Nanomedicine Research Journal (Abbreviation: Nanomed Res J)

is an international, open access, peer-reviewed, electronic and print quarterly publication released by the Iranian Society of Nanomedicine (ISNM). Nanomedicine Research Journal publishes original research articles, review papers, mini review papers, case reports and short communications covering a wide range of field-specific and interdisciplinary theoretical and experimental results related to applications of nanoscience and nanotechnology in medicine including, but not limited to, diagnosis, treatment, monitoring, prediction and prevention of diseases, tissue engineering, nano bio-sensors, functionalized carriers and targeted drug delivery systems.

* Publication process of manuscripts submitted to Nanomed Res J is free of charge.

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About the publisher

Founded in 2011 by the leading of School of Advanced Technologies in medicine (SATiM), Tehran University of Medical Sciences (TUMS) and Iran Nanotechnology Initiative Council, the Iranian Society of Nanomedicine (ISNM) attempts to promote and develop medical nanotechnology in Iran. For more information about the publisher, please visit us at


Review Paper
Au nanoparticles in the diagnosis and treatment of ovarian cancer: A new horizon in the personalized medicine

Firoozeh Abolhasani Zadeh; Elham Shahhosseini; Soheil Rasoolzadegan; Gülüzar Özbolat; Farnoosh Farahbod

Volume 7, Issue 1 , January 2022, Pages 1-18

  As the world's sixth prevalent malignancy among women, the increased rate of mortality in ovarian cancer (OC)  patients is due to late diagnosis that causes a high rate of proliferation within the abdominal cavity. The sensitivity of screening and detection methods for the diagnosis of ovarian cancer ...  Read More

Review Paper nanomedicine
Nanoparticles in the prevention, diagnosis, and treatment of the influenza virus

Mahboubeh Nazari; Farnoosh Ebrahimzadeh; Mojgan Falaki; Yasamin Hajimomeni; Rajender S. Varma; Nima Fallahnia

Volume 7, Issue 1 , January 2022, Pages 19-36

  Influenza virus have its place in the Orthomyxoviridae family, comprising four types of viruses namely influenza A, B, C, and D. Several methods are commonly used to diagnose influenza, including PCR, rapid test, viral culture, and immunofluorescence while antiviral drugs are available for the therapeutic ...  Read More

Original Research Article nanomedicine
Synergistic anticancer effect of silver nanoparticles and Measles virus vaccine strain against hormone-dependent and -independent breast cancer cells

Rajaa H Salih; Wajeeh Kachi Obead; Ahmed Majeed Al-Shammari

Volume 7, Issue 1 , January 2022, Pages 37-48

  Objective(s): This study aimed to prepare a stable colloidal silver nanoparticles (AgNPs) and assess its novelty combination therapy, which comprises AgNPs and lives attenuated Measles virus (MV) vaccine, to target breast cancer cells. The safety of the proposed therapy in normal breast epithelial cell ...  Read More

Original Research Article nanomedicine
Immune Response of Infected Lung Cells to Nanofluid Containing Carbon Nanotubes and Antibiotic

Maryam Mehdizadeh; Mojgan Sheikhpour; Iman Salahshourifar; Seyed Davar Siadat; Parvaneh Saffarian

Volume 7, Issue 1 , January 2022, Pages 49-55

  Background: Klebsiella pneumoniae (K.p) is one of the pathogens causing hospital-acquired infections, which has been prioritized by the WHO due to its increased resistance to a variety of antibiotics. Cytokines are pro-inflammatory markers and their secretion in macrophages changes in pulmonary pneumoniae. ...  Read More

Original Research Article
Raman Spectroscopy and Histopathology of Rat Bladder Cancer treated by Doxorubicin and Cisplatin using reduced graphene oxide as carrier

Wagner. J. Fávaro; Renata A., Villela; Helder J. Ceragioli; Nelson Duran

Volume 7, Issue 1 , January 2022, Pages 56-65

  Raman spectroscopy is a promising diagnostic technique used to identify different cancer types; however, few reports have correlated this information to histopathological analyses conducted in vivo or ex-vivo. It is well-known that using a set of techniques is important and necessary to get reliable ...  Read More

Original Research Article nanomedicine
In-vitro investigation of curcumin coated gold nanoparticles effect on human colorectal adenocarcinoma cell line

Abolfazl Akbari; Zahra Shokati Eshkiki; Sara Mayahi; Seyed Mohammad Amini

Volume 7, Issue 1 , January 2022, Pages 66-72

  Curcumin is a herbal supplement that has been mentioned for many biomedical applications. Several pieces of research demonstrated that curcumin could improve cancer chemotherapy, lagging the metastasis progress, and prevent healthy cells from radiation therapy damage. Through a simple and green synthesis ...  Read More

Original Research Article
Preparation and characterization of bovine serum albumin nanocarrier conjugated to exosome to sustained release of 5-flurouracil: Release and antitumoral evaluation

Ghazaleh Rahimi; Maryam Saeidifar; Monireh Ganjali; Esmaeil Salahi

Volume 7, Issue 1 , January 2022, Pages 73-82

  One of the new strategies for improving of chemotherapy in cancer treatment is the use of nanocarriers for sustained release of anticancer drugs. The present study aims to investigate the bovine serum albumin nanoparticles (BSANP) with exosomes (Exo) for prolonged release of 5-Flurouracil (5FU) as an ...  Read More

Original Research Article nanomedicine
Silver nanoparticles: biosynthesis and cytotoxic performance against breast cancer MCF-7 and MDA-MB-231 cell lines

Soodabeh Darvish; Mohammad saeed Kahrizi; Gülüzar Özbolat; Fatemeh Khaleghi; Zohreh Mortezania; Delaram Sakhaei

Volume 7, Issue 1 , January 2022, Pages 83-92

  Objective(s): A study was performed on the possibility of synthesizing silver nanoparticles (Ag-NPs) from Ducrosia Anethifolia Aqueous Extract for treating breast cancer MCF-7 and MDA-MB-231 cell lines.Methods: The application of Ducrosia Anethifolia Aqueous Extract caused a reduction in silver ions ...  Read More

Original Research Article nanomedicine
In vitro acaricidal activity of nano-SiO2 against Hyalomma spp. ticks and its toxicity

Roghayeh Norouzi; Sakineh Irani; Farzad Katiraee; Marzie Hejazy

Volume 7, Issue 1 , January 2022, Pages 93-98

  Objective(s): The Hyalomma species of ticks is hematophagous ectoparasites and responsible for transmission of protozoan, bacterial, rickettsial and viral infection in vertebrate animals and humans. Recently, nanobiotechnology is considered as a novel approach for the control of ticks. The aim of this ...  Read More

Original Research Article nanomedicine
Cytotoxic activity and Magnetic Behavior of green synthesized iron oxide nanoparticles on brain glioblastoma cells

Majid Reza Akbarizadeh; Mahin Naderifar; Farideh Mousazadeh; Niloofar Zafarnia; Mina Sarani

Volume 7, Issue 1 , January 2022, Pages 99-106

  Iron oxide nanoparticles are one of the most applied metal nanoparticles with advantageous properties in biomedicine that can be cost-effectively and rapidly produced through green synthesizing methods. The purpose of this study was to study the toxicity of iron oxide nanoparticles (Fe2O3 NPs), which ...  Read More

drug delivery
Cancer stem cells (CSCs): the blockage of metastatic and stemness properties by metal nanoparticles

Samin Shokravi; Farnoosh Ebrahimzadeh; Farnoosh Farahbod; Aref Nooraei

Volume 6, Issue 4 , November 2021, , Pages 304-326

  Cancer stem cells (CSCs) are comprised of hierarchically-organized subpopulations of cells with  distinguished phenotypes and tumorigenic capabilities that concrete to metastasis and cancer recurrence. According to related studies, their presence stands as the main reason of cancer associated fatalities. ...  Read More

Green Synthesis of Silver Nanoparticles using Catharanthus roseus: Its Antioxidant and Antibacterial Properties

Anand Kumar Keshari; Atul Srivastava; Sandip Chowdhury; Ragini Srivastava

Volume 6, Issue 1 , January 2021, , Pages 17-27

  AbstractObjectiveThe present work shows the green synthesis of silver nanoparticles using C. roseus extract and its antioxidant, free radicals scavenging and antibacterial activities. Methods The C. roseus extract synthesized silver nanoparticles (CrAgNPs) were characterized by X-ray diffractometry, ...  Read More

Green synthesis and characterization of zinc oxide nanoparticles using Berberis tinctoria Lesch. leaves and fruits extract of multi-biological applications.

Vignesh Arumugam; Selvakumar Subramaniam; Vasanth Krishnan

Volume 6, Issue 2 , April 2021, , Pages 128-147

  Abstract: The green synthesis of B. tinctoria zinc oxide nanoparticles (ZnO NPs) was rendered by using leaves and fruits extract. These extracts acted as a capping and reducing agent in stabilizing the formation of ZnO NPs. The obtained NPs were characterized by using absorption spectroscopy analysis ...  Read More

Development of biosensors for the detection of COVID-19

Hosna Zare; Ehsan Aryan; Zahra Meshkat; Fatemeh Gheybi; Alireza Neshani; Kiarash Ghazvini; Majid Rezayi

Volume 6, Issue 1 , January 2021, , Pages 11-16

  The world is currently challenging with the COVID-19 pandemic due to the SARS-CoV-2, a new member of coronaviruses which emerged in late December 2019. The rapid transmission of the disease made it a global concern that has attracted worldwide attention. As there have been no promising treatments or ...  Read More

Formulation, Characterization and Toxicity Assessment of Ginkgo Biloba Extract Solid Lipid Nanoparticle in female mice

Arezoo Jammanesh; Sepideh Arbabi Bidgoli; Solmaz Ghaffari; Mohammad Reza Avadi

Volume 6, Issue 1 , January 2021, , Pages 28-40

  Aims and Objectives: We aimed in present study to provide solid-lipid nanoparticle (SLN) of GBE and evaluate its oral safety in the light of recent discoveries on strong inhibitory effects of Ginkgo Biloba Leaf Extract (GBE) against Covid 19 and Influenza virus .Materials and Methods: Morphology and ...  Read More