Cytotoxic effects investigation of nanomicelle and free curcuminoids against cancer and normal cells

Elham Zendedel; Fatemeh Gheybi; Jamshidkhan Chamani; Mahmoud Reza Jaafari

Volume 4, Issue 2 , April 2019, , Pages 63-68

https://doi.org/10.22034/nmrj.2019.02.002

Abstract
  Abstract Curcumin, which is derived from the turmeric rhizomes (curcuma longa) as a natural polyphenol, is a substantially lipophilic molecule. This commonly used substance is employed as a spice and coloring agent in food and contains potent antioxidant, as well as anti-inflammatory, and anti-proliferative ...  Read More

Chemotherapeutic activity of Silymarin combined with doxorubicin liposomes in 4T1 breast cancer cells

Fatemeh Gheybi; Seyedeh Hoda Alavizadeh; Seyed Mahdi Rezayat; Elham Zendedel; Mahmoud Jaafari

Volume 4, Issue 1 , February 2019, , Pages 29-34

https://doi.org/10.22034/nmrj.2019.01.005

Abstract
  Cancer is the second leading cause of death worldwide. Despite great efforts over many years, today cancer treatment is not very effective. The main reasons for cancer chemotherapy failure are high cytotoxicity, low response rates in solid tumors, and development of resistance. Different experimental ...  Read More