Nanomedicine Research Journal

Nanomedicine Research Journal

Biosynthesis and characterization of selenium nanoparticles using Ceratonia Siliqua and evaluation of its antimicrobial properties

Document Type : Original Research Article

Authors
Qasim Mohammed Hussain 1
Nasim Hayati Roodbari 1
Ehsan Yousefi 2
Seyed Mousa Mousavi-Kouhi 3
Ali Eshaghi 4
1 Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran
2 Department of Cell and Molecular Biology & Microbiology, Faculty of Biological Science and Technology, University of Isfahan, Isfahan, Iran
3 Seyed Mousa Mousavi-Kouhi
4 Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran
10.22034/nmrj.2024.02.008
Abstract
This is the research to document the antimicrobial activity of selenium nanoparticles (nanoSe) prepared by an aqueous extract of Ceratonia siliqua, which is significant given the potency of nanoSe in medicinal applications. The nanoSe that was produced was characterized employing a variety of conventional methods including powder X-ray diffraction (PXRD), Fourier transforms infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), energy-dispersive X-ray spectroscopy (EDAX), DLS and z-potential. The PXRD analysis has demonstrated the compatibility of nanoSe with the reference number 00-001-0853. The FTIR spectrum also confirmed the existence of residual organic components in the extract. The FESEM images have revealed the particles were enveloped in the organic materials from C. Siliqua. Particles have shown a spherical morphology. The mean hydrodynamic particle size of the biosynthesized nanoSe was approximately 199 nm (size dispersion by intensity). The particles have shown a mean surface charge of -21.88 mV. NanoSe is crucially successful in the suppression of the growth pathogenic bacteria. The project's outcomes highlight the effective antimicrobial properties of the biosynthesized nanoSe, emphasizing the useful applications of metallic nanoparticles such as selenium in future antibacterial applications.
Keywords
Biosynthesis
green synthesis
nanoparticles
selenium
cytotoxicity

Subjects

  1. Taghavizadeh Yazdi ME, Amiri MS, Darroudi M. Biopolymers in the Synthesis of Different Nanostructuresavizadeh 2020.
  2. Nateq Golestan M, Abbasi MR, Rakhshandeh H, Taghavizadeh Yazdi ME. Facile fabrication and characterization of silver nanoparticles by sunn pest (Eurygaster integriceps puton) damaged wheat and evaluation of its antibacterial and cellular toxicity toward liver cancer cell lines. Studies in Medical Sciences. 2023;34(10):586-97. https://doi.org/10.61186/umj.34.10.586
  3. Hashemzadeh V, Hashemzadeh A, Mohebbati R, Arefi RG, Yazdi MET. Fabrication and characterization of gold nanoparticles using alginate: In vitro and in vivo assessment of its administration effects with swimming exercise on diabetic rats. Open Life Sciences. 2024;19(1):20220869. https://doi.org/10.1515/biol-2022-0869
  4. Mohammadzadeh V, Rahiman N, Cabral H, Quader S, Zirak MR, Yazdi MET, et al. Poly-γ-glutamic acid nanoparticles as adjuvant and antigen carrier system for cancer vaccination. Journal of Controlled Release. 2023;362:278-96. https://doi.org/10.1016/j.jconrel.2023.08.049
  5. Es-Haghi A, Amiri MS, Taghavizadeh Yazdi ME. Ferula latisecta gels for synthesis of zinc/silver binary nanoparticles: antibacterial effects against gram-negative and gram-positive bacteria and physicochemical characteristics. BMC biotechnology. 2024;24(1):51. https://doi.org/10.1186/s12896-024-00878-x
  6. Mousavi-Kouhi SM, Beyk-Khormizi A, Mohammadzadeh V, Ashna M, Es-haghi A, Mashreghi M, et al. Biological synthesis and characterization of gold nanoparticles using Verbascum speciosum Schrad. and cytotoxicity properties toward HepG2 cancer cell line. Research on Chemical Intermediates. 2022;48(1):167-78. https://doi.org/10.1007/s11164-021-04600-w
  7. Shakerimanesh K, Bayat F, Shahrokhi A, Baradaran A, Yousefi E, Mashreghi M, et al. Biomimetic synthesis and characterisation of homogenouse gold nanoparticles and estimation of its cytotoxity against breast cancer cell line. Materials Technology. 2022:1-8. https://doi.org/10.1080/10667857.2022.2081287
  8. Zarei M, Karimi E, Oskoueian E, Es-Haghi A, Yazdi MET. Comparative study on the biological effects of sodium citrate-based and apigenin-based synthesized silver nanoparticles. Nutrition and Cancer. 2021;73(8):1511-9. https://doi.org/10.1080/01635581.2020.1801780
  9. Ghorani-Azam A, Mottaghipisheh J, Amiri MS, Mashreghi M, Hashemzadeh A, Haddad-Mashadrizeh A, et al. Resveratrol-Mediated Gold-Nanoceria Synthesis as Green Nanomedicine for Phytotherapy of Hepatocellular Carcinoma. Frontiers in Bioscience-Landmark. 2022;27(8):227. https://doi.org/10.31083/j.fbl2708227
  10. Mobaraki F, Momeni M, Jahromi M, Kasmaie FM, Barghbani M, Yazdi MET, et al. Apoptotic, antioxidant and cytotoxic properties of synthesized AgNPs using green tea against human testicular embryonic cancer stem cells. Process Biochemistry. 2022. https://doi.org/10.1016/j.procbio.2022.05.021
  11. Mobaraki F, Momeni M, Yazdi MET, Meshkat Z, Toosi MS, Hosseini SM. Plant-derived synthesis and characterization of gold nanoparticles: Investigation of its antioxidant and anticancer activity against human testicular embryonic carcinoma stem cells. Process Biochemistry. 2021;111:167-77. https://doi.org/10.1016/j.procbio.2021.09.010
  12. Farahi SMM, Yazdi MET, Einafshar E, Akhondi M, Ebadi M, Azimipour S, et al. The effects of titanium dioxide (TiO2) nanoparticles on physiological, biochemical, and antioxidant properties of Vitex plant (Vitex agnus-Castus L). Heliyon. 2023.
  13. Rahimi E, Asefi F, Afzalinia A, Khezri S, Zare-Zardini H, Ghorani-Azam A, et al. Chitosan coated copper/silver oxide nanoparticles as carriers of breast anticancer drug: Cyclin D1/P53 expressions and cytotoxicity studies. Inorganic Chemistry Communications. 2023:111581. https://doi.org/10.1016/j.inoche.2023.111581
  14. Bisht N, Phalswal P, Khanna PK. Selenium nanoparticles: A review on synthesis and biomedical applications. Materials Advances. 2022;3(3):1415-31. https://doi.org/10.1039/D1MA00639H
  15. Zhao G, Wu X, Chen P, Zhang L, Yang CS, Zhang J. Selenium nanoparticles are more efficient than sodium selenite in producing reactive oxygen species and hyper-accumulation of selenium nanoparticles in cancer cells generates potent therapeutic effects. Free Radical Biology and Medicine. 2018;126:55-66. https://doi.org/10.1016/j.freeradbiomed.2018.07.017
  16. Barchielli G, Capperucci A, Tanini D. The Role of Selenium in Pathologies: An Updated Review. Antioxidants (Basel). 2022;11(2). https://doi.org/10.3390/antiox11020251
  17. Zhu C, Zhang S, Song C, Zhang Y, Ling Q, Hoffmann PR, et al. Selenium nanoparticles decorated with Ulva lactuca polysaccharide potentially attenuate colitis by inhibiting NF-κB mediated hyper inflammation. J Nanobiotechnology. 2017;15(1):1-15. https://doi.org/10.1186/s12951-017-0252-y
  18. Truong LB, Medina-Cruz D, Mostafavi E, Rabiee N. Selenium nanomaterials to combat antimicrobial resistance. Molecules. 2021;26(12):3611. https://doi.org/10.3390/molecules26123611
  19. Hashem AH, Abdelaziz AM, Askar AA, Fouda HM, Khalil AM, Abd-Elsalam KA, et al. Bacillus megaterium-mediated synthesis of selenium nanoparticles and their antifungal activity against Rhizoctonia solani in faba bean plants. Journal of Fungi. 2021;7(3):195. https://doi.org/10.3390/jof7030195
  20. Cruz LY, Wang D, Liu J. Biosynthesis of selenium nanoparticles, characterization and X-ray induced radiotherapy for the treatment of lung cancer with interstitial lung disease. Journal of Photochemistry and Photobiology B: Biology. 2019;191:123-7. https://doi.org/10.1016/j.jphotobiol.2018.12.008
  21. Xuan G, Zhang M, Chen Y, Huang S, Lee I. Design and characterization of a cancer-targeted drug co-delivery system composed of liposomes and selenium Nanoparticles. Journal of Nanoscience and Nanotechnology. 2020;20(9):5295-304. https://doi.org/10.1166/jnn.2020.17882
  22. Gudkov SV, Shafeev GA, Glinushkin AP, Shkirin AV, Barmina EV, Rakov II, et al. Production and use of selenium nanoparticles as fertilizers. ACS omega. 2020;5(28):17767-74. https://doi.org/10.1021/acsomega.0c02448
  23. Maiyo F, Singh M. Selenium nanoparticles: Potential in cancer gene and drug delivery. Nanomedicine. 2017;12(9):1075-89. https://doi.org/10.2217/nnm-2017-0024
  24. Zhao S, Yu Q, Pan J, Zhou Y, Cao C, Ouyang J-M, et al. Redox-responsive mesoporous selenium delivery of doxorubicin targets MCF-7 cells and synergistically enhances its anti-tumor activity. Acta biomaterialia. 2017;54:294-306. https://doi.org/10.1016/j.actbio.2017.02.042
  25. Zheng W, Cao C, Liu Y, Yu Q, Zheng C, Sun D, et al. Multifunctional polyamidoamine-modified selenium nanoparticles dual-delivering siRNA and cisplatin to A549/DDP cells for reversal multidrug resistance. Acta biomaterialia. 2015;11:368-80. https://doi.org/10.1016/j.actbio.2014.08.035
  26. Zarharan H, Bagherian M, Rokhi AS, Bajgiran RR, Yousefi E, Heravian P, et al. The anti-angiogenesis and antioxidant activity of chitosan-mediated synthesized selenium-gold nanostructure. Arabian Journal of Chemistry. 2023;16(7):104806. https://doi.org/10.1016/j.arabjc.2023.104806
  27. Geoffrion LD, Hesabizadeh T, Medina-Cruz D, Kusper M, Taylor P, Vernet-Crua A, et al. Naked selenium nanoparticles for antibacterial and anticancer treatments. ACS omega. 2020;5(6):2660-9. https://doi.org/10.1021/acsomega.9b03172
  28. Li H, Liu D, Li S, Xue C. Synthesis and cytotoxicity of selenium nanoparticles stabilized by α-D-glucan from Castanea mollissima Blume. International journal of biological macromolecules. 2019;129:818-26. https://doi.org/10.1016/j.ijbiomac.2019.02.085
  29. Arazmjoo S, Es-haghi A, Mahmoodzadeh H. Evaluation of anti-cancer and antioxidant properties of nanoemulsions synthesized by Nigella Sativa L. tincture. Nanomedicine Journal. 2021;8(1).
  30. Khayatzadeh J, Es-haghi A, Shadan B. Anti-cancer effects of nanoemulsion prepared using Zingiber Officinale L. tincture against PC3 prostate cancer cells. Nanomedicine Journal. 2022;9(3).
  31. Seifi N, Mansoori R, Khoshbakht Marvi P, Niknam S, Zarrinnahad H, Amini N, et al. Anti-cancerous effect and biological evaluation of green synthesized Selenium nanoparticles on MCF-7 breast cancer and HUVEC cell lines. Nanomedicine Research Journal. 2023;8(4):373-82.
  32. Mousavi-Kouhi SM, Beyk-Khormizi A, Amiri MS, Mashreghi M, Yazdi MET. Silver-zinc oxide nanocomposite: From synthesis to antimicrobial and anticancer properties. Ceramics International. 2021;47(15):21490-7. https://doi.org/10.1016/j.ceramint.2021.04.160
  33. Seyedi Z, Amiri MS, Mohammadzadeh V, Hashemzadeh A, Haddad-Mashadrizeh A, Mashreghi M, et al. Icariin: A Promising Natural Product in Biomedicine and Tissue Engineering. Journal of Functional Biomaterials. 2023;14(1):44. https://doi.org/10.3390/jfb14010044
  34. Taghavizadeh Yazdi ME, Darroudi M, Amiri MS, Zarrinfar H, Hosseini HA, Mashreghi M, et al. Antimycobacterial, anticancer, antioxidant and photocatalytic activity of biosynthesized silver nanoparticles using Berberis Integerrima. Iranian Journal of Science and Technology, Transactions A: Science. 2022;46(1):1-11. https://doi.org/10.1007/s40995-021-01226-w
  35. Yazdi MET, Darroudi M, Amiri MS, Hosseini HA, Nourbakhsh F, Mashreghi M, et al. Anticancer, antimicrobial, and dye degradation activity of biosynthesised silver nanoparticle using Artemisia kopetdaghensis. Micro & Nano Letters. 2020;15(14):1046-50. https://doi.org/10.1049/mnl.2020.0387
  36. Ahmadi R, Es-haghi A, Zare-Zardini H, Taghavizadeh Yazdi ME. Nickel oxide nanoparticles synthesized by Rose hip extract exert cytotoxicity against the HT-29 colon cancer cell line through the caspase-3/caspase-9/Bax pathway. Emergent Materials. 2023:1-12. https://doi.org/10.1007/s42247-023-00572-2
  37. Velsankar K, Sudhahar S, Parvathy G, Kaliammal R. Effect of cytotoxicity and aAntibacterial activity of biosynthesis of ZnO hexagonal shaped nanoparticles by Echinochloa frumentacea grains extract as a reducing agent. Materials Chemistry and Physics. 2020;239:121976. https://doi.org/10.1016/j.matchemphys.2019.121976
  38. Shaheen TI, Fouda A, Salem SS. Integration of cotton fabrics with biosynthesized CuO nanoparticles for bactericidal activity in the terms of their cytotoxicity assessment. Industrial & Engineering Chemistry Research. 2021;60(4):1553-63. https://doi.org/10.1021/acs.iecr.0c04880
  39. Yazdi MET, Nourbakhsh F, Mashreghi M, Mousavi SH. Ultrasound-based synthesis of ZnO· Ag 2 O 3 nanocomposite: characterization and evaluation of its antimicrobial and anticancer properties. Research on Chemical Intermediates. 2021;47(3):1285-96. https://doi.org/10.1007/s11164-020-04355-w
  40. Khalil Abad MH, Nadaf M, Taghavizadeh Yazdi ME. Biosynthesis of ZnO. Ag2O3 using aqueous extract of Haplophyllum obtusifolium: Characterization and cell toxicity activity against liver carcinoma cells. Micro & Nano Letters. 2023;18(6):e12170. https://doi.org/10.1049/mna2.12170
  41. Es-haghi A, Javadi F, Yazdi MET, Amiri MS. The Expression of Antioxidant Genes and Cytotoxicity of Biosynthesized Cerium Oxide Nanoparticles Against Hepatic Carcinoma Cell Line. Avicenna Journal of Medical Biochemistry. 2019;7(1):16-20. https://doi.org/10.34172/ajmb.2019.04
  42. Modarres M, Taghavizadeh Yazdi ME. Elicitation improves phenolic acid content and antioxidant enzymes activity in salvia leriifolia cell cultures. Iranian Journal of Science and Technology, Transactions A: Science. 2021;45(3):849-55. https://doi.org/10.1007/s40995-021-01070-y
  43. Nadaf M, Amiri MS, Joharchi MR, Omidipour R, Moazezi M, Mohaddesi B, et al. Ethnobotanical Diversity of Trees and Shrubs of Iran: A Comprehensive Review. International Journal of Plant Biology. 2023;14(1):120-46. https://doi.org/10.3390/ijpb14010011
  44. Mousavi-Kouhi SM, Beyk-Khormizi A, Amiri MS, Mashreghi M, Hashemzadeh A, Mohammadzadeh V, et al. Plant Gel-Mediated Synthesis of Gold-Coated Nanoceria Using Ferula gummosa: Characterization and Estimation of Its Cellular Toxicity toward Breast Cancer Cell Lines. Journal of Functional Biomaterials. 2023;14(7):332. https://doi.org/10.3390/jfb14070332
  45. Soni V, Raizada P, Singh P, Cuong HN, Rangabhashiyam S, Saini A, et al. Sustainable and green trends in using plant extracts for the synthesis of biogenic metal nanoparticles toward environmental and pharmaceutical advances: A review. Environmental Research. 2021;202:111622. https://doi.org/10.1016/j.envres.2021.111622
  46. Yosri N, Khalifa SA, Guo Z, Xu B, Zou X, El-Seedi HR. Marine organisms: Pioneer natural sources of polysaccharides/proteins for green synthesis of nanoparticles and their potential applications. International Journal of Biological Macromolecules. 2021;193:1767-98. https://doi.org/10.1016/j.ijbiomac.2021.10.229
  47. Ishak NM, Kamarudin S, Timmiati S. Green synthesis of metal and metal oxide nanoparticles via plant extracts: an overview. Materials Research Express. 2019;6(11):112004. https://doi.org/10.1088/2053-1591/ab4458
  48. Taghavizadeh Yazdi ME, Qayoomian M, Beigoli S, Boskabady MH. Recent Advances in Nanoparticles Applications in Respiratory Disorders, a Review. Frontiers in Pharmacology. 2023;14:1059343. https://doi.org/10.3389/fphar.2023.1059343
  49. Bagherian MS, Zargham P, Zarharan H, Bakhtiari M, Mortezaee Ghariyeh Ali N, Yousefi E, et al. Antimicrobial and antibiofilm properties of selenium-chitosan-loaded salicylic acid nanoparticles for the removal of emerging contaminants from bacterial pathogens. World Journal of Microbiology and Biotechnology. 2024;40(3):86. https://doi.org/10.1007/s11274-024-03917-z
  50. Huang X, Chen X, Chen Q, Yu Q, Sun D, Liu J. Investigation of functional selenium nanoparticles as potent antimicrobial agents against superbugs. Acta biomaterialia. 2016;30:397-407. https://doi.org/10.1016/j.actbio.2015.10.041
  51. Filipović N, Ušjak D, Milenković MT, Zheng K, Liverani L, Boccaccini AR, et al. Comparative study of the antimicrobial activity of selenium nanoparticles with different surface chemistry and structure. Frontiers in bioengineering and biotechnology. 2021;8:624621. https://doi.org/10.3389/fbioe.2020.624621
  52. Ridha DM, Al-Awady MJ, Abd Al-Zwaid AJ, Balakit AA, Al-Dahmoshi HO, Alotaibi MH, et al. Antibacterial and antibiofilm activities of selenium nanoparticles-antibiotic conjugates against anti-multidrug-resistant bacteria. International Journal of Pharmaceutics. 2024;658:124214. https://doi.org/10.1016/j.ijpharm.2024.124214
  53. Alhawiti AS. Citric acid-mediated green synthesis of selenium nanoparticles: antioxidant, antimicrobial, and anticoagulant potential applications. Biomass Conversion and Biorefinery. 2024;14(5):6581-90. https://doi.org/10.1007/s13399-022-02798-2
  54. Mohammed EJ, Abdelaziz AE, Mekky AE, Mahmoud NN, Sharaf M, Al-Habibi MM, et al. Biomedical Promise of Aspergillus Flavus-Biosynthesized Selenium Nanoparticles: A Green Synthesis Approach to Antiviral, Anticancer, Anti-Biofilm, and Antibacterial Applications. Pharmaceuticals. 2024;17(7):915. https://doi.org/10.3390/ph17070915
  55. Vollmer W. Bacterial cell walls: peptidoglycan. Molecular Medical Microbiology: Elsevier; 2024. p. 45-67. https://doi.org/10.1016/B978-0-12-818619-0.00015-0
  56. Bu Q, Jiang D, Yu Y, Deng Y, Chen T, Xu L. Surface Chemistry Engineered Selenium Nanoparticles as Bactericidal and Immuno-modulating Dual-functional Agents for Combating Methicillin-resistant Staphylococcus aureus Infection. Drug Resistance Updates. 2024:101102. https://doi.org/10.1016/j.drup.2024.101102
  57. Nayak V, Singh KR, Singh AK, Singh RP. Potentialities of selenium nanoparticles in biomedical science. New Journal of Chemistry. 2021;45(6):2849-78. https://doi.org/10.1039/D0NJ05884J
  58. Mancuso G, Midiri A, Gerace E, Biondo C. Bacterial antibiotic resistance: the most critical pathogens. Pathogens. 2021;10(10):1310. https://doi.org/10.3390/pathogens10101310
Nanomedicine Research Journal
Volume 9, Issue 2
Spring 2024
Pages 195-205