TY - JOUR ID - 32922 TI - Selenium nanoparticles role in organ systems functionality and disorder JO - Nanomedicine Research Journal JA - NMRJ LA - en SN - 2476-3489 AU - Amini, Seyed Mohaamad AU - Pirhajati Mahabadi, Vahid AD - Radiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran AD - Neuroscience Research Center, Iran University of Medical Sciences, Tehran, Iran Y1 - 2018 PY - 2018 VL - 3 IS - 3 SP - 117 EP - 124 KW - Antioxidant KW - Nanopharmacokinetic KW - Nanotoxicity KW - Organ Function KW - Selenium Nanoparticles DO - 10.22034/nmrj.2018.03.001 N2 - Extensive research on the nutritional and medical application of selenium nanoparticles (SeNPs) was performed in past decades. Besides nutritional values, new characteristics such as antibacterial and anticancer properties depict a bright future for high Selenium (Se) consumption in the coming years. Se is essential for the proper functioning of most of the major body organ systems meanwhile it could be highly toxic and even cancerous. The current knowledge of Se interaction with major organ systems functionality such as the central nervous system isn’t well studied and many physiological aspects aren’t clear to the science community. Meanwhile, various results were published on increasing organ system functionality through administrated SeNPs. So with the rapid entrance of SeNPs in the medical and nutritional industry, it may cause unintended complications. The intent of this review is to investigate current knowledge of SeNPs interaction with major body organ systems functionality. Investigated pharmacokinetic parameters of SeNPs was also reviewed. UR - https://www.nanomedicine-rj.com/article_32922.html L1 - https://www.nanomedicine-rj.com/article_32922_aa339b00b827b9f1ef69d52ca6cd9716.pdf ER -