ORIGINAL_ARTICLE
Selenium nanoparticles role in organ systems functionality and disorder
Extensive research on the nutritional and medical application of selenium nanoparticles (SeNPs) was performed in past decades. Besides nutritional values, new characteristics such as antibacterial and anticancer properties depict a bright future for high Selenium (Se) consumption in the coming years. Se is essential for the proper functioning of most of the major body organ systems meanwhile it could be highly toxic and even cancerous. The current knowledge of Se interaction with major organ systems functionality such as the central nervous system isn’t well studied and many physiological aspects aren’t clear to the science community. Meanwhile, various results were published on increasing organ system functionality through administrated SeNPs. So with the rapid entrance of SeNPs in the medical and nutritional industry, it may cause unintended complications. The intent of this review is to investigate current knowledge of SeNPs interaction with major body organ systems functionality. Investigated pharmacokinetic parameters of SeNPs was also reviewed.
https://www.nanomedicine-rj.com/article_32922_aa339b00b827b9f1ef69d52ca6cd9716.pdf
2018-09-01
117
124
10.22034/nmrj.2018.03.001
Antioxidant
Nanopharmacokinetic
Nanotoxicity
Organ Function
Selenium Nanoparticles
Seyed Mohaamad
Amini
mohammadamini86@gmail.com
1
Radiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran
LEAD_AUTHOR
Vahid
Pirhajati Mahabadi
vpirhajati.1@gmail.com
2
Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran
AUTHOR
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89
ORIGINAL_ARTICLE
Antimicrobial properties and permeability of Poly lactic Acid nanocomposite films containing Zinc Oxide
Objective(s): Since microbial contamination can reduce the shelf life of the foodstuff and there is a potential for the growth of some pathogen microorganisms, films containing antimicrobial agents were produced, which are also biodegradable. In this study, the effect of 1, 3 and 5% nano-zinc oxide on antimicrobial properties and permeability of poly lactic acid film was investigated.
Material and methods: the sample was contaminated with standard strains of gram-negative (Escherichia coli –code of 1399 (ATCC 25992)) and bacteria gram-positive (Staphylococcus aureus–code of 1431 (ATCC 25923)) provided. Diameters of inhibition zones were measured after 24 h incubation of plates at 37 °C, by using Digital Caliper. Also, the permeability to water vapor according to ASTM E96 and oxygen standards according to ASTM D3985 standard was investigated from film surface.
Results: The study of antimicrobial properties of films on Escherichia coli and Staphylococcus aureus showed that all three percent of “ZnO” in this study had inhibitory effects and increased the percentage of nano-zinc oxide significantly (P <0.05) increased the inhibitory effects.In this test, the diameter of the control film inhibition zone was zero, which indicates that pure poly lactic acid films do not have antimicrobial activity (P > 0.05). In the study of Water Vapor Permeability (WVP), bio-composite films with 1% and 3% nano-zinc oxide showed a 19% water vapor Permeability enhancement compared to the pure poly-lactic acid. Moreover, adding 3% nano-zinc oxide had an impact on the reduction of permeability to oxygen.
Conclusion: Poly lactic acid films containing nano-zinc oxide have a high potential for antimicrobial food packaging applications to enhance the safety of food products.
https://www.nanomedicine-rj.com/article_32923_01b13dc62698041458df796c56260c9c.pdf
2018-09-01
125
132
10.22034/nmrj.2018.03.002
Antimicrobial
Nano-Zinc Oxide
Permeability
Poly-Lactic Acid Nanocomposite Films
Mahya
Shafiee Nasab
1
Agricultural Engineering-Food Sciences and Industries, Islamic Azad University, Tehran North Branch, Tehran, Iran
AUTHOR
Mahsa
Tabari
ma.tabari@gmail.com
2
Agricultural Engineering-Food Sciences and Industries, Islamic Azad University, Tehran North Branch, Tehran, Iran
LEAD_AUTHOR
1. Monad, A. Novel silicon dioxide -based nanocomposites as an antimicrobial in poly (lactic acid) nanocomposites films. Nanomedicine Research Journal, 2018. J 3(2):65-70.
1
2. Tabari M. Investigation of Carboxymethyl Cellulose (CMC) on Mechanical Properties of Cold Water Fish Gelatin Biodegradable Edible Films. Foods. 2017;6(6):41.
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3. Garlotta, D., A literature review of poly (lactic acid). Journal of Polymers and the Environment, 2001. 9(2): p. 63-84.
3
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6
7. Neethirajan S, Jayas DS. Nanotechnology for the Food and Bioprocessing Industries. Food and Bioprocess Technology. 2010;4(1):39-47.
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8. Tabari, M. Characterization of a new biodegradable edible film based on Sago Starch loaded with Carboxymethyl Cellulose nanoparticles. Nanomedicine Research Journal, 2018. 3(1): 25-30.
8
9. Shafiee Nasab, M., Tabari, M., Azizi, M. H. Morphological and mechanical properties of Poly (lactic Acid) / zinc oxide nanocomposite films. Nanomedicine Research Journal, 2018. 3(2):96-101.
9
10. Tabari K, Tabari M. Characterization of a biodegrading bacterium, Bacillus subtilis, isolated from oil-contaminated soil. International Journal of Environmental Science and Technology. 2017;14(12):2583-90.
10
11. Silvestre C, Cimmino S, Pezzuto M, Marra A, Ambrogi V, Dexpert-Ghys J, et al. Preparation and characterization of isotactic polypropylene/zinc oxide microcomposites with antibacterial activity. Polymer Journal. 2013;45(9):938-45.
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12. Marra, A., Biodegradable PLA composites with different fillers for food packaging application. 2015.
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19. Sondi I, Salopek-Sondi B. Silver nanoparticles as antimicrobial agent: a case study on E. coli as a model for Gram-negative bacteria. Journal of Colloid and Interface Science. 2004;275(1):177-82.
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20. Raghupathi KR, Koodali RT, Manna AC. Size-Dependent Bacterial Growth Inhibition and Mechanism of Antibacterial Activity of Zinc Oxide Nanoparticles. Langmuir. 2011;27(7):4020-8.
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21. Alzoreky NS, Nakahara K. Antibacterial activity of extracts from some edible plants commonly consumed in Asia. International Journal of Food Microbiology. 2003;80(3):223-30.
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22. Tabari M, Tabari K, Karimzadegan H, Mohammadi M. Study on Bacillus Isolated from Intestine of Persian Sturgeon (Acipenser persicus) Comparing with Commercial Probiotics. International Letters of Natural Sciences. 2016;60:59-65.
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25. Li XH, Xing YG, Li WL, Jiang YH, Ding YL. Antibacterial and Physical Properties of Poly(vinyl chloride)-based Film Coated with ZnO Nanoparticles. Food Science and Technology International. 2010;16(3):225-32.
25
26. Marra A, Silvestre C, Duraccio D, Cimmino S. Polylactic acid/zinc oxide biocomposite films for food packaging application. International Journal of Biological Macromolecules. 2016;88:254-62.
26
ORIGINAL_ARTICLE
Silk suture reinforced with Cefixime nanoparticles using polymer hydrogel (CFX@PVA); Preparation, Bacterial resistance and Mechanical properties
Objective(s): The objective of the current study was to prevent surgical site infection (SSI) by creating a new antibacterial silk suture.
Methods: Cefixime trihydrate (CFX) was prepared as nanoparticles via mixing with polyvinyl alcohol (PVA) hydrogel by covalent cross-linkage. The mixture was stirred vigorously to obtain a homogenous gel. Under this condition the polymer chains separate CFX as nanoparticles and trap them (CFX@PVA). The enrichment of silk suture was performed by immersing it in the CFX@PVA solution. The trapped CFX nanoparticles in PVA hydrogel on the surface of sutures were confirmed by SEM. The effect of CFX@PVA silk sutures on tensile strength was analyzed, using a Santammachine controller. The antibacterial activity of the reinforced silk suture was tested on E. coli (ATCC25922) and S. aureus (ATCC25924).
Results: All antibacterial studies clearly showed that the use of novel CFX@PVA silk sutures could represent clinical advantages, in terms of prevention of resistant bacteria, such as Staphylococcus aureus (S. aureus), the same as the sensitive bacteria, for 15 days. The maximum elongation of composite before rupture, modulus and extension, showed statistically significant difference between reinforced silk sutures and untreated silk suture. No statistically significant difference was found between the Failure load, Stress, Bending and Energy.
Conclusions: Our data indicate that CFX@ Silk sutures are capable of reducing the risk of SSIs, and has a good mechanical strength to keep the wound sides closed, during early healing recovery.
https://www.nanomedicine-rj.com/article_32921_b17704fa8fa6a5123aa9ce5f20191858.pdf
2018-09-01
133
139
10.22034/nmrj.2018.03.003
Silk suture
Cefixime trihydrate
Polyvinyl alcohol
Nanoparticle
Antibacterial activity
Mechanical properties
Ali
Alirezaie Alavijeh
alirezaie108@gmail.com
1
Department of Pathology, Medical Faculty, AJA University of Medical Sciences, Tehran, Iran
AUTHOR
Masoomeh
Dadpey
md.science501@gmail.com
2
Department of Pathology, Medical Faculty, AJA University of Medical Sciences, Tehran, Iran
LEAD_AUTHOR
Mohammad
Barati
barati.m@kashanu.ac.ir
3
Department of Applied Chemistry, Faculty of Chemistry, University of Kashan, Kashan, Iran
AUTHOR
Afsaneh
Molamirzaie
af.molamirzari@gmail.com
4
Department of Biotechnology, Islamic Azad University, Falavarjan Branch, Falavarjan, Iran
AUTHOR
1. Mingmalairak, C. Antimicrobial sutures: new strategy in surgical site infections. Science against Microbial Pathogens: Communicating Current Research and Technological Advances: Formatex Research Center. 2011:313-323.
1
2. Seal LA, Paul-Cheadle D. A systems approach to preoperative surgical patient skin preparation. American Journal of Infection Control. 2004;32(2):57-62.
2
3. Ming X, Rothenburger S, Nichols MM. In Vivo and In Vitro Antibacterial Efficacy of PDS Plus (Polidioxanone with Triclosan) Suture. Surgical Infections. 2008;9(4):451-7.
3
4. Gómez-Alonso A, García-Criado FJ, Parreño-Manchado FC, García-Sánchez JE, García-Sánchez E, Parreño-Manchado A, et al. Study of the efficacy of Coated VICRYL Plus® Antibacterial suture (coated Polyglactin 910 suture with Triclosan) in two animal models of general surgery. Journal of Infection. 2007;54(1):82-8.
4
5. Swanson NA, Tromovitch TA. Suture Materials, 1980s: Properties, Uses, and Abuses. International Journal of Dermatology. 1982;21(7):373-8.
5
6. Altman GH, Diaz F, Jakuba C, Calabro T, Horan RL, Chen J, et al. Silk-based biomaterials. Biomaterials. 2003;24(3):401-16.
6
7. Leaper D, McBain AJ, Kramer A, Assadian O, Sanchez JLA, Lumio J, et al. Healthcare associated infection: novel strategies and antimicrobial implants to prevent surgical site infection. The Annals of The Royal College of Surgeons of England. 2010;92(6):453-8.
7
8. Ford HR, Jones P, Gaines B, Reblock K, Simpkins DL. Intraoperative Handling and Wound Healing: Controlled Clinical Trial Comparing Coated VICRYL® Plus Antibacterial Suture (Coated Polyglactin 910 Suture with Triclosan) with Coated VICRYL® Suture (Coated Polyglactin 910 Suture). Surgical Infections. 2005;6(3):313-21.
8
9. Rozzelle CJ, Leonardo J, Li V. Antimicrobial suture wound closure for cerebrospinal fluid shunt surgery: a prospective, double-blinded, randomized controlled trial. Journal of Neurosurgery: Pediatrics. 2008;2(2):111-7.
9
10. Fleck T, Moidl R, Blacky A, Fleck M, Wolner E, Grabenwoger M, et al. Triclosan-Coated Sutures for the Reduction of Sternal Wound Infections: Economic Considerations. The Annals of Thoracic Surgery. 2007;84(1):232-6.
10
11. Justinger C, Moussavian MR, Schlueter C, Kopp B, Kollmar O, Schilling MK. Antibiotic coating of abdominal closure sutures and wound infection. Surgery. 2009;145(3):330-4.
11
12. Mingmalairak, C, Ungbhakorn, P,Paocharoen, V. Efficacy of antimicrobial coating suture coated polyglactin 910 with tricosan (Vicryl plus) compared with polyglactin 910 (Vicryl) in reduced surgical site infection of appendicitis, double blind randomized control trial, preliminary safety report. Medical journal of the Medical Association of Thailand. 2009;92(6):770.
12
13. Hooper, D. Mechanisms of quinolone action and bacterial killing. Quinolone antimicrobial agents. 1993:53-75.
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14. Jensen BEB, Hosta-Rigau L, Spycher PR, Reimhult E, Städler B, Zelikin AN. Lipogels: surface-adherent composite hydrogels assembled from poly(vinyl alcohol) and liposomes. Nanoscale. 2013;5(15):6758.
14
15. Jensen BEB, Smith AAA, Fejerskov B, Postma A, Senn P, Reimhult E, et al. Poly(vinyl alcohol) Physical Hydrogels: Noncryogenic Stabilization Allows Nano- and Microscale Materials Design. Langmuir. 2011;27(16):10216-23.
15
16. Jensen BEB, Alves M-H, Fejerskov B, Städler B, Zelikin AN. Surface adhered poly(vinyl alcohol) physical hydrogels as tools for rational design of intelligent biointerfaces. Soft Matter. 2012;8(17):4625.
16
17. Hoare TR, Kohane DS. Hydrogels in drug delivery: Progress and challenges. Polymer. 2008;49(8):1993-2007.
17
18. Hosta-Rigau L, Jensen BEB, Fjeldsø KS, Postma A, Li G, Goldie KN, et al. Surface-Adhered Composite Poly(Vinyl Alcohol) Physical Hydrogels: Polymersome-Aided Delivery of Therapeutic Small Molecules. Advanced Healthcare Materials. 2012;1(6):791-5.
18
19. Hoffman AS. Hydrogels for biomedical applications. Advanced Drug Delivery Reviews. 2012;64:18-23.
19
20. Řı́hová B. Immunocompatibility and biocompatibility of cell delivery systems. Advanced Drug Delivery Reviews. 2000;42(1-2):65-80.
20
21. Afghan, N. Mechanical Properties of Poly (vinyl alcohol) Based Blends and
21
22. Millon, LE. Isotropic and anisotropic polyvinyl alcohol based hydrogels for biomedical applications. ProQuest; 2008.
22
23. Park H, Park K. Hydrogels in Bioapplications. ACS Symposium Series: American Chemical Society; 1996. p. 2-10.
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24. Omidian H, Park K. Introduction to Hydrogels. Biomedical Applications of Hydrogels Handbook: Springer New York; 2010. p. 1-16.
24
25. Omidian H, Park K. Hydrogels. Fundamentals and Applications of Controlled Release Drug Delivery: Springer US; 2011. p. 75-105.
25
26. Gander B, Beltrami V, Gurny R, Doelker E. Effects of the method of drug incorporation and the size of the monolith on drug release from cross-linked polymers. International Journal of Pharmaceutics. 1990;58(1):63-71.
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27. Ottenbrite, R, Park, K,Okano, T. Biomedical applications of hydrogels handbook, p 204. 2010.
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28. Lozinsky, VI, Plieva, FM, Galaev, IY,Mattiasson, B. The potential of polymeric cryogels in bioseparation. Bioseparation. 2001;10(4-5):163-188.
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29. Okay, O. Polymeric Cryogels: Macroporous gels with remarkable properties. Springer; 2014.
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30. Lozinsky VI. Cryotropic gelation of poly(vinyl alcohol) solutions. Russian Chemical Reviews. 1998;67(7):573-86.
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31. Chong S-F, Smith AAA, Zelikin AN. Microstructured, Functional PVA Hydrogels through Bioconjugation with Oligopeptides under Physiological Conditions. Small. 2012;9(6):942-50.
31
32. Fejerskov B, Smith AAA, Jensen BEB, Hussmann T, Zelikin AN. Bioresorbable Surface-Adhered Enzymatic Microreactors Based on Physical Hydrogels of Poly(vinyl alcohol). Langmuir. 2012;29(1):344-54.
32
33. Hassan CM, Peppas NA. Structure and Applications of Poly(vinyl alcohol) Hydrogels Produced by Conventional Crosslinking or by Freezing/Thawing Methods. Biopolymers · PVA Hydrogels, Anionic Polymerisation Nanocomposites: Springer Berlin Heidelberg. p. 37-65.
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34. Daraio C, Jin S. Synthesis and Patterning Methods for Nanostructures Useful for Biological Applications. Nanotechnology for Biology and Medicine: Springer New York; 2011. p. 27-44.
34
35. Tavasoli A, Kiai RM, Karimi A. Effects of particle size on the catalytic performance of MWCNTs supported alkalized MoS2catalysts promoted by Ni and Co in higher alcohols synthesis. The Canadian Journal of Chemical Engineering. 2016;94(8):1495-503.
35
36. Desai P, Pore Y. Physicochemical characterization of spray dried cefixime polymeric nanoparticles using factorial design approach. Journal of Applied Pharmaceutical Science. 2016:124-32.
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37. Bhosale RR, Shende RV, Puszynski JA. Thermochemical water-splitting for H2 generation using sol-gel derived Mn-ferrite in a packed bed reactor. International Journal of Hydrogen Energy. 2012;37(3):2924-34.
37
38. Pethile S, Chen X-J, Hou D-d, Wang L. Effect of changing coating process parameters in the preparation of antimicrobial-coated silk sutures: An in vitro study. Fibers and Polymers. 2014;15(8):1589-95.
38
39. Brogden RN, Campoli-Richards DM. Cefixime. Drugs. 1989;38(4):524-50.
39
40. Janiga PK, Elayarajah B, Rajendran R, Rammohan R, Venkatrajah B, Asa S. Drug-eluting silk sutures to retard post-operative surgical site infections. Journal of Industrial Textiles. 2011;42(2):176-90.
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41. Viju S, Thilagavathi G. Fabrication and characterization of silk braided sutures. Fibers and Polymers. 2012;13(6):782-9.
41
42. Sumpio, B,Widmann, M. Enhanced production of endothelium-derived contracting factor by endothelial cells subjected to pulsatile stretch. Surgery. 1990;108(2):277-281; discussion 281-272.
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43. Morin, G, Burgess, LP, Rand, M, Graeber, GM,Voussoughi, J. Wound healing: relationship of wound closing tension to tensile strength in rats. The Laryngoscope. 1989;99(8):783-788.
43
44. Palomba D, Vazquez GE, Díaz MF. Prediction of elongation at break for linear polymers. Chemometrics and Intelligent Laboratory Systems. 2014;139:121-31.
44
ORIGINAL_ARTICLE
PLA-SiO2 nanocomposite films: morphological and mechanical properties and specific end-use characteristics
Objective(s): Application of eco-friendly materials like poly lactic acid (PLA) is increasing, to reduce environmental pollutions. In this research, the effect of silicon dioxide 1%, 3% and 5% nanoparticles on morphological, mechanical and chemicals interaction (FTIR) of PLA film was studied.
Materials and Methods: Scanning electron microscope (SEM) was used, to consider morphological structure of nanocomposites. Mechanical characteristics of films, measurement of tensile strength, elongation at break point and Yong modulus also were considered by using tensile device and ASTM D 882. The FT-IR spectrum of films with PERKIN ELMER 1650, FT-IR spectrophotometer was recorded.
Results: Morphological evaluation of PLA composite strings shows desirable and steady distribution of nanoparticles for the sample with 1 percent weight of Silica volume and by increasing Silica contents from 1 to 5 percent, nanoparticles start to form mass. Comparison of average of tensile resistance, elongation at break point and Young modulus in pure PLA film with PLA film including 1% SiO2 shows insignificance of average of these groups (P>0.05). In the consideration, FTIR shows proper distribution of nano-SiO2 dioxide in film composites and connection is created and doesn’t have difference with pure PLA.
Conclusion: Performed considerations show that PLA films containing SiO2 have proper potential for application in packaging mechanically.
https://www.nanomedicine-rj.com/article_32924_bb87623a2a1bb07fc2a70ddc9a89ef3a.pdf
2018-09-01
140
145
10.22034/nmrj.2018.03.004
Morphological and Mechanical Properties
Poly Lactic Acid Nanocomposite Films
Silicon Dioxide Nanoparticle
Mohadeseh
Famil Zirak
1
Department of Agricultural Engineering-Food Sciences and Industries, Islamic Azad University, Tehran North Branch, Iran
AUTHOR
Mahsa
Tabari
ma.tabari@gmail.com
2
Department of Food Sciences and Industries, Faculty of Agriculture, Islamic Azad University, Tehran North Branch, Tehran, Iran
LEAD_AUTHOR
1. Shafiee Nasab, M., Tabari, M., Azizi, M. H. Morphological and mechanical properties of Poly (lactic Acid) / zinc oxide nanocomposite films. Nanomed Res Journal. 3(2):96-101, Spring 2018
1
2. Harada M, Ohya T, Iida K, Hayashi H, Hirano K, Fukuda H. Increased impact strength of biodegradable poly(lactic acid)/poly(butylene succinate) blend composites by using isocyanate as a reactive processing agent. Journal of Applied Polymer Science. 2007;106(3):1813-20.
2
3. Monad, Alireza, Novel silicon dioxide -based nanocomposites as an antimicrobial in poly (lactic acid) nanocomposites films. Nanomed Res Journal. 3(2):65-70, Spring 2018
3
4. Wu G, Liu S, Jia H, Dai J. Preparation and properties of heat resistant polylactic acid (PLA)/Nano-SiO2 composite filament. Journal of Wuhan University of Technology-Mater Sci Ed. 2016;31(1):164-71.
4
5. Tabari M. Investigation of Carboxymethyl Cellulose (CMC) on Mechanical Properties of Cold Water Fish Gelatin Biodegradable Edible Films. Foods. 2017;6(6):41.
5
6. Ahmed J, Varshney SK. Polylactides—Chemistry, Properties and Green Packaging Technology: A Review. International Journal of Food Properties. 2011;14(1):37-58.
6
7. Tabari M. Characterization of a new biodegradable edible film based on Sago Starch loaded with Carboxymethyl Cellulose nanoparticles. Nanomedicine Research Journal, 2018. 3(1): 25-30, Winter 2018.
7
8. Aydinli M, Tutas M. Water Sorption and Water Vapour Permeability Properties of Polysaccharide (Locust Bean Gum) Based Edible Films. LWT - Food Science and Technology. 2000;33(1):63-7.
8
9. Tabari K, Tabari M. Characterization of a biodegrading bacterium, Bacillus subtilis, isolated from oil-contaminated soil. International Journal of Environmental Science and Technology. 2017;14(12):2583-90.
9
10. Wu G, Liu S, Jia H, Dai J. Preparation and properties of heat resistant polylactic acid (PLA)/Nano-SiO2 composite filament. Journal of Wuhan University of Technology-Mater Sci Ed. 2016;31(1):164-71.
10
ORIGINAL_ARTICLE
Effects of silver nanoparticles on the functional tests of liver and its histological changes in adult male rats
Objective(s): Silver nanoparticles show anti-fungal properties, and is widely used in medicine. In this research, the impacts of silver nanoparticles on the hepatic functional tests and changes in liver tissues in adult male rats were investigated.
Methods: In this experimental study, 28 adult male Wistar rats, each weighing approximately 180-220 g were divided into 4 groups of 7: the control group, and the experimental groups 1 and 2 received silver nanoparticles that were synthesized at 75 seconds interval with doses of 25 and 100 mg/kg intraperitoneally for 14 days, respectively. Experimental group 3 received silver nanoparticles that were synthesized at 300 seconds interval with a dose of 25 mg/kg intraperitoneally for 14 days. At the end of experiment period, blood samples were obtained from their hearts, and serum levels of hepatic enzymes (AST, ALT, ALP), albumen and total protein were measured. In addition, possible histological changes in liver was studied after hematoxylin-eosin staining. The results were statistically analyzed using ANOVA and Duncan test.
Results: The findings reported that the mean serum levels of aspartate aminotransferase (AST), total Protein and albumin in the experimental groups 1 and 3 increased significantly relative to the control group. Similarly, the mean serum levels of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the experimental group 3 increased significantly relative to the control group (P < 0.05). Also, necrosis of the liver tissue was observed in the recipients of silver nanoparticles.
Conclusions: The use of silver nanoparticles can boost the serum levels of hepatic enzymes and Increase liver tissue necrosis as well.
https://www.nanomedicine-rj.com/article_32926_1024e0dcbb44a2e8944dc49bf3ed02be.pdf
2018-09-01
146
153
10.22034/nmrj.2018.03.005
Albumen
Hepatic Enzyme
Rat
Silver nanoparticles
Total Protein
Zohreh
Parang
zohreh.parang@gmail.com
1
Department of Physics, Shiraz Branch, Islamic Azad University, Shiraz, Iran
LEAD_AUTHOR
Davood
Moghadamnia
2
Young Researchers and Elite Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran
AUTHOR
1. Hussain SM, Schlager JJ. Safety Evaluation of Silver Nanoparticles: Inhalation Model for Chronic Exposure. Toxicological Sciences. 2009;108(2):223-4.
1
2. Bartlomiejczyk T, Lankoff A, Kruszewski M, Szumiel I. Silver nanoparticles – allies or adversaries?. Ann Agric Environ Med. 2013;20(1):48–54.
2
3. Xu L, Li X, Takemura T, Hanagata N, Wu G, Chou L. Genotoxicity and molecular response of silver nanoparticle (NP)-based hydrogel. Journal of Nanobiotechnology. 2012;10(1):16.
3
4. Suliman Y AO, Ali D, Alarifi S, Harrath AH, Mansour L, Alwasel SH. Evaluation of cytotoxic, oxidative stress, proinflammatory and genotoxic effect of silver nanoparticles in human lung epithelial cells. Environmental Toxicology. 2013;30(2):149-60.
4
5. Hussain SM, Hess KL, Gearhart JM, Geiss KT, Schlager JJ. In vitro toxicity of nanoparticles in BRL 3A rat liver cells. Toxicology in Vitro. 2005;19(7):975-83.
5
6. Mohammadi A, Vafaei SA, Nabi Moradi M, Ahmadi M, Pourjafar M, Abbasi Oshaghi E. Combination of Ezetimibe and Garlic Reduces Serum Lipids and Intestinal Niemann-Pick C1-like 1 Expression More Effectively in Hypercholesterolemic Mice. Avicenna Journal of Medical Biochemistry. 2015;3(1).
6
7. Eckle V-S, Buchmann A, Bursch W, Schulte-Hermann R, Schwarz M. Immunohistochemical Detection of Activated Caspases in Apoptotic Hepatocytes in Rat Liver. Toxicologic Pathology. 2004;32(1):9-15.
7
8. Bantel H. Detection of elevated caspase activation and early apoptosis in liver diseases. European Journal of Cell Biology. 2001;80(3):230-9.
8
9. Ansar S, Abudawood M, Hamed SS, Aleem MM. Sodium Selenite Protects Against Silver Nanoparticle-Induced Testicular Toxicity and Inflammation. Biological Trace Element Research. 2016;175(1):161-8.
9
10. Sleiman HK, Romano RM, Oliveira CAd, Romano MA. Effects of Prepubertal Exposure to Silver Nanoparticles on Reproductive Parameters in Adult Male Wistar Rats. Journal of Toxicology and Environmental Health, Part A. 2013;76(17):1023-32.
10
11. Zhang R, Lin Z, Lui VCH, Wong KKY, Tam PKH, Lee P, et al. Silver nanoparticle treatment ameliorates biliary atresia syndrome in rhesus rotavirus inoculated mice. Nanomedicine: Nanotechnology, Biology and Medicine. 2017;13(3):1041-50.
11
12. Munger MA, Radwanski P, Hadlock GC, Stoddard G, Shaaban A, Falconer J, et al. In vivo human time-exposure study of orally dosed commercial silver nanoparticles. Nanomedicine: Nanotechnology, Biology and Medicine. 2014;10(1):1-9.
12
13. ÇİFtÇİ H, TÜRk M, Tamer U, Karahan S, Menemen Y. Silver nanoparticles: cytotoxic, apoptotic, and necrotic effects on MCF-7 cells. TURKISH JOURNAL OF BIOLOGY. 2013;37:573-81.
13
14. Barros C, Fulaz S, Stanisic D, Tasic L. Biogenic Nanosilver against Multidrug-Resistant Bacteria (MDRB). Antibiotics. 2018;7(3):69.
14
15. Wang E, Huang Y, Du Q, Sun Y. Silver nanoparticle induced toxicity to human sperm by increasing ROS(reactive oxygen species) production and DNA damage. Environmental Toxicology and Pharmacology. 2017;52:193-9.
15
16. Gurunathan S, Zhang X-F, Park JH, Choi Y-J, Kang M-H, Kim J-H. Silver nanoparticles cause complications in pregnant mice. International Journal of Nanomedicine. 2015:7057.
16
17. Han JW, Jeong J-K, Gurunathan S, Choi Y-J, Das J, Kwon D-N, et al. Male- and female-derived somatic and germ cell-specific toxicity of silver nanoparticles in mouse. Nanotoxicology. 2015;10(3):361-73.
17
18. Fehaid A, Taniguchi A. Silver nanoparticles reduce the apoptosis induced by tumor necrosis factor-α. Science and Technology of Advanced Materials. 2018;19(1):526-34.
18
19. Yin B, Ma H, Wang S, Chen S. Electrochemical Synthesis of Silver Nanoparticles under Protection of Poly(N-vinylpyrrolidone). The Journal of Physical Chemistry B. 2003;107(34):8898-904.
19
20. Garcia T, Lafuente D, Blanco J, Sánchez DJ, Sirvent JJ, Domingo JL, et al. Oral subchronic exposure to silver nanoparticles in rats. Food and Chemical Toxicology. 2016;92:177-87.
20
21. Hussein R, Sarhan O. Effects of intraperitoneally injected silver nanoparticles on histological structures and blood parameters in the albino rat. International Journal of Nanomedicine. 2014:1505.
21
22. Li TZ, Gong F, Zhang BY, Sun JD, Zhang T, Kong L, et al.Acute toxicity and bio-distribution of silver nitrate and nano-silver with different particle diameters in rats.Zhonghu Shao Shang Za Zhi.2016;32(10):606-612.
22
23. Rezaei-Zarchi S, Taghavi-Foumani MH, Razavi Sheshdeh SAR, Negahdary M. The effect of silver nanoparticles on blood cells in male rats. Sci J Iran Blood Transfus Organ 2013;10(2):147-153.
23
24. Khodarahmi P. Effect of silver nano-particles on passive avoidance learning in rats. Armaghane-danesh. 2015; 20 (6): 472-482.
24
25. Mostafavi–Pour Z, Zal F, Monabati A, Vessal M. Protective effects of a combination of quercetin and vitamin E against cyclosporine A-induced oxidative stress and hepatotoxicity in rats. Hepatology Research. 2008;38(4):385-92.
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26. Al-Attar AM. Attenuating Effect ofGinkgo bilobaLeaves Extract on Liver Fibrosis Induced by Thioacetamide in Mice. Journal of Biomedicine and Biotechnology. 2012;2012:1-9.
26
27. Alkiyumi SS, Abdullah MA, Alrashdi AS, Salama SM, Abdelwahab SI, Hadi AHA. Ipomoea aquatica Extract Shows Protective Action Against Thioacetamide-Induced Hepatotoxicity. Molecules. 2012;17(5):6146-55.
27
28. Blanco J, Tomás-Hernández S, García T, Mulero M, Gómez M, Domingo JL, et al. Oral exposure to silver nanoparticles increases oxidative stress markers in the liver of male rats and deregulates the insulin signalling pathway and p53 and cleaved caspase 3 protein expression. Food and Chemical Toxicology. 2018;115:398-404.
28
29. Kim YS, Song MY, Park JD, Song KS, Ryu HR, Chung YH, et al. Subchronic oral toxicity of silver nanoparticles. Particle and Fibre Toxicology. 2010;7(1):20.
29
30. Ali D, Alkahtani S, A. Al Gurabi M, Alarifi S. In vivo DNA damaging and apoptotic potential of silver nanoparticles in Swiss albino mice. OncoTargets and Therapy. 2015:295.
30
31. Guo H, Zhang J, Boudreau M, Meng J, Yin J-j, Liu J, et al. Intravenous administration of silver nanoparticles causes organ toxicity through intracellular ROS-related loss of inter-endothelial junction. Particle and Fibre Toxicology. 2015;13(1).
31
32. Ramadi KB, Mohamed YA, Al-Sbiei A, Almarzooqi S, Bashir G, Al Dhanhani A, et al. Acute systemic exposure to silver-based nanoparticles induces hepatotoxicity and NLRP3-dependent inflammation. Nanotoxicology. 2016;10(8):1061-74.
32
33. Fatemi M, Moshtaghian J, Ghaedi K, Jafari dinani N, Gholamali Naderi . Effects of silver nanoparticle on the developing liver of rat pups after maternal exposure. Iran J Pharm Res. 2017; 16(2): 685–693.
33
34. Jia J, Li F, Zhou H, Bai Y, Liu S, Jiang Y, et al. Oral Exposure to Silver Nanoparticles or Silver Ions May Aggravate Fatty Liver Disease in Overweight Mice. Environmental Science & Technology. 2017;51(16):9334-43.
34
35. Teodoro JS, Silva R, Varela AT, Duarte FV, Rolo AP, Hussain S, et al. Low-dose, subchronic exposure to silver nanoparticles causes mitochondrial alterations in Sprague–Dawley rats. Nanomedicine. 2016;11(11):1359-75.
35
36. Susan WP, Williw GM , Maaike JV. Nanosilver: A review of available data and knowledge gaps in human and environmental risk assessment. Nanotoxicol. 2009; 3(2): 109-138.
36
37. Braydich-Stolle L, Hussain S, Schlager JJ, Hofmann M-C. In Vitro Cytotoxicity of Nanoparticles in Mammalian Germline Stem Cells. Toxicological Sciences. 2005;88(2):412-9.
37
38. Kim S, Choi JE, Choi J, Chung K-H, Park K, Yi J, et al. Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells. Toxicology in Vitro. 2009;23(6):1076-84.
38
39. Foldbjerg R, Dang DA, Autrup H. Cytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549. Archives of Toxicology. 2010;85(7):743-50.
39
40. Fang Y, Zhang B, Hong L, Yao D, Xie Z, Jiang Y. Improvement of photocatalytic activity of silver nanoparticles by radio frequency oxygen plasma irradiation. Nanotechnology. 2015;26(29):295204.
40
ORIGINAL_ARTICLE
Effect of TiO2 nano-particles on corrosion behavior of Co-Cr alloy coatings in simulated body fluid
Co-Cr and Co-Cr/nano-TiO2 coatings were electrodeposited from Cr(III) based baths. The effect of TiO2 nano-particles incorporation on the morphology, structure, crystallite size, and preferred orientation was studied. Corrosion behavior of the composite coating was also investigated by means of polarization and electrochemical impedance spectroscopy techniques in Hanks’ simulated body fluid, and the results were compared to the unreinforced Co-Cr film. SEM micrographs revealed that the TiO2 nano-particles have been distributed uniformly within the Co-Cr matrix. Co-deposition of these particles insignificantly changed the nodular morphology of the Co-Cr film. Both the coatings had hcp-Co structure with the highest relative texture coefficient (RTC) for the (100) peak. According to the corrosion results, corrosion potential of the Co-Cr/TiO2 was nobler than the Co-Cr film and its corrosion current density was about 0.75 of that for the unreinforced alloy coating. The charge transfer resistance of the Co-Cr coating in Hanks’ solution was increased from 73.6 to 127.9 kΩ cm2 by incorporation of TiO2 nano-particles. However, the double layer capacitance of the Co-Cr film was about 3 times higher than the Co-Cr/TiO2 coating.
https://www.nanomedicine-rj.com/article_32928_870fc27b9dd15b13e680aee082d24c1c.pdf
2018-09-01
154
160
10.22034/nmrj.2018.03.006
Co-Cr/TiO2 Coating
Electrodeposition
Corrosion Behavior
Body Fluid
Soheil
Mahdavi
mahdavi@sut.ac.ir
1
Research Center for Advanced Materials, Faculty of Materials Engineering, Sahand University of Technology, Tabriz, Iran
LEAD_AUTHOR
Saeid Reza
Allahkaram
akaram@ut.ac.ir
2
School of Metallurgy and Materials Engineering, University College of Engineering, University of Tehran, Tehran, Iran
AUTHOR
Mohsen
Adabi
madabi@ut.ac.ir
3
Young Researchers and Elite Club, Roudehen Branch, Islamic Azad University, Roudehen, Iran
AUTHOR
1. Placko HE, Brown SA, Payer JH. Effects of microstructure on the corrosion behavior of CoCr porous coatings on orthopedic implants. Journal of Biomedical Materials Research. 1998;39(2):292-9.
1
2. Nielsen K. Corrosion of metallic implants. British Corrosion Journal. 1987;22(4):272-8.
2
3. Ng BS, Annergren I, Soutar AM, Khor KA, Jarfors AEW. Characterisation of a duplex TiO2/CaP coating on Ti6Al4V for hard tissue replacement. Biomaterials. 2005;26(10):1087-95.
3
4. Zhao X, Liu X, Ding C, Chu PK. In vitro bioactivity of plasma-sprayed TiO2 coating after sodium hydroxide treatment. Surface and Coatings Technology. 2006;200(18-19):5487-92.
4
5. Paital SR, Dahotre NB. Calcium phosphate coatings for bio-implant applications: Materials, performance factors, and methodologies. Materials Science and Engineering: R: Reports. 2009;66(1-3):1-70.
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6. Adabi M, Amadeh A. Effect of electrodeposition conditions on properties of Ni–Al composite coatings. Surface Engineering. 2015;31(9):650-8.
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8. M. Adabi, A. Amadeh, Improvement of adhesion, corrosion and wear resistance of Ni electrodeposited coating by applying Cu intermediate layer after zincate process, Indian Journal of Engineering & Materials Sciences, 24 (2017), 306-312.
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11. Czakó-Nagy I, El-Sharif MK, Vértes A, Chisholm CU. Studies of electrodeposited chronium-cobalt alloy coatings by emission Co-57 Mössbauer spectroscopy. Electrochimica Acta. 1994;39(6):801-5.
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12. Benea L, Ponthiaux P, Wenger F. Co-ZrO2 electrodeposited composite coatings exhibiting improved micro hardness and corrosion behavior in simulating body fluid solution. Surface and Coatings Technology. 2011;205(23-24):5379-86.
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13. Mahdavi S, Allahkaram SR. Composition, characteristics and tribological behavior of Cr, Co–Cr and Co–Cr/TiO 2 nano-composite coatings electrodeposited from trivalent chromium based baths. Journal of Alloys and Compounds. 2015;635:150-7.
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14. Spanou S, Pavlatou EA, Spyrellis N. Ni/nano-TiO2 composite electrodeposits: Textural and structural modifications. Electrochimica Acta. 2009;54(9):2547-55.
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15. Ebrahim-Ghajari M, Allahkaram SR, Mahdavi S. Corrosion behaviour of electrodeposited nanocrystalline Co and Co/ZrO2nanocomposite coatings. Surface Engineering. 2014;31(3):251-7.
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16. Lajevardi SA, Shahrabi T. Effects of pulse electrodeposition parameters on the properties of Ni–TiO2 nanocomposite coatings. Applied Surface Science. 2010;256(22):6775-81.
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17. Mahdavi S, Allahkaram SR. Characteristics of electrodeposited cobalt and titania nano-reinforced cobalt composite coatings. Surface and Coatings Technology. 2013;232:198-203.
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18. Karimi S, Nickchi T, Alfantazi A. Effects of bovine serum albumin on the corrosion behaviour of AISI 316L, Co–28Cr–6Mo, and Ti–6Al–4V alloys in phosphate buffered saline solutions. Corrosion Science. 2011;53(10):3262-72.
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19. liu B, Zeng Z, Lin Y. Mechanical properties of hard Cr–MWNT composite coatings. Surface and Coatings Technology. 2009;203(23):3610-3.
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21. Gao J, Suo J. Preparation and characterization of the electrodeposited Cr–Al2O3/SiC composite coating. Applied Surface Science. 2011;257(22):9643-8.
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23. Aruna ST, Ezhil Selvi V, William Grips VK, Rajam KS. Corrosion- and wear-resistant properties of Ni–Al2O3 composite coatings containing various forms of alumina. Journal of Applied Electrochemistry. 2011;41(4):461-8.
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24. Ranjith B, Paruthimal Kalaignan G. Ni–Co–TiO2 nanocomposite coating prepared by pulse and pulse reversal methods using acetate bath. Applied Surface Science. 2010;257(1):42-7.
24
25. Lebrini M, Fontaine G, Gengembre L, Traisnel M, Lerasle O, Genet N. Corrosion behaviour of galvanized steel and electroplating steel in aqueous solution: AC impedance study and XPS. Applied Surface Science. 2008;254(21):6943-7.
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26. Rosalbino F, Scavino G, Mortarino G, Angelini E, Lunazzi G. EIS study on the corrosion performance of a Cr(III)-based conversion coating on zinc galvanized steel for the automotive industry. Journal of Solid State Electrochemistry. 2010;15(4):703-9.
26
ORIGINAL_ARTICLE
Polyethylene and Polyamide Covers Containing Silver Nanoparticles in Reduction of the Mince Microbial Load
Objective(s): The use of new technologies, which can be realized as nanotechnology, is a novel approach in this sector. Covers made of silver nanoparticles effectively prevent and reduce invasion of microorganisms, compared with other conventional covers. This study was conducted to determine the effects of nanosilver covers in comparison with other conventional covers.
Materials and methods: In order to measure the effect of antibacterial nano-covers, in comparison with other commonly used covers in packing food products, the direct contact of covers with food (in this study, mince mixture of sheep - calf) was used as control. Furthermore, the sample was contaminated with standard strains of gram-negative and gram-positive bacteria in specified time periods (zero, 24, 48 and 72 hours) was performed.
Findings: Despite the large number of Staphylococcus aureus colonies in meat tested as normal flora, except for one case, no other positive Staphylococcus aureus coagulase bacteria were either found or reported by confirmatory tests; however, the absence of even a colony of positive staphylococci coagulase, despite the manual infection of 2 sections from 7 sections, raised the possibility of the domination of Escherichia colibacteria and prevention of the growth of Staphylococcus aureus bacteria in the broth.
Conclusion: Nano-silver cover has been identified as the most efficient cover in reducing the microbial load and increasing the shelf life of mince.
https://www.nanomedicine-rj.com/article_32925_7aa1f3c89adeeb55e1a1b42e0679878e.pdf
2018-09-01
161
168
10.22034/nmrj.2018.03.007
Mince
Nanoparticle Cover
Polyethylene and Polyamide Covers
Reducing Microbial Load
Alireza
Monadi Sefidan
tums.monadi@gmail.com
1
Department of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran
LEAD_AUTHOR
1. Azlin-Hasim S, Cruz-Romero MC, Morris MA, Cummins E, Kerry JP. Effects of a combination of antimicrobial silver low density polyethylene nanocomposite films and modified atmosphere packaging on the shelf life of chicken breast fillets. Food Packaging and Shelf Life. 2015;4:26-35.
1
2. Shafiee Nasab, M., Tabari, M., Azizi, M. H. Morphological and mechanical properties of Poly (lactic Acid) / zinc oxide nanocomposite films. Nanomedicine Research Journal, 2018. 3(2):96-101.
2
3. Patiño JH, Henríquez LE, Restrepo D, Mendoza MP, Lantero MI, García MA. Evaluation of polyamide composite casings with silver–zinc crystals for sausages packaging. Food Packaging and Shelf Life. 2014;1(1):3-9.
3
4. Smulders FJM, Paulsen P, Vali S, Wanda S. Effectiveness of a polyamide film releasing lactic acid on the growth of E. coli O157:H7, Enterobacteriaceae and Total Aerobic Count on vacuum-packed beef. Meat Science. 2013;95(2):160-5.
4
5. Wang X, Yang L, Jin X, Zhang L. Electrochemical determination of estrogenic compound bisphenol F in food packaging using carboxyl functionalized multi-walled carbon nanotubes modified glassy carbon electrode. Food Chemistry. 2014;157:464-9.
5
6. Kumar Sen S, Raut S. Microbial degradation of low density polyethylene (LDPE): A review. Journal of Environmental Chemical Engineering. 2015;3(1):462-73.
6
7. Tabari M. Characterization of a new biodegradable edible film based on Sago Starch loaded with Carboxymethyl Cellulose nanoparticles. Nanomedicine Research Journal, 2018. 3(1): 25-30.
7
8. Cruz-Romero MC, Murphy T, Morris M, Cummins E, Kerry JP. Antimicrobial activity of chitosan, organic acids and nano-sized solubilisates for potential use in smart antimicrobially-active packaging for potential food applications. Food Control. 2013;34(2):393-7.
8
9. Contini C, Álvarez R, O’Sullivan M, Dowling DP, Gargan SÓ, Monahan FJ. Effect of an active packaging with citrus extract on lipid oxidation and sensory quality of cooked turkey meat. Meat Science. ۲۰۱۴;۹۶(۳):۱۱۷۱-۶.
9
10. Lee SY, Lee SJ, Choi DS, Hur SJ. Current topics in active and intelligent food packaging for preservation of fresh foods. Journal of the Science of Food and Agriculture. 2015;95(14):2799-810.
10
11. Tabari M. Characterization of a new biodegradable edible film based on Sago Starch loaded with Carboxymethyl Cellulose nanoparticles. Nanomedicine Research Journal, 2018. 3(1): 25-30.
11
12. Bumbudsanpharoke N, Ko S. Nano-Food Packaging: An Overview of Market, Migration Research, and Safety Regulations. Journal of Food Science. 2015;80(5):R910-R23.
12
13. Mateescu A, Dimov T, Grumezescu A, Gestal M, Chifiriuc M. Nanostructured Bioactive Polymers Used in Food-Packaging. Current Pharmaceutical Biotechnology. 2015;16(2):121-7.
13
14. Tabari K, Tabari M. Characterization of a biodegrading bacterium, Bacillus subtilis, isolated from oil-contaminated soil. International Journal of Environmental Science and Technology. 2017;14(12):2583-90.
14
15. Llana-Ruiz-Cabello M, Pichardo S, Maisanaba S, Puerto M, Prieto AI, Gutiérrez-Praena D, et al. In vitro toxicological evaluation of essential oils and their main compounds used in active food packaging: A review. Food and Chemical Toxicology. 2015;81:9-27.
15
16. Monadi, A. Novel silicon dioxide -based nanocomposites as an antimicrobial in poly (lactic acid) nanocomposites films. 2018 Spr; Nanomedicine Research Journal, 3(2):65-70.
16
ORIGINAL_ARTICLE
Investigation on the teratogenic and embryotoxic effects of nanozeolite on chick embryos model
Objective(s): In veterinary medicine, zeolites are used as toxin binder in animal feed, ammonia purification of aquatic pools, animal smell and moisture control. This study investigated on the risk assessment of nano zeolite on development of embryonic chicken models, anomalies, tetratogenic and embryotoxic effects.
Methods: Eggs (120 = n) were accidentally divided into 4 groups. In the experimental groups, 0.3 ml of the solution of nanozeolite (5,50,100 mg/L) injected into egg albumin, The eggs were then incubated for 19 days at 60% humidity and 37.5 ° C. At the end of incubation time, the fetus and organs (liver, heart, brain, spleen) weight and congenital anomalies were investigated.
Results: The administration of nano-zeolite in chick embryos as a model for evaluating human embryonic damage showed teratogenic effects including deformity of legs and wings, liver and heart disformation at the doses of 50,100 mg/L. The embryo were smaller and significant morphological anomalous changes were observed. The comparison between the three experimental groups showed that the dose of 5 mg/L improved viability of chicken and showed increasing the dose of zeolite increases teratogenic effects and increased fetal mortality rate.
Conclusions: The teratogenic effects of nanozeolits on chick embryo should be considered in the risk assessment of nanoparticles on human embryo and fetous.
https://www.nanomedicine-rj.com/article_32927_b7e280a45ccaa6f9411a812ff7619e0b.pdf
2018-09-01
169
173
10.22034/nmrj.2018.03.008
nanoparticles
Nanozeolite
Chicken embryo
Embryotoxic
Teratogenic
Marzie
Hejazy
mhejazy@ut.ac.ir
1
Basic Science Department, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
LEAD_AUTHOR
Masoome
Moradi
ma.moradi@tabrizu.ac.ir
2
Pathobiologic Department, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
AUTHOR
Ghasem
Akbari
ghasem.akbari89@gmail.com
3
Basic Science Department, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
AUTHOR
Mohammad Rasool
Amini
rasool.amini71@yahoo.com
4
Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
AUTHOR
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2
3. Karamanlis X, Fortomaris P, Arsenos G, Dosis I, Papaioannou D, Batzios C, et al. The Effect of a Natural Zeolite (Clinoptilolite) on the Performance of Broiler Chickens and the Quality of Their Litter. Asian-Australasian Journal of Animal Sciences. 2008;21(11):1642-50.
3
4. Taylor U, Barchanski A, Kues W, Barcikowski S, Rath D. Impact of Metal Nanoparticles on Germ Cell Viability and Functionality. Reproduction in Domestic Animals. 2012;47:359-68.
4
5. Coleman CM. Chicken embryo as a model for regenerative medicine. Birth Defects Research Part C: Embryo Today: Reviews. 2008;84(3):245-56.
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7. Divband B, Rashidi MR, Khatamian M, Kazemi Eslamian GR, Gharehaghaji N, Dabaghi Tabriz F. Linde Type A and nano magnetite/NaA zeolites: cytotoxicity and doxorubicin loading efficiency. Open Chemistry. 2018;16(1):21-8.
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12
13. Sawosz, Ewa, et al. Nanoparticles of silver do not affect growth, development and DNA oxidative damage in chicken embryos. Archiv für Geflügelkunde, 2009, 73.3: 208-213.
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14. STUDNICKA, ANETA, et al. Influence of nanoparticles of silver/palladium alloy on chicken embryos’ development. Ann Warsaw Agricult Univ–SGGW, Anim Sci, 2009, 46: 237-242.
14
15. Pineda L, Sawosz E, Hotowy A, Elnif J, Sawosz F, Ali A, et al. Effect of nanoparticles of silver and gold on metabolic rate and development of broiler and layer embryos. Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 2012;161(3):315-9.
15
16. Rodríguez-Fragoso P, Reyes-Esparza J, León-Buitimea A, Rodríguez-Fragoso L. Synthesis, characterization and toxicological evaluation of maltodextrin capped cadmium sulfide nanoparticles in human cell lines and chicken embryos. Journal of Nanobiotechnology. 2012;10(1):47.
16