Tehran University of Medical Sciences Nanomedicine Research Journal 2476-3489 11 1 2026 03 01 Prosthodontics in the Era of Nanomedicine: Advanced Nanotechnology Enhanced Implants and Periodontal Surgery for Functional Oral Reconstruction 27 40 737692 10.22034/nmrj.2026.01.004 EN Fatemeh Ataei Department of Prosthodontics, School of Dentistry, Dental Research Center, Hamadan University of Medical Sciences, Iran Seyed Mostafa Taghavi Department of Periodantics, School of Dentistry, Hamadan University of Medical Sciences, Hamadan, Iran Soheyl Khakbaz Department of Prosthodontics, School of Dentistry, Dental Research Center, Hamadan University of Medical Sciences, Iran Ahmad Mahmoudi Department of Prosthodontics, School of Dentistry, Dental Research Center, Hamadan University of Medical Sciences, Iran Ehsan Nasehi Nia Department of Prosthodontics, School of Dentistry, Dental Research Center, Hamadan University of Medical Sciences, Iran Shima Firouzi Department of Prosthodontics, School of Dentistry, Dental Research Center, Hamadan University of Medical Sciences, Iran Journal Article 2026 01 28 Nanotechnology is revolutionizing prosthodontics by enabling the manipulation of materials at the nanoscale, leading to significant enhancements in the properties of dental materials. This transformation is crucial for improving the performance of implants and periodontal surgeries, ultimately facilitating functional oral reconstruction. This review aims to explore the latest advancements in nanotechnology applications within prosthodontics, focusing on nanomaterials such as nanometals, nanoceramics, and nano resins. It seeks to provide a comprehensive overview of how these innovations can enhance the aesthetic, durability, and functionality of dental restorations. The integration of nanotechnology in prosthodontics not only improves material properties but also paves the way for future research and clinical applications, potentially leading to breakthroughs in oral health management and patient care.While the advancements in nanotechnology present numerous benefits, challenges such as regulatory hurdles and long-term biocompatibility remain critical considerations for its widespread adoption in clinical practice. https://www.nanomedicine-rj.com/article_737692_64fb3c4e0dda627924c6ed293df775c8.pdf