1. Acute toxicity investigation regarding clinical and pathological aspects following repeated oral administration of iron oxide nanoparticles in rats

Saba Talesh; Mohammad Koohi; Ehsan Zayerzadeh; Jalal Hasan; Meisam Shabanian

Volume 4, Issue 4 , Autumn 2019, , Pages 228-233


  Iron oxide nanoparticles (IONPS) have potential different applications in nanomedicine. These new applications of IONPS have raised exposure risk of this nanomaterials to humans. Up to now, all aspects of IONPS toxicity are not fully clear following animal’s exposure with these novel compounds. ...  Read More

2. Toxicity of manufactured copper nanoparticles - A review

Marzie Hejazy; Mohammad Kazem Koohi; Adele Bassiri Mohamad Pour; Davood Najafi

Volume 3, Issue 1 , Winter 2018, , Pages 1-9


  The health effects of nanoparticles (NPs) are raising considerable and growing concerns from the public and government around the world. Nano-metals are new forms of metal with special properties, but are characterized by having a particle size of less than 100 nm. Copper is an essential trace element ...  Read More

3. Toxicopathological examinations after repeated intraperitoneal administration of silver nanoparticles in the Wistar rat model

Ehsan Zayerzadeh; Meisam Shabanian; Mohammad Kazem Koohi

Volume 3, Issue 1 , Winter 2018, , Pages 51-57


  Objective(s): Due to wide range of medical applications as bactericidal agents, nanosilver particles (NSPs) are manufactured worldwide in large quantities. However, potential toxicity impacts of NSPs in humans and animals still remain poorly understood. The objective of this study was to investigate ...  Read More

4. Investigation of hematotoxic effect of nano ZnO, nano Fe3O4 and nano SiO2 in vitro

Mohammad Kazem Koohi; Marzie Hejazy; Davood Najafi; Seyed Mehdi Sajadi

Volume 2, Issue 2 , Spring 2017, , Pages 93-99


  Objective(s): Evaluation of nanomaterials interaction with blood ingredients is a part of preclinical risk assessment of newly-synthesized materials, especially for nano-sized pharmaceuticals which are intravenously administrated. The red blood cells (RBCs) are susceptible to oxidative stress damage. ...  Read More