and characterization of CPC modified magnetic MMT capable of using as anisotropic nanoparticles. Chem. Eng J. 2013; (216): 755-762.
27
29.El-Di N. H. M, AbdAlla S. G, Wahab A, El-Naggar M. Swelling and drug release properties of acrylamide/carboxymethyl cellulose networks formed by gamma irradiation. Radiat phys chem. 2010;79(6):725–730.
28
30.Kolhatkar A G, Jamison C A, Litvinov D, Willson C R, Lee T R. Tuning the Magnetic Properties of Nanoparticles. Int J Mol Sci. 2013; 14(8): 15977–16009.
29
31.Omidian H, Park K, Kandalam U, Rocca J.G. Swelling and Mechanical Properties of Modified HEMA-based Superporous Hydrogels. J. Bioact. Compat. Polym. 2010; (25): 483-497. 32.Li A, Zhang J, Wang A. Preparation and slow-release property of a poly (acrylic acid)/attapulgite/sodium humate superabsorbent composite. J Appl Polym Sci 2007; (103): 37 37–45.
30
33.Darvishi Z, Kabiri K, Zohuriaan-Mehr M J, Morsali A. Nanocomposite super-swelling hydrogels with nanorod bentonite. J Appl Polym Sci. 2011; (120): 3453–3459.
31
34.Cyras V P, Manfredi L B, Ton-That M T, Vázques A. Physical and mechanical properties of thermoplastic starch/montmorillonite nanocomposite films. Carbohydr Polym. 2008; (73): 55–63.
32
35.Almasi H, Ghanbarzadeh B, Entezami A A. Physicochemical properties of starch–CMC–nanoclay biodegradable films. Int. J. Biol. Macromolec. 2010; (46): 1-5.
33
36.Mistsumata T, Suemitsu Y, Fujii K, Fujii T, Taniguchi T. pH respond of chitosan, k-carrageenan and carboxymethyl cellulose sodium salt complex hydrogels. Polymers. 2003; 44(501): 7103-7111.
34
37.Yin Y, Yang Y, Xu H. Swelling behavior of hydrogels for colon-site drug delivery. J Appl Polym Sci. 2002; (83): 2835-2842.
35
38.Schott H. Swelling kinetics of polymers. J macromol sci b. 1992; (31): 1-9.
36
39.Foo K Y, Hameed B H. Insights into the modeling of adsorption isotherm systems. Chem. Eng J. 2010; (156): 2–10.
37
40.Zhang H, Zhai D, He Y. Graphene oxide/polyacrylamide/carboxymethyl cellulose sodium nanocomposite hydrogel with enhanced mechanical strength: preparation, characterization and the swelling behavior. RSC Adv. 2014; (4): 44600-44609.
38
41.Xie M, Shi H, Ma K, Shen H, Li B, Shen S, Wang X, Jin,Y. Hybrid nanoparticles for drug delivery and bioimaging: Mesoporous silica nanoparticles functionalized with carboxyl groups and a near-infrared fluorescent dye. J. Colloid Interface Sci. 2013; (395): 306–314.
39
42.Hu S H, Liu T Y, Huang H Y, Liu D M, Chen S Y. Magnetic-sensitive silica nanospheres for controlled drug release. Langmuir. 2008; (24): 239-244.
40
43.Cypes S H, Saltzman W M, Giannelis E P. Organosilicate-polymer drug delivery systems: controlled release and enhanced mechanical properties. J. Control. Release. 2008; 90(2):163-9.
41
44.Likhitkar S, Bajpai A K. Magnetically controlled release of cisplatin from superparamagnetic starch nanoparticles. Carbohydr Polym. 2012; (87): 300-308.
42
45.Siepmann, J.; Peppas, N. A.: Modeling of drug release from delivery systems based on hydroxypropyl methylcellulose (HPMC). Adv. Drug Delivery Rev. 2001; (48): 139-157.
43
46.Bardajee G R, Hooshyar Z, Asli M J, Shahidi F E, Dianatnejad N. Synthesis of a novel supermagnetic iron oxide nanocomposite hydrogel based on graft copolymerization of poly ((2-dimethylamino) ethyl methacrylate) onto salep for controlled release of drug. Mater Sci Eng C. 2014; (36): 277-286.
44
47.Soppiranth K S, Aminabhavi TM. Water transport and drug release study from cross- linked polyacrylamide grafted guar gum hydrogel microspheres for the controlled release application. Eur. J. Pharm. Biopharm. 2002; (53):87-98.
45
ORIGINAL_ARTICLE
Investigation of chitosan nanoparticles durability in combination with antioxidant-antibacterial fraction extracted from Lactobacillus casei and possible increase of antibacterial activity of the fraction in hybrid nanoparticle
Objective(s): This study considered the combination of chitosan nanoparticles with antioxidant-antibacterial fraction extracted from Lactobacillus casei and investigation of possible increasing of antibacterial activity of the fraction in hybrid nanoparticle and the effect of the fraction on the stability of chitosan nanoparticles. Methods: Extraction of Antioxidant antibacterial material from Lactobacillus casei supernatant was done by thin layer chromatography fractionation. For determination of antioxidant and antibacterial activity of fraction, DPPH (2,2-diphenyl-1-picrylhydrazyl) assay and Minimum Inhibition Concentration (MIC) by micro-well dilution method was used, respectively. For chitosan nanoparticles (Cs NPs) formation, the ionic gelation method was used and the ratio of Tripolyphosphate pentasodium (TPP): chitosan was optimized. For Antioxidant fraction loaded chitosan nanoparticles, the fraction is physically incorporated into the chitosan nanoparticles. Particle morphology was monitored by Scanning Electron Microscopy (SEM). Results: One polar fraction by Rf = 0.03 has a strong antibacterial activity that shows terpenoids characterization. Chitosan nanoparticle loaded antioxidant-antibacterial material has longer life span while compare to Cs-NPs alone. The antioxidant-antibacterial material was released relatively slowly from the CS NPs. the antibacterial trait of the fraction was increased about 8-16 times after combination with Cs NPs. Conclusions: Combination of Cs NPs with antioxidant-antibacterail fraction isolated from Lactobacillus casei increase the Cs NPs stability and antibacterial activity of the fraction was enhanced considerably, also.
https://www.nanomedicine-rj.com/article_25576_f6637bf160aff636f6c04695a5f6563c.pdf
2017-04-01
123
130
10.22034/nmrj.2017.62889.1065
chitosan nanoparticles
ionic gelation
Antioxidant-antibacterial fraction
Lactobacillus casei
Zahra
Pourramezan
z.pourramezan@gmail.com
1
Department of Microbiology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran
LEAD_AUTHOR
Rouha
Kasra Kermanshahi
rkasra@alzahra.ac.ir
2
Department of Microbiology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran
AUTHOR
Aliasghar
Katbab
z.pourramezan@alzahra.ac.ir
3
Department of Polymer Engineering and Color Technology, Amirkabir University of Technology, Tehran, Iran
AUTHOR
1.Ober CA, Gupta RB. Nanoparticle Technology for Drug Delivery. Ide@s CONCYTEG. 2011;6(72):714-26.
1
2.Jain KK. Ethical, Safety, and Regulatory Issues of Nanomedicine. The Handbook of Nanomedicine: Springer; 2008. p. 329-52.
2
3.SzymaSka E, Winnicka K. Preparation and in vitro evaluation of chitosan microgranules with clotrimazole. Acta Pol Pharm Drug Res. 2012;69(3):509-13.
3
4.Hurler J, Škalko-Basnet N. Potentials of chitosan-based delivery systems in wound therapy: Bioadhesion study. J Funct Biomater. 2012;3(1):37-48.
4
5.Venkatesan J, Bhatnagar I, Kim S-K. Chitosan-alginate biocomposite containing fucoidan for bone tissue engineering. Mar drugs. 2014;12(1):300-16.
5
6.Okamoto Y, Yano R, Miyatake K, Tomohiro I, Shigemasa Y, Minami S. Effects of chitin and chitosan on blood coagulation. Carbohydr Polym. 2003;53(3):337-42.
6
7.Hoemann C, Sun J, Legare A, McKee M, Buschmann M. Tissue engineering of cartilage using an injectable and adhesive chitosan-based cell-delivery vehicle. Osteoarthritis cartilage. 2005;13(4):318-29.
7
8.Chattopadhyay D, Inamdar M. Improvement in properties of cotton fabric through synthesized nano-chitosan application. JFTR. 2013;38(1):14-21.
8
9.Benhabiles M, Salah R, Lounici H, Drouiche N, Goosen M, Mameri N. Antibacterial activity of chitin, chitosan and its oligomers prepared from shrimp shell waste. Food hydrocolloids. 2012;29(1):48-56.
9
10.Lahmer RA, Williams AP, Townsend S, Baker S, Jones DL. Antibacterial action of chitosan-arginine against Escherichia coli O157 in chicken juice. Food Control. 2012;26(1):206-11.
10
11.Cruz-Romero M, Murphy T, Morris M, Cummins E, Kerry J. Antimicrobial activity of chitosan, organic acids and nano-sized solubilisates for potential use in smart antimicrobially-active packaging for potential food applications. Food Control. 2013;34(2):393-7.
11
12.Szymańska E, Winnicka K, Wieczorek P, Sacha PT, Tryniszewska EA. Influence of Unmodified and β-Glycerophosphate Cross-Linked Chitosan on Anti-Candida Activity of Clotrimazole in Semi-Solid Delivery Systems. Int J Mol Sci. 2014;15(10):17765-77.
12
13.Mostafa Amin D, Adel Zak E-S, Mohamed Mohamed A-H, Dina Mohamed Diaa B. Thermal stability and degradation of chitosan modified by cinnamic acid. OJPChem. 2012;2012.
13
14.Szymańska E, Winnicka K. Stability of chitosan—a challenge for pharmaceutical and biomedical applications. Mar drugs. 2015;13(4):1819-46.
14
15.Jang K-I, Lee HG. Stability of chitosan nanoparticles for L-ascorbic acid during heat treatment in aqueous solution. J Agric Food Chem. 2008;56(6):1936-41.
15
16.Xing J, Wang G, Zhang Q, Liu X, Gu Z, Zhang H, et al. Determining Antioxidant Activities of Lactobacilli Cell-Free Supernatants by Cellular Antioxidant Assay: A Comparison with Traditional Methods. PLOS ONE. 2015;10(3):e0119058.
16
17.Wegkamp A, Teusink B, De Vos W, Smid E. Development of a minimal growth medium for Lactobacillus plantarum. Lett Appl Microbiol. 2010;50(1):57-64.
17
18.Saadatzadeh A, Fazeli MR, Jamalifar H, Dinarvand R. Probiotic properties of Lyophilized cell free extract of Lactobacillus casei. Jundishapur J Nat Pharm Prod. 2013;8(3):131-7.
18
19.Jaime L, Mendiola JA, Herrero M, Soler‐Rivas C, Santoyo S, Señorans FJ, et al. Separation and characterization of antioxidants from Spirulina platensis microalga combining pressurized liquid extraction, TLC, and HPLC‐DAD. J Sep Sci. 2005;28(16):2111-9.
19
20.Arullappan S, Rajamanickam P, Thevar N, Narayanasamy D, Yee HY, Kaur P, et al. Cytotoxic effect and antioxidant activity of bioassay-guided fractions from Solanum nigrum extracts. Trop J Pharm Res. 2015;14(7):1199-205.
20
21.Jayashree D. Phytochemicals analysis and TLC finger printing Of methanolic extracts of three medicinal plants. Int Res J Pharm. 2013;4(6):123-1236.
21
22.Ibrahim HM, El-Bisi MK, Taha GM, El-Alfy EA. Chitosan nanoparticles loaded antibiotics as drug delivery biomaterial. J App Pharm Sci. 2015;5(10): 085-090.
22
23.Sailaja AK. Formulation and evaluation studies of BSA loaded chitosan nanoparticles by polymerization technique. Int J Adv Pharm. 2016;5(3):66-75.
23
24.Rivero S, García M, Pinotti A. Physical and chemical treatments on chitosan matrix to modify film properties and kinetics of biodegradation. Journal of Materials Physics and Chemistry. 2013;1(3):51-7.
24
25.Zuluaga F SDJB. Evaluation of Biocompatibility of Chitosan Films from the Mycelium of Aspergillus niger in Connective Tissue of Rattus norvegicus. J Mol Genet Med. 2015;09(03).
25
26.Balouiri M, Sadiki M, Ibnsouda SK. Methods for in vitro evaluating antimicrobial activity: A review. J Pharm Anal. 2016;6(2):71-9.
26
27.Liu L, Dong X, Zhu D, Song L, Zhang H, Leng XG. TAT-LHRH conjugated low molecular weight chitosan as a gene carrier specific for hepatocellular carcinoma cells. Int J Nanomedicine. 2014;9:2879.
27
28.Lu Y, Cheng D, Lu S, Huang F, Li G. Preparation of quaternary ammonium salt of chitosan nanoparticles and their textile properties on Antheraea pernyi silk modification. Text Res J. 2014;84(19):2115-24.
28
29.Nascimento AV, Singh A, Bousbaa H, Ferreira D, Sarmento B, Amiji MM. Mad2 checkpoint gene silencing using epidermal growth factor receptor-targeted chitosan nanoparticles in non-small cell lung cancer model. Mol Pharm. 2014;11(10):3515.
29
30.Ragelle H, Riva R, Vandermeulen G, Naeye B, Pourcelle V, Le Duff C, et al. Chitosan nanoparticles for siRNA delivery: optimizing formulation to increase stability and efficiency. J Control Release. 2014;176:54-63.
30
31.Pan Y, Li Y-j, Zhao H-y, Zheng J-m, Xu H, Wei G, et al. Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo. Int J Pharm. 2002;249(1):139-47.
31
32.Gan Q, Wang T. Chitosan nanoparticle as protein delivery carrier—systematic examination of fabrication conditions for efficient loading and release. Colloids and Surfaces B: Biointerfaces. 2007;59(1):24-34.
32
33.Mitra A, Dey B. Chitosan microspheres in novel drug delivery systems. Indian J Pharm Sci. 2011;73(4):355.
33
34.Agnihotri SA, Mallikarjuna NN, Aminabhavi TM. Recent advances on chitosan-based micro-and nanoparticles in drug delivery. J Control Release. 2004;100(1):5-28.
34
35.Esmaeilzadeh-Gharedaghi E, Faramarzi MA, Amini MA, Rouholamini Najafabadi A, Rezayat SM, Amani A. Effects of processing parameters on particle size of ultrasound prepared chitosan nanoparticles: An Artificial Neural Networks Study. Pharm Dev Technol. 2012;17(5):638-47.
35
36.Katas H, Raja MAG, Lam KL. Development of chitosan nanoparticles as a stable drug delivery system for protein/siRNA. Int J Biomate. 2013;2013.
36
37.Abou-Zeid N, Waly A, Kandile N, Rushdy A, El-Sheikh M, Ibrahim H. Preparation, characterization and antibacterial properties of cyanoethylchitosan/cellulose acetate polymer blended films. Carbohydr Polym. 2011;84(1):223-30.
37
38.Avadi M, Sadeghi A, Tahzibi A, Bayati K, Pouladzadeh M, Zohuriaan-Mehr M, et al. Diethylmethyl chitosan as an antimicrobial agent: Synthesis, characterization and antibacterial effects. Eur Polym J. 2004;40(7):1355-61.
38
ORIGINAL_ARTICLE
Fabrication and characterization of nanofibrous tricuspid valve scaffold based on polyurethane for heart valve tissue engineering
Objective(s): Tissue engineering represents a new approach to solve the current complications of the heart valve replacements by offering viable valve prosthesis with growth and remodeling capability. In this project, electrospinning and dip coating techniques were used to fabricate heart valve constructs from medical grade polyurethane (PU). Methods: First, a mold of tricuspid valve was dip coated in a PU solution, except for its valvular parts. Then, PU nanofibers were electrospun on the dip coated mold to form the valves. The morphology and diameter of nanofibers were investigated by SEM and contact angle measurements were done to evaluate the wettability of scaffolds. Thereafter, a tensile tester machine was used to assess mechanical properties of nanofibrous scaffolds. Then, the HUVEC cell line was cultured on the surface of scaffolds. Results: The SEM images showed the proper nanofibrous structure of the prepared scaffolds. Also, the obtained structure demonstrated appropriate tensile properties. Based on direct and indirect MTT, DAPI staining and SEM results, nanofibers were biocompatible and cells attached to the surface of the scaffolds, properly. Conclusions: This study demonstrated polyurethane-based nanofibrous scaffolds for engineering artificial heart valve. The presented scaffold provides temporary support for cells prior to generation of extracellular matrix (ECM).
https://www.nanomedicine-rj.com/article_25686_34a5d022af697ac93e7ad372aba4d8fb.pdf
2017-04-01
131
141
10.22034/nmrj.2017.63166.1067
Electrospinning
Nanofibers
Heart valve
Polyurethane
Saman
Firoozi
s-firoozi@razi.tums.ac.ir
1
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Mohammad Ali
Derakhshan
m.ali_derakhshan@yahoo.com
2
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Roya
Karimi
roya.karimi1983@gmail.com
3
Department of Tissue engineering, School of Advanced Technologies, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Ali
Rashti
rashti.ali68@yahoo.com
4
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Babak
Negahdari
b.negahdari@sina.tums.ac.ir
5
Department of Medical Biotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Reza
Faridi Majidi
refaridi@sina.tums.ac.ir
6
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
AUTHOR
Samaneh
Mashaghi
samaneh.mashaghi@gmail.com
7
Laboratory for Integrated Science and Engineering School of Engineering and Applied Sciences Harvard University 9 Oxford St. Cambridge, MA 02138
AUTHOR
Hossien
Ghanbari
hghanbari@tums.ac.ir
8
Department of Medical Nanotechnology, School of Advanced Technologies in Medicine, Tehran University of Medical Sciences, Tehran, Iran
LEAD_AUTHOR
1.Murray CJ, Richards MA, Newton JN, Fenton KA, Anderson HR, Atkinson C, Bennett D, Bernabé E, Blencowe H, Bourne R. UK health performance: findings of the Global Burden of Disease Study 2010. The lancet. 2013;381 (9871):997-1020.
1
2.Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, Ferguson TB, Ford E, Furie K, Gillespie C. Heart disease and stroke statistics—2010 update A report from the American Heart Association. Circulation. 2010;121 (7):e46-e215.
2
3.Nichols M, Townsend N, Scarborough P, Rayner M. Cardiovascular disease in Europe: epidemiological update. Eur Heart J. 2013;34 (39):3028-3034.
3
4.Marijon E, Celermajer DS, Tafflet M, El-Haou S, Jani DN, Ferreira B, Mocumbi A-O, Paquet C, Sidi D, Jouven X. Rheumatic heart disease screening by echocardiography the inadequacy of World Health Organization criteria for optimizing the diagnosis of subclinical disease. Circulation. 2009;120 (8):663-668.
4
5.Marijon E, Ou P, Celermajer DS, Ferreira B, Mocumbi AO, Jani D, Paquet C, Jacob S, Sidi D, Jouven X. Prevalence of rheumatic heart disease detected by echocardiographic screening. N Engl J Med. 2007;357 (5):470-476.
5
6.Lanza R, Langer R, Vacanti JP. Principles of tissue engineering: Academic press; 2011.
6
7.Rahimtoola SH. Choice of prosthetic heart valve in adults: an update. J Am Coll Cardiol. 2010;55 (22):2413-2426.
7
8.Hammermeister K, Sethi GK, Henderson WG, Grover FL, Oprian C, Rahimtoola SH. Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve: final report of the Veterans Affairs randomized trial. J Am Coll Cardiol. 2000;36 (4):1152-1158.
8
9.Ghanbari H, Viatge H, Kidane AG, Burriesci G, Tavakoli M, Seifalian AM. Polymeric heart valves: new materials, emerging hopes. Trends Biotechnol. 2009;27 (6):359-367.
9
10.Masoumi N, Annabi N, Assmann A, Larson BL, Hjortnaes J, Alemdar N, Kharaziha M, Manning KB, Mayer JE, Khademhosseini A. Tri-layered elastomeric scaffolds for engineering heart valve leaflets. Biomaterials. 2014;35 (27):7774-7785.
10
11.Amoroso NJ, D’Amore A, Hong Y, Rivera CP, Sacks MS, Wagner WR. Microstructural manipulation of electrospun scaffolds for specific bending stiffness for heart valve tissue engineering. Acta Biomater. 2012;8 (12):4268-4277.
11
12.Sohier J, Carubelli I, Sarathchandra P, Latif N, Chester AH, Yacoub MH. The potential of anisotropic matrices as substrate for heart valve engineering. Biomaterials. 2014;35 (6):1833-1844.
12
13.Eslami M, Vrana NE, Zorlutuna P, Sant S, Jung S, Masoumi N, Khavari-Nejad RA, Javadi G, Khademhosseini A. Fiber-reinforced hydrogel scaffolds for heart valve tissue engineering. J Biomater Appl. 2014:0885328214530589.
13
14.Simionescu D, Chen J, Jaeggli M, Wang B, Liao J. Form follows function: advances in trilayered structure replication for aortic heart valve tissue engineering. J Healthc Eng. 2012;3 (2):179-202.
14
15.Zimmermann W-H, Eschenhagen T. Tissue engineering of aortic heart valves. Cardiovasc Res. 2003;60 (3):460-462.
15
16.Jana S, Tefft B, Spoon D, Simari R. Scaffolds for tissue engineering of cardiac valves. Acta Biomater. 2014;10 (7):2877-2893.
16
17.Mol A, Smits AI, Bouten CV, Baaijens FP. Tissue engineering of heart valves: advances and current challenges. Expert Rev Med Devices. 2009;6 (3):259-275.
17
18.Jockenhoevel S, Zund G, Hoerstrup SP, Chalabi K, Sachweh JS, Demircan L, Messmer BJ, Turina M. Fibrin gel–advantages of a new scaffold in cardiovascular tissue engineering. Eur J Cardiothorac Surg. 2001;19 (4):424-430.
18
19.Ye Q, Zünd G, Benedikt P, Jockenhoevel S, Hoerstrup SP, Sakyama S, Hubbell JA, Turina M. Fibrin gel as a three dimensional matrix in cardiovascular tissue engineering. Eur J Cardiothorac Surg. 2000;17 (5):587-591.
19
20.Costa ML, Escaleira RC, Jazenko F, Mermelstein CS. Cell adhesion in zebrafish myogenesis: distribution of intermediate filaments, microfilaments, intracellular adhesion structures and extracellular matrix. Cell Motil Cytoskeleton. 2008;65 (10):801-815.
20
21.Guex A, Kocher F, Fortunato G, Körner E, Hegemann D, Carrel T, Tevaearai H, Giraud M. Fine-tuning of substrate architecture and surface chemistry promotes muscle tissue development. Acta Biomater. 2012;8 (4):1481-1489.
21
22.Ma Z, Kotaki M, Inai R, Ramakrishna S. Potential of nanofiber matrix as tissue-engineering scaffolds. Tissue engineering. 2005;11 (1-2):101-109.
22
23.Derakhshan MA, Pourmand G, Ai J, Ghanbari H, Dinarvand R, Naji M, Faridi-Majidi R. Electrospun PLLA nanofiber scaffolds for bladder smooth muscle reconstruction. Int Urol Nephrol. 2016;48 (7):1097-1104.
23
24.Gheibi A, Khoshnevisan K, Ketabchi N, Derakhshan MA, Babadi AA. Application of Electrospun Nanofibrous PHBV Scaffold in Neural Graft and Regeneration: A Mini-Review. Nanomed Res J. 2016;1 (2):107-111.
24
25.Shirian S, Ebrahimi-Barough S, Saberi H, Norouzi-Javidan A, Mousavi SMM, Derakhshan MA, Arjmand B, Ai J. Comparison of Capability of Human Bone Marrow Mesenchymal Stem Cells and Endometrial Stem Cells to Differentiate into Motor Neurons on Electrospun Poly(ε-caprolactone) Scaffold. Mol Neurobiol. 2015:1-10.
25
26.Sharifi-Aghdam M, Faridi-Majidi R, Derakhshan MA, Chegeni A, Azami M. Preparation of collagen/polyurethane/knitted silk as a composite scaffold for tendon tissue engineering. Proc Inst Mech Eng H. 2017:0954411917697751.
26
27.Rockwood DN, Woodhouse KA, Fromstein JD, Chase DB, Rabolt JF. Characterization of biodegradable polyurethane microfibers for tissue engineering. J Biomater Sci Polym Ed. 2007;18 (6):743-758.
27
28.Theron J, Knoetze J, Sanderson R, Hunter R, Mequanint K, Franz T, Zilla P, Bezuidenhout D. Modification, crosslinking and reactive electrospinning of a thermoplastic medical polyurethane for vascular graft applications. Acta Biomater. 2010;6 (7):2434-2447.
28
29.Davoudi P, Assadpour S, Derakhshan MA, Ai J, Solouk A, Ghanbari H. Biomimetic modification of polyurethane-based nanofibrous vascular grafts: A promising approach towards stable endothelial lining. Materials Science and Engineering: C. 2017.
29
30.Carlberg B, Axell MZ, Nannmark U, Liu J, Kuhn HG. Electrospun polyurethane scaffolds for proliferation and neuronal differentiation of human embryonic stem cells. Biomed Mater. 2009;4 (4):045004.
30
31.Mohamadi F, Ebrahimi‐Barough S, Reza Nourani M, Ali Derakhshan M, Goodarzi V, Sadegh Nazockdast M, Farokhi M, Tajerian R, Faridi Majidi R, Ai J. Electrospun nerve guide scaffold of poly (ε‐caprolactone)/collagen/nanobioglass: an in vitro study in peripheral nerve tissue engineering. J Biomed Mater Res A. 2017;105 (7):1960-1972.
31
32.Stankus JJ, Guan J, Wagner WR. Fabrication of biodegradable elastomeric scaffolds with sub‐micron morphologies. J Biomed Mater Res A. 2004;70 (4):603-614.
32
33.Soletti L, Hong Y, Guan J, Stankus JJ, El-Kurdi MS, Wagner WR, Vorp DA. A bilayered elastomeric scaffold for tissue engineering of small diameter vascular grafts. Acta Biomater. 2010;6 (1):110-122.
33
34.Chen R, Morsi Y, Patel S, Ke Q-f, Mo X-m. A novel approach via combination of electrospinning and FDM for tri-leaflet heart valve scaffold fabrication. Frontiers of Materials Science in China. 2009;3 (4):359-366.
34
35.Thierfelder N, Koenig F, Bombien R, Fano C, Reichart B, Wintermantel E, Schmitz C, Akra B. In vitro comparison of novel polyurethane aortic valves and homografts after seeding and conditioning. ASAIO J. 2013;59 (3):309-316.
35
36.Hobson CM, Amoroso NJ, Amini R, Ungchusri E, Hong Y, D'Amore A, Sacks MS, Wagner WR. Fabrication of elastomeric scaffolds with curvilinear fibrous structures for heart valve leaflet engineering. J Biomed Mater Res A. 2015.
36
37.Firoozi S, Amani A, Derakhshan MA, Ghanbari H. Artificial Neural Networks Modeling of Electrospun Polyurethane Nanofibers from Chloroform/Methanol Solution. Journal of Nano Research. Vol 41: Trans Tech Publ; 2016:18-30.
37
38.Yao C, Hedrick M, Pareek G, Renzulli J, Haleblian G, Webster TJ. Nanostructured polyurethane-poly-lactic-co-glycolic acid scaffolds increase bladder tissue regeneration: an in vivo study. Int J Nanomedicine. 2013;8:3285.
38
39.Thapa A, Miller DC, Webster TJ, Haberstroh KM. Nano-structured polymers enhance bladder smooth muscle cell function. Biomaterials. 2003;24 (17):2915-2926.
39
40.Tsang M, Chun YW, Im YM, Khang D, Webster TJ. Effects of increasing carbon nanofiber density in polyurethane composites for inhibiting bladder cancer cell functions. Tissue Eng Part A. 2011;17 (13-14):1879-1889.
40
41.Yeganegi M, Kandel RA, Santerre JP. Characterization of a biodegradable electrospun polyurethane nanofiber scaffold: mechanical properties and cytotoxicity. Acta biomater. 2010;6 (10):3847-3855.
41
42.Dasdemir M, Topalbekiroglu M, Demir A. Electrospinning of thermoplastic polyurethane microfibers and nanofibers from polymer solution and melt. J Appl Polym Sci. 2013;127 (3):1901-1908.
42
43.He W, Ma Z, Yong T, Teo WE, Ramakrishna S. Fabrication of collagen-coated biodegradable polymer nanofiber mesh and its potential for endothelial cells growth. Biomaterials. 2005;26 (36):7606-7615.
43
44.Mo X, Xu C, Kotaki Mea, Ramakrishna S. Electrospun P (LLA-CL) nanofiber: a biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation. Biomaterials. 2004;25 (10):1883-1890.
44
45.Yuan J, Zhu J, Zhu C, Shen J, Lin S. Platelet adhesion on a polyurethane surface grafted with a zwitterionic monomer of sulfobetaine via a Jeffamine spacer. Polym Int. 2004;53 (11):1722-1728.
45
46.Sanchis M, Calvo O, Fenollar O, Garcia D, Balart R. Surface modification of a polyurethane film by low pressure glow discharge oxygen plasma treatment. J Appl Polym Sci. 2007;105 (3):1077-1085.
46
47.Zandén C, Voinova M, Gold J, Mörsdorf D, Bernhardt I, Liu J. Surface characterisation of oxygen plasma treated electrospun polyurethane fibres and their interaction with red blood cells. Eur Polym J. 2012;48 (3):472-482.
47
48.Cassie A, Baxter S. Wettability of porous surfaces. Transactions of the Faraday Society. 1944;40:546-551.
48
49.Mendelson K, Schoen FJ. Heart valve tissue engineering: concepts, approaches, progress, and challenges. Ann Biomed Eng. 2006;34 (12):1799-1819.
49
50.Weinberg EJ, Kaazempur-Mofrad MR. On the constitutive models for heart valve leaflet mechanics. Cardiovascular Engineering. 2005;5 (1):37-43.
50
51.Grashow JS, Yoganathan AP, Sacks MS. Biaixal stress–stretch behavior of the mitral valve anterior leaflet at physiologic strain rates. Ann Biomed Eng. 2006;34 (2):315-325.
51
52.Pedicini A, Farris RJ. Mechanical behavior of electrospun polyurethane. Polymer. 2003;44 (22):6857-6862.
52
53.Hasan A, Ragaert K, Swieszkowski W, Selimović Š, Paul A, Camci-Unal G, Mofrad MR, Khademhosseini A. Biomechanical properties of native and tissue engineered heart valve constructs. J Biomech. 2014;47 (9):1949-1963.
53