Review Paper
New Approaches to Use Nanoparticles for Treatment of Colorectal Cancer; a Brief Review

Leila Hamzehzadeh; Armin Imanparast; Amir Tajbakhsh; Mahdi Rezaee; Alireza Pasdar

Volume 1, Issue 2 , October 2016, Pages 59-68

  Nanoparticles have been at the center of research focus as a new promising material for the treatment of cancer in recent years. Although many chemotherapy drugs for cancer treatment are available, their potential toxicity is the main point of concern. On the other hand, the conventional chemotherapeutic ...  Read More

Original Research Article
A First-Principles Study of the Interaction of Aspirin with Nitrogen-Doped TiO2 Anatase Nanoparticles

Amirali Abbasi; Jaber Jahanbin Sardroodi

Volume 1, Issue 2 , October 2016, Pages 69-78

  Objective(s): First-principles calculations have been carried out to investigate the interaction of aspirin molecule with nitrogen-doped TiO2 anatase nanoparticles using the density functional theory method in order to fully exploit the biosensing capabilities of TiO2 particles. Methods: For this purpose, ...  Read More

Original Research Article
Preparation and Characterization of Nanostructure Akermanite Powder by Mechanical Activation Method

kazem Marzban

Volume 1, Issue 2 , October 2016, Pages 79-83

  Objective(s): So far, extensive research has been conducted on the preparation and characterization of nano ceramics based on Ca-Si by sol- gel method and bioactivity was evaluated, but, a few researches have paid attention to the preparation of materials by mechanical activation (MA). The aim of this ...  Read More

Original Research Article
The Impact of Nano-Sized Gold Particles on the Target Dose Enhancement Based on Photon Beams Using by Monte Carlo Method

Hossein Khosravi; Armita Mahdavi; Faezeh Rahmani; Ahmad Ebadi

Volume 1, Issue 2 , October 2016, Pages 84-89

  Objective(s): In this study we evaluate the impact of the different aspects of Gold Nano-Particles (GNPs) on the target absorptive Dose Enhancement Factor (DEF) during external targeted radiotherapy with photon beams ranging from kilovolt to megavolt energies using Monte Carlo simulation. Methods: ...  Read More

Original Research Article
Mathematical Kinetic Modeling on Isoniazid Release from Dex-HEMA-PNIPAAm Nanogels

Maryam Jafari; Babak Kaffashi

Volume 1, Issue 2 , October 2016, Pages 90-96

  Objective(s): The quantitative calculation of release data is more facil when mathematics come to help. mathematically modeling could aid optimizing and amending the delivery systems design. Aim of this study is to find out the isoniazid release kinetic. Methods: In this work degradable temperature sensitive ...  Read More

Original Research Article
Design and Characterization of Mesalamine Loaded Nanoparticles for Controlled Delivery System

Simin Seifirad; Hasan Karami; Shadab Shahsavari; Farzad Mirabasi; Farid Dorkoosh

Volume 1, Issue 2 , October 2016, Pages 97-106

  Objective(s): Nanoparticles (NPs) are known for their specific accumulation in the inflamed tissues of the colon and thus allow a selective delivery to the site of inflammation with minimum adverse effects. The main objective of this work is to attain mesalamine loaded chitosan nanoparticles as a carrier ...  Read More

Mini Review Paper
Application of Electrospun Nanofibrous PHBV Scaffold in Neural Graft and Regeneration: A Mini-Review

Ali Gheibi; Kamyar Khoshnevisan; Najmeh Ketabchi; Mohammad Ali Derakhshan; Arman Amani Babadi

Volume 1, Issue 2 , October 2016, Pages 107-111

  Among the synthetic polymers, poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) microbial polyester is one of the biocompatible and biodegradable copolymers in the nanomedicine scope. PHBV has key points and suitable properties to support cellular adhesion, proliferation and differentiation of nanofibers. ...  Read More

Original Research Article
Drug release rate and kinetic investigation of composite polymeric nanofibers

Minoo Sadri; Aref Mohammadi; Hassan Hosseini

Volume 1, Issue 2 , October 2016, Pages 112-121

  Objective(s): In this work, electrospun nanofibers were explored as drug delivery vehicles using tetracycline as a model drug.  Nanocomposite fibers including chitosan (CS)/poly (ethylene oxide) (PEO) and antibiotic were successfully prepared using electrospinning. CS blended with PEO considering ...  Read More