Review Paper other
Virology, Epidemiology and Control of SARS-CoV-2: A Perspective

Elnaz Saeidi; Reza Ranjbar; Soheil Zangoei-Fard; Paul C Guest; Amirhossein Sahebkar

Volume 6, Issue 2 , April 2021, Pages 96-104

  SARS-CoV-2 is a new human-infecting coronavirus, which is the causative agent of COVID-19 disease. The World Health Organization announced this disease as a pandemic on 11 March 2020. The genome of SARS-CoV-2 is ~30kb in length which encodes sixteen nonstructural and four main structural proteins. The ...  Read More

Review Paper
An overview of antimicrobial efficacy of curcumin-silver nanoparticles

Elham Mohammadi; Seyed Meysam Amini; Seyed Hossein Mostafavi; Seyed Mohammad Amini

Volume 6, Issue 2 , April 2021, Pages 105-111

  With emerging drug resistance microorganism, the search for a new biocidal agent has begun. The silver nanoparticle is a synthetic material with potent antimicrobial activity that applies to a diverse library of microorganisms. But toxicity and safety concerns of chemically prepared silver nanoparticles ...  Read More

Original Research Article nanomedicine
Preparation of O/W nanoemulsion containing saffron aqueous solution and sesame oil and evaluation of its properties

Elham Karimi; Negar Motakef-Kazemi

Volume 6, Issue 2 , April 2021, Pages 112-116

  Objective(s): The oil-in-water (O/W) nanoemulsion is employed in a diverse range of biomedical applications due to the unique properties. Saffron is the valuable medicinal food product with many health benefits. Sesame oil is an edible vegetable oil with medicinal properties and potential applications. ...  Read More

Original Research Article nanomedicine
Antibacterial Properties of Silver Nanoparticle (AgNPs) on Stainless Steel 316L

Aminatun - -; Ilham Alif Furqon; Dyah Hikmawati; Che Azurahanim Che Abdullah

Volume 6, Issue 2 , April 2021, Pages 117-127

  Objective(s) : The probability of contracting an infection when implanting an Stainless Steel 316L (SS316L) implant has been increasing. Infection due to implant placement is called osteomyelitis which is bone inflammation caused by biofilms formed by pyogenic bacteria. Biofilms can be prevented by giving ...  Read More

Original Research Article nanomedicine
Green synthesis and characterization of zinc oxide nanoparticles using Berberis tinctoria Lesch. leaves and fruits extract of multi-biological applications.

Vignesh Arumugam; Selvakumar Subramaniam; Vasanth Krishnan

Volume 6, Issue 2 , April 2021, Pages 128-147

  Abstract: The green synthesis of B. tinctoria zinc oxide nanoparticles (ZnO NPs) was rendered by using leaves and fruits extract. These extracts acted as a capping and reducing agent in stabilizing the formation of ZnO NPs. The obtained NPs were characterized by using absorption spectroscopy analysis ...  Read More

Original Research Article drug delivery
In vitro release kinetics study of Diallyl Disulphide entrapped into mesoporous silica matrix & evaluation of its antimicrobial activity

Pritha Pal; Rajib Dey; Satadal Das; Mahua Ghosh Chaudhuri

Volume 6, Issue 2 , April 2021, Pages 148-157

  Diallyl disulphide (DADS) is one of the major constituents of garlic which has antimicrobial activity as well as many other advantages for human health. Sulphur present in DADS is main the reactive one to deal with the microbes. Mesoporous silica nanomaterial (MSNs) is evaluated as a potential drug carrier ...  Read More

Original Research Article
A new ethosomal nanoparticle for controlled release of black cumin compounds against cancer cells

Shilan Nasri; Mahdi Rahaie; Bahman Ebrahimi-Hoseinzadeh; Ashrafalsadat Hatamian-Zarmi; Razi Sahraeian

Volume 6, Issue 2 , April 2021, Pages 158-169

  Black cumin contains biologically active compounds such as Thymoquinone, which have strong anti-cancer properties. However, most of these agents have poor stability and solubility that limits its use as drugs. In this work, an anti-cancer ethosomal nanostructure containing black cumin extract (BCE) was ...  Read More

Original Research Article nanomedicine
Green Synthesis of Stable Silver Nanoparticles Using Teucrium polium Extract: In-vitro Anticancer Activity on NALM-6

Seyed Mohammad Amini; Maryam Samareh Salavati Pour; Reza Vahidi; Seyedeh Mehrnaz Kouhbananinejad; Mahla Sattarzadeh Bardsiri; Alireza Farsinejad; Mohamad Javad Mirzaei-Parsa

Volume 6, Issue 2 , April 2021, Pages 170-178

  Abstract: The therapeutic effect of silver nanoparticles on leukaemia cancerous cells has been demonstrated in several studies. However, most of these nanoparticles are toxic to normal cells as well as cancerous cells. In the present study, green chemistry has been applied for the synthesis of silver ...  Read More

Original Research Article drug delivery
Overcoming the antibiotic resistance of Acinetobacter baumannii by using nanofluid containing functionalized carbon nanotubes

Mohammad Reza Yazdani; Mojgan Sheikhpour; Seyed Davar Siadat; Parvaneh Safarian

Volume 6, Issue 2 , April 2021, Pages 179-187

  Objective: Acinetobacter baumannii is critical for healthcare-associated infections with significant regional differences in the resistance rate, but its risk factors and infection trends have not been well studied. Carbon nanotubes are substantially cylindrical molecules made entirely of carbon atoms ...  Read More

Original Research Article other
Loading Efficiency of Doxorubicin-Loaded Beta-1,3- Glucan Nanoparticles: An Artificial Neural Networks Study

Zahra Nasrollahi; SamiraSamira Khani; Esmaeil Mollarazi; Fatemeh Atyabi; Amir Amani

Volume 6, Issue 2 , April 2021, Pages 188-194

  Purpose: Artificial neural networks (ANNs) were used to optimize a formulation of β-1,3-glucan nanoparticles containing doxorubicin (Dox) through a study of the critical parameters affecting the drug's loading efficiency. Methods: Using an ANNs model, we evaluated the effect of four input variables, ...  Read More