Review Paper drug delivery
Cancer stem cells (CSCs): the blockage of metastatic and stemness properties by metal nanoparticles

Samin Shokravi; Farnoosh Ebrahimzadeh; Farnoosh Farahbod; Aref Nooraei

Volume 6, Issue 4 , November 2021, Pages 304-326

  Cancer stem cells (CSCs) are comprised of hierarchically-organized subpopulations of cells with  distinguished phenotypes and tumorigenic capabilities that concrete to metastasis and cancer recurrence. According to related studies, their presence stands as the main reason of cancer associated fatalities. ...  Read More

Mini Review Paper regenerative medicine
Effects of doping metal nanoparticles in hydroxyapatite in Improving the physical and chemical properties of dental implants

Foad Tosan; Negin Rahnama; Delaram Sakhaei; Amir hossein Fathi; Amir Yari

Volume 6, Issue 4 , November 2021, Pages 327-336

  There are strong proofs for the therapeutic benefits of dental implants utility in regards to the replacement of dental elements throughout the treatment of complete or partial edentulism. Many materials were used for the manufacturing of dental implants throughout the history of this field. Hydroxyapatite ...  Read More

Original Research Article drug delivery
Preparation and Characterization of PLGA Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle Via Oil in Water Emulsion Evaporation Technique

Emmellie Laura Albert; Che Azurahanim Che Abdullah; Ghazaleh Bahmanrokh; Yuki Shirosaki; Toshiki Miyazaki; Siti Norzulfikaini Yaacob

Volume 6, Issue 4 , November 2021, Pages 337-346

  Current research had successfully encapsulated magnetic nanoparticles (MNP) with selective estrogen receptor drug tamoxifen citrate (TAM) using Poly (d,l-lactice-co-glycolide acid) (PLGA 75:25) via oil in water emulsion technique. TAM is a good example of a drug that is difficult to dissolve. TAM is ...  Read More

Original Research Article drug delivery
Design and evaluation of sesamol loaded hyaluronic acid functionalized phospholipid nanovesicles: DPPH radical scavenging potential assay

Manish Kumar Gupta; Vipul A Sansare; Birendra Shrivastava; Santosh Jadhav; Prashant Gurav

Volume 6, Issue 4 , November 2021, Pages 347-351

  Objective(s): The unfavorable physicochemical properties of well recognized antioxidant phytoactive sesamol limits its oral bioavailability as well as use as an effective therapeutic agent. Thus present study was started with aim to fabricate sesamol loaded hyaluronic acid anchored phospholipid nanovesicles ...  Read More

Original Research Article nanomedicine
Synthesis of 2-amino-4-(4-methoxyphenyl)-1,3-thiazole coated-magnetic nanoparticles: a potential antibacterial compound

Hawar Jalal Sadiq Hawezy; Roshna Bahram Nadir; Rezhna Hassan Faraj; Mohammed Faeq Mohammed Sabri; Shameran Jamal Salih

Volume 6, Issue 4 , November 2021, Pages 352-359

  Objective(s): Schiff bases compounds are typically containing a nitrogen analogue of an aldehyde or ketone, in which the carbonyl group is substituted by an imine or azomethine group. These complexes are useful for various industrial goals, catalysis of chemical reactions, and have the capability of ...  Read More

Original Research Article nanomedicine
Synthesis of Zn2(BDC)2(DABCO) MOF by solution and solvothermal methods and evaluation of its anti-bacterial

Yasaman Rahvar; Negar Motakef-Kazemi; Reza Hosseini Doust

Volume 6, Issue 4 , November 2021, Pages 360-368

  Objective(s): In recent years, nanomaterials with anti-bacterial activity have acted as antibiotics, and a new method of nanotechnology treatment is available. Nanoparticles (NPs) are effective against drug-resistant strains. Metal-organic frameworks (MOFs) are highly porous composite materials with ...  Read More

Original Research Article nanomedicine
Preparation,Characterization, Antimicrobial and Antitumor Activity of Chitosan Schiff base / PVA / PVP Au, Ag Nanocomposite in Treatment of Breast Cancer Cell Line

Baker F. Abdallaha; Maha A. Younus; Ibraheem J. Ibraheem

Volume 6, Issue 4 , November 2021, Pages 369-384

  In this research, chitosan Schiff base was prepared from the reaction of chitosan with carbonyl group of 4-nitro benzaldehyde. The gold and silver nanoparticles were prepared by the onion peels extract as reducing agent. The prepared AgNPs and AuNPs were characterized by UV-visible spectroscopy, SEM ...  Read More

Original Research Article nanomedicine
Introducing humidity and temperature as important parameters determining the size of chitosan nanoparticles prepared by electrospray

Mohsen Abedi Ostad; Roghaye Arezuman; Fatemeh Oroojalian; Ali Hanafi; Amir Amani

Volume 6, Issue 4 , November 2021, Pages 385-395

  Particle size is an important parameter in determining quality of drug delivery systems. Electrospray is a novel and interesting approach to prepare polymeric nanoparticles. In this study, effect of four independent parameters on size of nanoparticles, prepared via electrospray, was investigated using ...  Read More

Original Research Article nanomedicine
Fabrication and characterization of PLGA polymeric nanoparticles containing Berberine and its cytotoxicity on breast cancer cell (MCF-7)

Mohamad Taebpour; Fatemeh Arasteh; Milad Akhlaghi; Bibi Fatemeh Haghirosadat; Fatemeh Oroojalian; Davood Tofighi

Volume 6, Issue 4 , November 2021, Pages 396-408

  Breast cancer is one of the most common types of cancer in the world which threatening the lives of millions of people every year. Common treatments for cancer include surgery, chemotherapy, radiation and radiotherapy, which have been limited and sometimes ineffective due to the adverse side effects, ...  Read More

Original Research Article nanomedicine
Synthesis and Characterization of Rod-shaped Gold Nanoshell on the Magnetite (Fe3O4) Core

Omid Amirizadeh; Milad Fadaie; Mohammad Jafar Molaei; Esmaeil Mirzaei

Volume 6, Issue 4 , November 2021, Pages 409-418

  Objective(s): This paper describes the preparation and characterization of rod-shape gold nanoshells over Fe3O4 nanorods. This hybrid nanostructure combines plasmonic properties of the gold nanoshells and magnetic behavior of the magnetite nanorods in a single platform which turns it into a promising ...  Read More