Nanomedicine Research Journal

Nanomedicine Research Journal

Investigating the synthesis of tellurium nanoparticles and investigating its physicochemical and toxicological properties on fibroblast cells

Document Type : Original Research Article

Authors
Seyed Mohammad Amini 1
Rezvan kakolvand 2
Shahram Taeb 3
Hamideh Valizadeh 4
1 Radiation Biology Research Center, Iran University of Medical Sciences, Tehran, Iran
2 Medical Nanotechnology Department, School of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran
3 Department of Radiology, School of Paramedical Sciences, Guilan University of Medical Sciences, Rasht, Iran
4 Cell therapy Department, School of Advanced Technologies in Medicine, Iran University of Medical Sciences, Tehran, Iran
10.22034/nmrj.2024.04.004
Abstract
In recent years, metal nanoparticles have become very important in biomedical research. Among them, tellurium nanoparticles have received less attention. However, these structures have many applications in the treatment of malignancies and infections. For this purpose, we investigated the important aspects of the synthesis of tellurium nanoparticles for biomedical knives. However, the hydrodynamic diameter of the particles was estimated to be 35 nm, while, the average size of tellurium nanoparticles was 18.3 ± 4.3 nm based on the evaluation of TEM micrographs. The synthesized nanoparticles have a quasi-crystalline structure and have a broad absorption peak in the region of 550 nm. Our investigation reveals that the suitable washing procedure for synthesized metalloid nanoparticles is crucial for their biomedical properties including antioxidant activity and cytotoxic effects on mouse fibroblast cells if the synthesis of nanoparticles in the environment contains different chemicals, such an assumption can be made for other synthesized nanoparticles as well.
Keywords
Synthesis
Metalloids nanoparticles
Tellurium nanoparticles
cytotoxicity
Antioxidant activity

Subjects

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Nanomedicine Research Journal
Volume 9, Issue 4
Autumn 2024
Pages 373-380