Nanomedicine Research Journal (Abbreviation: Nanomed Res J)

is an international, open access, peer-reviewed, electronic and print quarterly publication released by the Iranian Society of Nanomedicine (ISNM). Nanomedicine Research Journal publishes original research articles, review papers, mini review papers, case reports and short communications covering a wide range of field-specific and interdisciplinary theoretical and experimental results related to applications of nanoscience and nanotechnology in medicine including, but not limited to, diagnosis, treatment, monitoring, prediction and prevention of diseases, tissue engineering, nano bio-sensors, functionalized carriers and targeted drug delivery systems.

* Publication process of manuscripts submitted to Nanomed Res J is free of charge.

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About the publisher

Founded in 2011 by the leading of School of Advanced Technologies in medicine (SATiM), Tehran University of Medical Sciences (TUMS) and Iran Nanotechnology Initiative Council, the Iranian Society of Nanomedicine (ISNM) attempts to promote and develop medical nanotechnology in Iran. For more information about the publisher, please visit us at


Review Paper
Tungsten Disulfide Nanomaterials (WS2 NM) Application in Biosensors and Nanomedicine: A review

Sedigheh Niknam; Seyed Ahmad Dehdast; Omid Pourdakan; Mohammad Shabani; Mohammad Kazem Koohi

Volume 7, Issue 3 , July 2022, Pages 214-226

  Abstract:The development of nanotechnology has proposed new routes in the design of the novel device for medical and biological applications. Tungsten disulfide (WS2) is a transition metal dichalcogenides. Tungsten disulfide nanomaterial (WS2 NM) are new nanostructures that can be used as a new option ...  Read More

Original Research Article
Preparation of Fe3O4-Au @ Fe3O4-Ag Composite Nanoparticles and Cytotoxicity Study of kidney parameters in mice

Waleed K Abdulkadhim; Mahdi A. Mohammed

Volume 7, Issue 3 , July 2022, Pages 227-234

  Magnetic Fe3O4 nanoparticles covered with gold and silver particles were prepared by hydrothermal method, and for the successful coating of gold and silver particles on Fe3O4 surface, the nanoparticles showed good dispersion and solubility in the physiological phase. The obtained nanoparticles were characterized ...  Read More

Original Research Article
Sunlight-Assisted Fabrication of Silver Nanoparticles using Terminalia neotaliala Capuron Aqueous Bark Extract: Evaluation of In vitro Antioxidant and Anti-inflammatory Activities

Nirupa Shivanand Vernekar; Tarikere Chandrashekarappa Taranath

Volume 7, Issue 3 , July 2022, Pages 235-244

  Objective(s): Sunlight-assisted rapid fabrication of silver nanoparticles (AgNPs) using aqueous bark extract of Terminalia neotaliala Capuron (TnB-AgNPs) and evaluation of in vitro antioxidant and anti-inflammatory activities. Methods: Aqueous bark extract of T. neotaliala was used as a reducing ...  Read More

Original Research Article
Curcumin-loaded albumin nanoparticles synthesis, characterization and in-vitro evaluation of cytotoxic effects against U-87 MG cells

Masoumeh Keshavarz; Navid Ahmadi Nasab; Maryam Saeidifar; Sara Nikoofal; Omid Safa

Volume 7, Issue 3 , July 2022, Pages 245-253

  Objective(s): Curcumin (Cur) as a natural bioactive compound has shown potential capability to fight a variety of malignancies. In this study, bovine serum albumin nanoparticles (BSA NPs) were applied to improve bioavailability and increase the effectiveness of the hydrophobic curcumin against human ...  Read More

Original Research Article
Ag-ZnO nanoparticles: synthesis, characterization, antibacterial activity on S. mutans, along with cytotoxic effect on U87 cell line

Armita Forutan Mirhosseini; Hadi Jabbari; Alireza Nouralishahi; Zahra Bahman; Sana Yahyazadeh Jasour; Afsaneh Nekouei

Volume 7, Issue 3 , July 2022, Pages 254-263

  In here, we introduced a rapid and green synthesis route to prepare pure zinc oxide (ZnO) and silver-doped zinc oxide (Ag-dop-ZnO) nanoparticles (NP) using Prosopis farcta extract. The physic-chemical property of the synthesized NPs was identified using PXRD, FESEM, FT-IR, UV-Vis, and EDX devices. According ...  Read More

Original Research Article
Mesenchymal stem/stromal (MSCs)-derived exosome inhibits retinoblastoma Y-79 cell line proliferation and induces their apoptosis

Hadis Kheradjoo; Alireza Nouralishahi; Mohamad Saeid Hoseinzade Firozabdi; Saman Mohammadzadehsaliani

Volume 7, Issue 3 , July 2022, Pages 264-269

  Aims: Based on the literature, mesenchymal stem/stromal cell derived exosome has dual role in tumor therapy or progress. We evaluated the possible anti-tumor effect of the MSCs-exosome on retinoblastoma Y-79 cell cells in vitro.Methods: To verify the efficient isolation of exosome, the MSCs-exosome structure ...  Read More

Original Research Article
Design and Development of Chitosan Based Etravirine Nanosuspension

Sathesh Kumar Sukumaran; C. Venkatasubramaniyan

Volume 7, Issue 3 , July 2022, Pages 270-287

  Objective(s): The objective of this study was to design, develop, optimize, and evaluate Chitosan based Etravirine Nanosuspension to enhance their solubility and extent of release.Methods: The Chitosan based Etravirine Nanosuspension was formulated by the modified solvent evaporation combined ionic cross-linking ...  Read More

Original Research Article
Stem cell-derived nano-scale vesicles promotes the proliferation of retinal ganglion cells (RGCs) by activation PI3K/Akt and ERK pathway

Hamed Mahmoudi; Alireza Nouralishahi; Saman Mohammadzadehsaliani

Volume 7, Issue 3 , July 2022, Pages 288-293

  Objective(s): To evaluate the effects of the mesenchymal stem cell-derived exosome on the proliferation of retinal ganglion cells (RGCs)-5 cell line.Methods: Exosomes were isolated from the human bone marrow (BM)-derived MSCs. Exosomes characteristic were verified by western blotting and transmission ...  Read More

Original Research Article
Extracellular Vesicles isolated from mesenchymal stem cell (MSCs) negatively regulates human T cell survival by inducing caspase cascade and inhibiting anti-apoptotic proteins

Hamed Mahmoudi; Pooya Jafari Doudaran

Volume 7, Issue 3 , July 2022, Pages 294-300

  Objective(s): Extracellular Vesicles (EVs) transports active biomolecules between human many cells. As natural nanoparticles (NP), exosomes (Exo), plays important roles in the diagnosis and also treatment, of human disorders. Recently, it has been exhibited that mesenchymal stem cell (MSC)-derived Exo ...  Read More

Original Research Article
Impact of green-synthesized silver nanoparticles on cognitive function and fluorescence spectroscopy of redox status in the hippocampus

Sepideh Tarbali; Nasser Karimi; Mehran Alavi; Maryam Zahmatkesh

Volume 7, Issue 3 , July 2022, Pages 301-311

  Silver nanoparticles exposure is inevitable due to their use in medical products and the food industry. They cross the blood–brain barrier and accumulate in the cerebrum and little information is available regarding their neurotoxicity. We investigated the potential alterations in hippocampal cognitive ...  Read More

drug delivery
Cancer stem cells (CSCs): the blockage of metastatic and stemness properties by metal nanoparticles

Samin Shokravi; Farnoosh Ebrahimzadeh; Farnoosh Farahbod; Aref Nooraei

Volume 6, Issue 4 , November 2021, , Pages 304-326

  Cancer stem cells (CSCs) are comprised of hierarchically-organized subpopulations of cells with  distinguished phenotypes and tumorigenic capabilities that concrete to metastasis and cancer recurrence. According to related studies, their presence stands as the main reason of cancer associated fatalities. ...  Read More

Green Synthesis of Silver Nanoparticles using Catharanthus roseus: Its Antioxidant and Antibacterial Properties

Anand Kumar Keshari; Atul Srivastava; Sandip Chowdhury; Ragini Srivastava

Volume 6, Issue 1 , January 2021, , Pages 17-27

  AbstractObjectiveThe present work shows the green synthesis of silver nanoparticles using C. roseus extract and its antioxidant, free radicals scavenging and antibacterial activities. Methods The C. roseus extract synthesized silver nanoparticles (CrAgNPs) were characterized by X-ray diffractometry, ...  Read More

Green synthesis and characterization of zinc oxide nanoparticles using Berberis tinctoria Lesch. leaves and fruits extract of multi-biological applications.

Vignesh Arumugam; Selvakumar Subramaniam; Vasanth Krishnan

Volume 6, Issue 2 , April 2021, , Pages 128-147

  Abstract: The green synthesis of B. tinctoria zinc oxide nanoparticles (ZnO NPs) was rendered by using leaves and fruits extract. These extracts acted as a capping and reducing agent in stabilizing the formation of ZnO NPs. The obtained NPs were characterized by using absorption spectroscopy analysis ...  Read More

Development of biosensors for the detection of COVID-19

Hosna Zare; Ehsan Aryan; Zahra Meshkat; Fatemeh Gheybi; Alireza Neshani; Kiarash Ghazvini; Majid Rezayi

Volume 6, Issue 1 , January 2021, , Pages 11-16

  The world is currently challenging with the COVID-19 pandemic due to the SARS-CoV-2, a new member of coronaviruses which emerged in late December 2019. The rapid transmission of the disease made it a global concern that has attracted worldwide attention. As there have been no promising treatments or ...  Read More

Formulation, Characterization and Toxicity Assessment of Ginkgo Biloba Extract Solid Lipid Nanoparticle in female mice

Arezoo Jammanesh; Sepideh Arbabi Bidgoli; Solmaz Ghaffari; Mohammad Reza Avadi

Volume 6, Issue 1 , January 2021, , Pages 28-40

  Aims and Objectives: We aimed in present study to provide solid-lipid nanoparticle (SLN) of GBE and evaluate its oral safety in the light of recent discoveries on strong inhibitory effects of Ginkgo Biloba Leaf Extract (GBE) against Covid 19 and Influenza virus .Materials and Methods: Morphology and ...  Read More