Review Paper
Nanoparticles to overcome bacterial resistance in orthopedic and dental implants

Amir Aminian; Amirhossein Fathi; Mohammad Hadi Gerami; Maryam Arsan; Armita Forutan Mirhosseini; Torabizadeh Seyed Mohammad

Volume 7, Issue 2 , April 2022, Pages 107-123

http://dx.doi.org/10.22034/nmrj.2022.02.001

Abstract
  An implant is a device for replacing a damaged or deformed joint, bone, or cartilage. Considering the aging population and developing culture of active lifestyles, orthopedic and dental implants have found their stance as a fundamental component of medical sector, which is envisioned to be continuous. ...  Read More

Review Paper
Oral cancer: Nanoparticles as a new horizon in the diagnosis and phototherapy-based therapies

Nima Fallahnia; Legha Ansari; Hossein Mohammadkhani; Farideh Mousazadeh; Meysam Mohammadi khah; Golsa Ketabchi

Volume 7, Issue 2 , April 2022, Pages 124-139

http://dx.doi.org/10.22034/nmrj.2022.02.002

Abstract
  Oral cancer has affected the health of people by causing an unacceptable high rate of mortality and has the sixth place among the most common types of malignant cancer. In addition, the /available clinical approaches for the diagnosis and treatment of this disease (e.g., magnetic resonance imaging, computed ...  Read More

Original Research Article
The Characterization and Antileishmanial Evaluation on Leishmania Major with Chitosan/Zno Bio-Nanocomposite as Drug Delivery Systems

Mohsen Mahmoudi; Mohammad Shabani; Seyed Ahmad Dehdast; Sedigheh Saberi; Taher Elmi; Ghazaleh Chiari Fard; Fatemeh Tabatabaie; Sakineh Akbari

Volume 7, Issue 2 , April 2022, Pages 140-149

http://dx.doi.org/10.22034/nmrj.2022.02.003

Abstract
  Background: Leishmaniasis is a global disease that poses a threat to human life and is associated with complications. Current medications have limitations due to serious side effects, costs and drug resistance. Nanotechnology has received increased attention in recent years, owing to its extensive range ...  Read More

Original Research Article
Chitosan/PVA nanofibers for implantable drug delivery systems

Fatemeh Madani; Basil Mujokoro; Shima Mohammadi; Masood Khosravani; Mahdi Adabi

Volume 7, Issue 2 , April 2022, Pages 150-155

http://dx.doi.org/10.22034/nmrj.2022.02.004

Abstract
  In this study, we prepared methotrexate (MTX) loaded chitosan/polyvinyl alcohol (PVA) nanofibers using electrospinning method. The prepared nanofiber mats were soaked into the glutaraldehyde solution for crosslinking. The ratio of chitosan/PVA was 1:9 and 1:7, and the crosslinking time was 24 hrs and ...  Read More

Original Research Article
Cytotoxicity evaluation of synthesized silver nanoparticles by a Green method against ovarian cancer cell lines

Shahla Abbasi; Ahmet İlhan; Hadi jabbari; Parisa Javidzade; Maede Safari; Firoozeh Abolhasani Zadeh

Volume 7, Issue 2 , April 2022, Pages 156-164

http://dx.doi.org/10.22034/nmrj.2022.02.005

Abstract
  Objective(s): In recent years, the attention of many was focused on the features of the Green Synthesis process, such as its simplicity, cost-effectiveness, and environmental friendliness. This study investigates the feasibility of manufacturing silver nanoparticles from Malva sylvestris L aqueous extract ...  Read More

Original Research Article
Evaluation and comparison of physic-chemical properties and cytotoxic -performance of cerium oxide and zinc-doped cerium oxide nanoparticles

Faezeh khoshi; Foad Tosan; Sepehr Sadeghpour Tabaei; Negin Rahnama; Hesamoddin Arabnozari

Volume 7, Issue 2 , April 2022, Pages 165-172

http://dx.doi.org/10.22034/nmrj.2022.02.006

Abstract
  This paper presented the green synthesis of pure and 5% zinc doped cerium oxide nanoparticles (Zn-CeO2 NPs) by using the root extract of Prosopis farcta. Green synthesis is a method of synthesizing nanoparticles without the use of chemical solvents and is environmentally friendly and safe.The physic-chemical ...  Read More

Original Research Article
Zinc TetraPhenylPorphyrin / Dextran-Graft-PolyAcrylAmide / Gold Nanoparticles Hybrid Nanosystem for Photodynamic Therapy: Plasmonic Enhancement Effect

Oleg Yeshchenko; Nataliya Kutsevol; Anastasiya Tomchuk; Pavlo Khort; Pavlo A Virych; Vasyl A Chumachenko; Yulia I. Kuziv; Antonina P Naumenko; Andrey I Marinin

Volume 7, Issue 2 , April 2022, Pages 173-188

http://dx.doi.org/10.22034/nmrj.2022.02.007

Abstract
  Objective(s): In recent years, great attention towards alternative antitumor and antibacterial therapies such as antibacterial photodynamic therapy (PDT) has been raised. The development of nanotechnology has opened wide opportunities for the creation of new multifunctional hybrid multicomponent nanosystems ...  Read More

Original Research Article
Mesenchymal stem/stroma cell (MSC)-derived nanoscale exosomes inhibit T cell proliferation by negative regulation of PI3K/Akt and MAPK/ERK pathway

Mohammad Saeed Kahrizi; Sairan Maghsoodi; Faraz Ghayoumi; Hasti Etemadi; Soheila Aminzadeh; Kimia Safa; Samira Alesaeidi; Omar Saad Ahmed

Volume 7, Issue 2 , April 2022, Pages 189-194

http://dx.doi.org/10.22034/nmrj.2022.02.008

Abstract
  Objective(s): Exosomes, as membrane-enclosed nanovesicles (30–150 nm), transports active biomolecules between various cells. As natural nanoparticles (NP), they serve a key role in the diagnosis, treatment, as well as prevention of diseases. Recently it has been verified that MSC-derived exosomes ...  Read More

Original Research Article
Silver Nanoparticle-Induced Lymphocyte Activation in Zebrafish

Tarek Mahjoub; Saoussene Chernine; Rym Lahmar; Victor Gourain; Mohamed-Sofiane Mahjoub; Ahmed Rejeb; Mohamed-Néjib Romdane; Samir Ben Romdhane; Hafedh Abdelmelek

Volume 7, Issue 2 , April 2022, Pages 195-204

http://dx.doi.org/10.22034/nmrj.2022.02.009

Abstract
  Silver nanoparticles (Ag-NPs) are among the most widely used nanomaterials in the world. Nanotoxicological data on these additives remain unclear. The aim of this study is to evaluate the in vivo effects of Ag-NPs bioaccumulation on the hematological cells of adult zebrafish Danio rerio after three weeks ...  Read More

Original Research Article
Fabrication and characterization of chitosan/gelatin scaffold with bioactive glass reinforcement using PRP to regenerate bone tissue

Farhad Ghomi; Azadeh Asefnejad; Morteza Daliri; Vahabeddin Godarzi; Mehran Hemati

Volume 7, Issue 2 , April 2022, Pages 205-213

http://dx.doi.org/10.22034/nmrj.2022.02.010

Abstract
  In this study, the purpose of this study was to fabricate a porous nanocomposite chitosan-gelatin along with different weight percentages of bioglass using the freeze-drying method. In this study, the Platelet-rich plasma (PRP) technique was used for the first time to strengthen bone grafting. Tensile ...  Read More